Results 21 to 30 of about 88,868 (230)

Association of intestinal alkaline phosphatase with necrotizing enterocolitis among premature infants [PDF]

, 2019
Importance: Necrotizing enterocolitis (NEC) in preterm infants is an often-fatal gastrointestinal tract emergency. A robust NEC biomarker that is not confounded by sepsis could improve bedside management, lead to lower morbidity and mortality, and permit
Barkemeyer, Brian, Buckley, Rebecca, Davis, Porcha, Fang, Zhide, Gerber, Zeromeh, Gong, Qingqing, Good, Misty, Heath, Maya, Kim, Sunyoung, Linneman, Laura, Penn, Duna   +10 more
core   +1 more source

Rules of Thumb for Estimating Drug Levels in Breast Milk: How Well Do They Work?

Clinical Pharmacology &Therapeutics, EarlyView.
The American Academy of Pediatrics and the World Health Organization recommend exclusive breastfeeding for the first 6 months of life due to extensive benefits for the maternal–infant dyad. While over 90% of mothers initiate breastfeeding, continuation drops to 35% by 6 months, often due to concerns about medication safety.
Juliya Gasparyan, Philip O. Anderson, Tamorah Lewis, Cindy H. T. Yeung   +3 more
wiley   +1 more source

The Neonatal Microbiome and Necrotizing Enterocolitis. [PDF]

, 2010
Necrotizing enterocolitis (NEC) is a devastating disorder that affects approximately 10% of premature infants. Its mortality remains high (15-30%), and its cause remains unknown.
Aaron Hamvas, Barbara Warner, Barbara Warner, Erica Sodergren, George Weinstock, Phillip Tarr, Vincent Magrini, William Shannon   +7 more
core   +2 more sources

Enfortumab vedotin plus pembrolizumab in treatment‐naïve metastatic urothelial carcinoma patients: An Austrian real‐world analysis

International Journal of Cancer, EarlyView.
What's New? New antibody‐drug conjugates (ADCs) and immunotherapies have helped expand treatment options for urothelial carcinoma (UC). Clinical trials suggest that the ADC enfortumab vedotin (EV) and the immunotherapeutic agent pembrolizumab, when used in combination, are especially effective against UC.
Dora Niedersuess‐Beke, Karl Mayrhofer, Johanna Krauter, Johannes Franke, Dominic Vais, Maximillian Pallauf, David Kiesl, Ferdinand Luger, Jacob Pfuner, Angelika Terbuch, Thomas Bauernhofer, Jasmin Spielgelberg, Andreas Banner, Stefan Aufderklamm, Clemens Wiesinger, Susanne Schnabel, Simon Peter Gampenrieder, Josef Mühlmann, Sonia Vallet, Sabine Weibrecht, Franz Stoiber, Haleh Andalibi, Harun Fajkovic, Hossein Taghizadeh, Jan Miechowiecki, Roman Taedcke, Daniel Heintel, Shahrokh F. Shariat, Martin Pichler, Wolfgang Hilbe, Renate Pichler   +30 more
wiley   +1 more source

Antenatal dexamethasone for late preterm delivery: Rate of complete course and neonatal outcomes

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This retrospective cohort study aimed to assess the rate of complete dexamethasone administration among late preterm deliveries and its impact on neonatal outcomes. Methods We reviewed medical records of 1500 late preterm deliveries (gestational age 34–36 + 6 weeks) between January 2018 and December 2020, analyzing baseline ...
Piyamon Srisakulpanich, Pattarawalai Talungchit, Tachjaree Panchalee, Chutima Yaiyiam   +3 more
wiley   +1 more source

Immunopathological properties of the Campylobacter jejuni flagellins and the adhesin CadF as assessed in a clinical murine infection model [PDF]

, 2019
Background: Campylobacter jejuni infections constitute serious threats to human health with increasing prevalences worldwide. Our knowledge regarding the molecular mechanisms underlying host-pathogen interactions is still limited.
Backert, Steffen, Bereswill, Stefan, Boehm, Manja, Escher, Ulrike, Heimesaat, Markus M., Mousavi, Soraya, Schmidt, Anna-Maria, Tegtmeyer, Nicole   +7 more
core   +4 more sources

Preterm meconium‐stained amniotic fluid: A red flag for infection and adverse perinatal outcomes

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Meconium‐stained amniotic fluid (MSAF) is uncommon in preterm deliveries and raises concerns about maternal and neonatal infectious risks. We aimed to evaluate maternal, perinatal, and microbiological outcomes in preterm deliveries complicated by MSAF compared to clear amniotic fluid (AF) and to assess outcomes in preterm versus term
Raneen Abu Shqara, Neta Hoffman, Lior Lowenstein, Maya Frank Wolf   +3 more
wiley   +1 more source

External validation of calculator for cesarean delivery during induction of labor

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To validate a published risk calculator to predict cesarean delivery (CD) among singletons undergoing induction of labor. Methods Our retrospective cohort study included singletons undergoing induction of labor. A predicted CD score was calculated for each individual based on a previously developed calculator.
Claudia J. Ibarra, Rachel L. Wiley, Han‐Yang Chen, Estefania Guthrie, Ipsita Ghose, Hector Mendez‐Figueroa, Suneet P. Chauhan   +6 more
wiley   +1 more source

Long‐term child outcomes after prenatal aspirin exposure: A 4‐year follow‐up of a randomized controlled trial (the APRIL study)

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To identify the long‐term child outcomes after prenatal aspirin exposure. Methods This study is a follow‐up of a randomized controlled trial (RCT) evaluating low‐dose aspirin in the prevention of recurrent spontaneous preterm labor (the APRIL study) comparing aspirin 80 mg daily (n = 194) to placebo (n = 193) in singletons.
Emilie V. J. van Limburg Stirum, Janneke van ’t Hooft, Anadeijda J. E. M. C. Landman, Martijn J. J. Finken, Anita C. J. Ravelli, Aleid G. Leemhuis, Eva Pajkrt, Martijn A. Oudijk, Marjon A. de Boer   +8 more
wiley   +1 more source

Candida auris, what do paediatricians need to know? [PDF]

, 2018
AW is supported by the Wellcome Trust Strategic Award (grant 097377) and the MRC Centre for Medical Mycology (grant MR/N006364/1) at the University of Aberdeen.Peer reviewedPublisher ...
Warris, Adilia
core   +1 more source