Results 31 to 40 of about 45,124 (242)
The role of mucosal immunity in the pathogenesis of necrotizing enterocolitis [PDF]
, 2017 Necrotizing enterocolitis (NEC) is the most devastating gastrointestinal disease of prematurity. Although the precise cause is not well understood, the main risk factors thought to contribute to NEC include prematurity, formula feeding, and bacterial ...
Bolock, Alexa M +2 more
core +2 more sources
Combined analysis of microbial metagenomic and metatranscriptomic sequencing data to assess in situ physiological conditions in the premature infant gut. [PDF]
, 2020 Microbes alter their transcriptomic profiles in response to the environment. The physiological conditions experienced by a microbial community can thus be inferred using meta-transcriptomic sequencing by comparing transcription levels of specifically ...
Baker, Robyn +8 more
core +2 more sources
A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis [PDF]
, 2016 During late gestation, villi extend into the intestinal lumen to dramatically increase the surface area of the intestinal epithelium, preparing the gut for the neonatal diet.
Bonder, Edward M. +13 more
core +1 more source
Clinics in Perinatology, 2012 Necrotizing enterocolitis (NEC) is the most common acquired gastrointestinal disease of premature neonates and is a serious cause of morbidity and mortality. NEC is one of the leading causes of death in neonatal intensive care units. Surgical treatment is necessary in patients whose disease progresses despite medical therapy.
Kathleen M, Dominguez, R Lawrence, Moss
openaire +3 more sources
Born too early and too small: higher order cognitive function and brain at risk at ages 8–16 [PDF]
, 2019 Prematurity presents a risk for higher order cognitive functions. Some of these deficits manifest later in development, when these functions are expected to mature. However, the causes and consequences of prematurity are still unclear.
Clark, Chris A. +12 more
core +5 more sources
The Microbiota of the Extremely Preterm Infant. [PDF]
, 2017 Colonization of the extremely preterm infant's gastrointestinal tract and skin begins in utero and is influenced by a variety of factors, the most important including gestational age and environmental exposures. The composition of the intestinal and skin
Sohn, Kristin, Underwood, Mark A
core +1 more source
New Microbes and New Infections, 2019 Clostridia—especially Clostridium butyricum—are among the taxa most frequently identified from stool samples of preterm neonates with necrotizing enterocolitis (NEC). Recently, Clostridium neonatale has also been detected from epidemic cases, but using a
M. Hosny +3 more
doaj +1 more source
Journal of Pediatric Surgery Case Reports, 2021 Spastic paraplegia 61 is a rare, complicated form of hereditary spastic paraplegia characterized by diffuse sensory and motor polyneuropathy. Knowledge about the clinical manifestations of disease in patients with this genetic condition is limited.
E.K. Ninmer +3 more
doaj +1 more source
Pediatric Clinics of North America, 1996 Necrotizing enterocolitis (NEC) is the most common severe neonatal gastrointestinal emergency that predominantly affects premature infants. Its morbidity and mortality is similar to other severe childhood diseases such as meningitis and leukemia, and is becoming increasingly recognized as a major cause of neurodevelopmental delays.
openaire +3 more sources
PLoS ONE, 2019 AimThe aim of this study was to evaluate long-term behavioural and neurodevelopmental complications of neonatal necrotizing enterocolitis at school age.MethodThis was a historic cohort study comparing all surviving children born in Denmark between 1st of
Mathias Lühr Hansen +4 more
doaj +1 more source