Results 21 to 30 of about 43,020 (182)

Gut bacteria and necrotizing enterocolitis: cause or effect? [PDF]

, 2015
Development of necrotising enterocolitis (NEC) is considered to be dependent on the bacterial colonisation of the gut. With little concordance between published data and a recent study failing to detect a common strain in infants with NEC, more questions
Bloch, Sune, Friis, Morten, Friis-Hansen, Lennart Jan, Martin-Bertelsen, Tomas, Nielsen, Michelle C., Rye-Jørgensen, Niklas, Sørensen, Mads Sølvsten, Winther, Ole   +7 more
core   +1 more source

A review of the immunomodulating components of maternal breast milk and protection against necrotizing enterocolitis [PDF]

, 2019
Breast milk contains immunomodulating components that are beneficial to newborns during maturation of their immune system. Human breast milk composition is influenced by an infant\u27s gestational and chronological age, lactation stage, and the mother ...
Fiorentino, Jinquan, Lila S. Nolan, Misty Good, Moe-Byrne, Olivia B. Parks   +5 more
core   +2 more sources

Neonatal Necrotizing Enterocolitis [PDF]

The Scientific World JOURNAL, 2011
Necrotizing enterocolitis (NEC) is a gastrointestinal disease that mostly affects premature infants. It involves infection and inflammation that causes destruction of the bowel. Although it affects only 1 in 2,000 to 4,000 births, or between 1 and 5% of neonatal intensive care unit admissions, NEC is the most common and serious gastrointestinal ...
Saad Lahmiti, Abdelmounaim Aboussad
openaire   +3 more sources

Dichotomous development of the gut microbiome in preterm infants. [PDF]

, 2018
BackgroundPreterm infants are at risk of developing intestinal dysbiosis with an increased proportion of Gammaproteobacteria. In this study, we sought the clinical determinants of the relative abundance of feces-associated Gammaproteobacteria in very low
Gilbert, Jack A, Groer, Maureen W, Ho, Thao TB, Kane, Bradley, Maheshwari, Akhil, Torres, Benjamin A, Yee, Alyson L   +6 more
core   +1 more source

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

Advanced Science, EarlyView.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai, Yaqi Li, Shengnan Liu, Minjuan Wu, Zhixiao Liu, Junfeng Jiang, Jingjing Chen, Xiaoding Xu, Li Li, Chaoqun Li, Fang Zhao, Ye Liu, Haitao Ni, Tengfei Zhang, Mingjuan Xu, Chaofeng Han   +15 more
wiley   +1 more source

Association of intestinal alkaline phosphatase with necrotizing enterocolitis among premature infants [PDF]

, 2019
Importance: Necrotizing enterocolitis (NEC) in preterm infants is an often-fatal gastrointestinal tract emergency. A robust NEC biomarker that is not confounded by sepsis could improve bedside management, lead to lower morbidity and mortality, and permit
Barkemeyer, Brian, Buckley, Rebecca, Davis, Porcha, Fang, Zhide, Gerber, Zeromeh, Gong, Qingqing, Good, Misty, Heath, Maya, Kim, Sunyoung, Linneman, Laura, Penn, Duna   +10 more
core   +1 more source

Surgical necrotizing enterocolitis [PDF]

Seminars in Perinatology, 2017
Although currently available data are variable, it appears that the incidence of surgical necrotizing enterocolitis (NEC) has not decreased significantly over the past decade. Pneumoperitoneum and clinical deterioration despite maximal medical therapy remain the most common indications for operative treatment.
Jamie R, Robinson, Eric J, Rellinger, L Dupree, Hatch, Joern-Hendrik, Weitkamp, K Elizabeth, Speck, Melissa, Danko, Martin L, Blakely   +6 more
openaire   +2 more sources

Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul, H. Rob Taal, Jan Mazela, Ryszard Lauterbach, Irwin K. M. Reiss, Karel Allegaert, Robert B. Flint, Sinno H. P. Simons   +7 more
wiley   +1 more source

The Neonatal Microbiome and Necrotizing Enterocolitis. [PDF]

, 2010
Necrotizing enterocolitis (NEC) is a devastating disorder that affects approximately 10% of premature infants. Its mortality remains high (15-30%), and its cause remains unknown.
Aaron Hamvas, Barbara Warner, Barbara Warner, Erica Sodergren, George Weinstock, Phillip Tarr, Vincent Magrini, William Shannon   +7 more
core   +2 more sources

External validation of calculator for cesarean delivery during induction of labor

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To validate a published risk calculator to predict cesarean delivery (CD) among singletons undergoing induction of labor. Methods Our retrospective cohort study included singletons undergoing induction of labor. A predicted CD score was calculated for each individual based on a previously developed calculator.
Claudia J. Ibarra, Rachel L. Wiley, Han‐Yang Chen, Estefania Guthrie, Ipsita Ghose, Hector Mendez‐Figueroa, Suneet P. Chauhan   +6 more
wiley   +1 more source