Necrotizing enterocolitis, gut microbes, and sepsis
Necrotizing enterocolitis (NEC) is a devastating disease in premature infants and the leading cause of death and disability from gastrointestinal disease in this vulnerable population.
David Hackam +2 more
exaly +2 more sources
Update on the Pathogenesis of the Hirschsprung-Associated Enterocolitis
Despite the significant progress that has been made in terms of understanding the pathophysiology and risk factors of Hirschsprung-associated enterocolitis (HAEC), the morbidity rate has remained unsatisfactorily stable, and clinical management of the ...
Shao-Tao Tang, Yichun Zhang, Kang Li
exaly +2 more sources
Necrotizing enterocolitis [PDF]
In necrotizing enterocolitis (NEC) the small (most often distal) and/or large bowel becomes injured, develops intramural air, and may progress to frank necrosis with perforation. Even with early, aggressive treatment, the progression of necrosis, which is highly characteristic of NEC, can lead to sepsis and death.
Pinchi S, Srinivasan +2 more
core +5 more sources
Global incidence of Necrotizing Enterocolitis: a systematic review and Meta-analysis [PDF]
Background Necrotizing Enterocolitis (NEC) is a major cause of morbidity and mortality in the Neonatal Intensive Care Unit (NICU), yet the global incidence of NEC has not been systematically evaluated.
A. Alsaied, N. Islam, L. Thalib
semanticscholar +2 more sources
Neutropenic enterocolitis [PDF]
We report a case of neutropenic enterocolitis diagnosed on computerized tomography abdomen in a 56-year-old man having high-grade non-Hodgkin's lymphoma. After appropriate management, the patient recovered completely.
Singhal, M. +3 more
openaire +3 more sources
Necrotizing enterocolitis: new insights into pathogenesis and mechanisms
Necrotizing enterocolitis (NEC) is the most frequent and lethal disease of the gastrointestinal tract of preterm infants. At present, NEC is thought to develop in the premature host in the setting of bacterial colonization, often after administration of ...
David Hackam, Diego F Nino
exaly +2 more sources
Incidence & Risk Factors for The Development of Transfusion-Associated Necrotizing Enterocolitis in Preterm Infants After Packed red Blood Cells Transfusion. A Prospective-Observational Study [PDF]
Background: Necrotizing enterocolitis (NEC) is a progressing inflammatory disease that is associated with high rates of morbidity and mortality in preterm babies. Transfusion-associated necrotizing enterocolitis (TANEC) is described as NEC where symptoms
Amira Sabry +3 more
doaj +1 more source
Identification and characterisation of mucin abnormalities in the ganglionic bowel in Hirschsprung's disease [PDF]
MDHirschsprung’s disease (HD) is a congenital abnormality of unknown origin, characterised by a lack of ganglion cells in the distal colon which results in functional colonic obstruction.
Speare, Ruth Marian
core +4 more sources
Clostridium difficile Induced Inflammasome Activation and Coagulation Derangements
C. difficile enterocolitis (CDAC) is the most common hospital infection, burdened by an increased incidence of coagulation-related complications such as deep vein thrombosis (DVT) and disseminated intravascular coagulation (DIC) as well as a significant ...
Marta Mattana +8 more
doaj +1 more source
Drug-induced enterocolitis syndrome: Similarities and differences compared with food protein-induced enterocolitis syndrome. [PDF]
In 2014, drug-induced enterocolitis syndrome (DIES) was described for the first time. It is still a poorly known disease with symptoms that typically resemble those of food protein-induced enterocolitis syndrome (FPIES).
Jean‐Christoph Caubet +16 more
core +1 more source

