Results 61 to 70 of about 102,041 (202)

Lactoferrin and Necrotizing Enterocolitis [PDF]

Clinics in Perinatology, 2013
Lactoferrin (LF) is a multifunctional protein and a member of the transferrin family. LF and lysozyme in breast milk kill bacteria. In the stomach, pepsin digests and releases a potent peptide antibiotic called lactoferricin from native LF. The antimicrobial characteristics of LF may facilitate a healthy intestinal microbiome.
Michael P, Sherman, Mindy M, Miller, Jan, Sherman, Victoria, Niklas   +3 more
openaire   +4 more sources

Comparison of necrotizing enterocolitis (NEC)-related apoptosis factors between preterm and full-term rats

Scientific Reports
The aim of this study was to determine whether there is a difference in the degree of apoptosis and the pathways leading to necrotizing enterocolitis (NEC) between preterm and full-term rat pups.
Hye-rim Lee, Dayoung Ko, Kyeung Yeup Lee, So young Kim, Joong Kee Youn, Hee Beom Yang, Hyun-Young Kim   +6 more
doaj   +1 more source

The human milk oligosaccharides 2’-Fucosyllactose and 6’-Sialyllactose protect against the development of necrotizing enterocolitis by inhibiting Toll-Like Receptor 4 signaling.

Pediatric Research, 2020
Background Necrotizing enterocolitis (NEC) develops through exaggerated toll-like receptor 4 (TLR4) signaling in the intestinal epithelium. Breast milk is rich in non-digestible oligosaccharides and prevents NEC through unclear mechanisms.
C. Sodhi, P. Wipf, Yukihiro Yamaguchi, W. Fulton, M. Kovler, D. Niño, Qinjie Zhou, E. Banfield, A. Werts, Mitchell R. Ladd, R. Buck, Karen C. Goehring, T. Prindle, Sanxia Wang, H. Jia, Peng Lu, D. Hackam   +16 more
semanticscholar   +1 more source

Trisomy 18 and necrotizing enterocolitis

Journal of Pediatric Surgery Case Reports, 2022
Introduction: Both Trisomy 18 (T18) and Necrotizing enterocolitis totalis (NEC-T) are major causes of morbidity and mortality in neonates. However, to our knowledge there has never been a case of a full-term infant born with both T18 and NEC-T published ...
Alexandra Maidan, Marla A. Sacks, Steven L. Raymond, Georgi D. Mladenov, Faraz A. Khan, Andrei Radulescu   +5 more
doaj   +1 more source

Temporal profile of intestinal tissue expression of intestinal fatty acid-binding protein in a rat model of necrotizing enterocolitis

Clinics
OBJECTIVES: Necrotizing enterocolitis is a severe multifactorial intestinal disorder that primarily affects preterm newborns, causing 20-40% mortality and morbidity.
Ana Leda Bertoncini Simões, Rebeca Lopes Figueira, Frances Lilian Lanhellas Gonçalves, Luís Felipe Tsuyoshi Mitidiero, Orlando Castro e Silva, José Luis Peiró, Lourenço Sbragia   +6 more
doaj   +1 more source

CUMULATIVE FLUID BALANCE OF INFUSION THERAPY OF NEWBORNS WITH NECROTIZING ENTEROCOLITIS

Сибирский научный медицинский журнал, 2019
The aim of the research is to study the connection between the five-day cumulative fluid balance and the outcome of a critical condition in the surgical group of newborns. Material and methods.
I. A. Al’Yanov, K. V. Budarova, S. I. Sirota, A. N. Shmakov   +3 more
doaj   +1 more source

The Role of Human Milk Oligosaccharides and Probiotics on the Neonatal Microbiome and Risk of Necrotizing Enterocolitis: A Narrative Review

Nutrients, 2020
Preterm infants are a vulnerable population at risk of intestinal dysbiosis. The newborn microbiome is dominated by Bifidobacterium species, though abnormal microbial colonization can occur by exogenous factors such as mode of delivery, formula feeding ...
Lila S. Nolan, Jamie M. Rimer, M. Good
semanticscholar   +1 more source

Worms, flies and four-legged friends: the applicability of biological models to the understanding of intestinal inflammatory diseases

Disease Models & Mechanisms, 2011
Diseases of intestinal inflammation, including Crohn’s disease, ulcerative colitis and necrotizing enterocolitis, cause substantial acute and chronic disability in a large proportion of the population.
Joyce Lin, David J. Hackam
doaj   +1 more source

Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities

Nature Communications, 2020
Necrotizing enterocolitis (NEC) is a severe, currently untreatable intestinal disease that predominantly affects preterm infants and is driven by poorly characterized inflammatory pathways.
Steven X Cho, Steven X Cho, Steven X Cho, I. Rudloff, I. Rudloff, J. C. Lao, J. C. Lao, Merrin A. Pang, Merrin A. Pang, R. Goldberg, C. Bui, C. Bui, Catriona McLean, Catriona McLean, Magdalena Stock, T. Klassert, H. Slevogt, Niamh E. Mangan, Niamh E. Mangan, W. Cheng, D. Fischer, S. Gfroerer, Manjeet K. Sandhu, Manjeet K. Sandhu, Devi Ngo, Devi Ngo, A. Bujotzek, L. Larivière, Felix Schumacher, G. Tiefenthaler, Friederike Beker, Friederike Beker, C. Collins, C. O. F. Kamlin, C. O. F. Kamlin, K. König, Atul Malhotra, Atul Malhotra, Atul Malhotra, Kenneth Tan, Kenneth Tan, Kenneth Tan, C. Theda, C. Theda, A. Veldman, A. Ellisdon, J. Whisstock, J. Whisstock, P. J. Berger, P. J. Berger, C. Nold-Petry, C. Nold-Petry, M. Nold, M. Nold, M. Nold   +54 more
semanticscholar   +1 more source

Nutrition in Necrotizing Enterocolitis and Following Intestinal Resection

Nutrients, 2020
This review aims to discuss the role of nutrition and feeding practices in necrotizing enterocolitis (NEC), NEC prevention, and its complications, including surgical treatment.
J. Ou, Cathleen M. Courtney, A. Steinberger, Maria E. Tecos, B. Warner   +4 more
semanticscholar   +1 more source