Results 1 to 10 of about 5,824 (184)

Preoperative nutritional support in children with Hirschsprung disease: a prospective multicenter open-label randomized controlled trial [PDF]

Nature Communications
Preoperative undernutrition is prevalent among children with Hirschsprung disease (HSCR). To evaluate whether preoperative nutritional support reduces the incidence of postoperative HSCR-associated enterocolitis (HAEC), we conducted a prospective ...
Hong-yi Zhang, Ke Chen, Yanmin Zhang, Tingting Gao, Yuanyuan Huang, Liang Ge, Yuhang Yuan, Guofeng Zhang, Heying Yang, Hongxia Ren, Jianghua Zhan, Weijue Xu, Xiang Liu, Tianqi Zhu, Jiexiong Feng   +14 more
doaj   +2 more sources

Surgical management of short-segment Hirschsprung disease [PDF]

World Journal of Pediatric Surgery
Hirschsprung disease (HSCR) is the most common congenital motility disorder of the intestine, characterized by the absence of ganglion cells in the myenteric and submucosal plexuses, leading to functional bowel obstruction.
Haley Etskovitz, Rosa S Kim, Sarah Ziqi Wang, Prathima Nandivada   +3 more
doaj   +2 more sources

Identification and validation of the common pathogenesis and hub biomarkers in Hirschsprung disease complicated with Crohn’s disease

Frontiers in Immunology, 2022
BackgroundAlthough increasing evidence has supported that Hirschsprung disease (HSCR) is the risk factor for children developing Crohn’s disease (CD), the common mechanism of its co-occurrence remains unknown.
Jing Wang, Jing Wang, Zejian Li, Zejian Li, Jun Xiao, Jun Xiao, Luyao Wu, Luyao Wu, Ke Chen, Ke Chen, Tianqi Zhu, Tianqi Zhu, Chenzhao Feng, Didi Zhuansun, Didi Zhuansun, Xinyao Meng, Xinyao Meng, Jiexiong Feng, Jiexiong Feng   +18 more
doaj   +1 more source

Enterocolitis Is a Risk Factor for Bowel Perforation in Neonates With Hirschsprung's Disease: A Retrospective Multicenter Study

Frontiers in Pediatrics, 2022
Background and AimWe evaluated the clinical features of neonatal Hirschsprung's disease (HD)-associated bowel perforation (perforated HD) and investigated risk factors related to it.MethodsWe retrospectively collected clinical data of neonates (<1 ...
Tianqi Zhu, Tianqi Zhu, Guofeng Zhang, Xinyao Meng, Xinyao Meng, Jixin Yang, Jixin Yang, Yonghua Niu, Yonghua Niu, Ying He, Ying He, Heying Yang, Xiaofeng Xiong, Jiexiong Feng, Jiexiong Feng   +14 more
doaj   +1 more source

Investigation of The Histopathological and Histometric Changes in Rectum Tissue Biopsies of Hirschsprung and Non-Hirschsprung Disease in Neonate and Infant

Al-Mustansiriyah Journal of Science, 2023
Hirschsprung disease is one of the most common and problematic infancy and childhood maladies. The most reliable method for diagnosis is the histopathological analysis of colorectal biopsies and the typical finding of Hirschsprung disease is the absence
Rusul A. Abdul Hussein, Sahar A. H. AL-Sharqi, Ali E. Joda, Zaid Sharba   +3 more
doaj   +1 more source

Anorectal malformation and Hirschsprung disease in an otherwise healthy infant

Journal of Pediatric Surgery Case Reports, 2022
Background: Hirschsprung disease and anorectal malformations are two conditions that are rarely associated with one another. Current reports of anorectal malformations with concurrent Hirschsprung disease predominantly describe children with genetic ...
Audra Rougraff, Britney L. Grayson, Alan P. Ladd   +2 more
doaj   +1 more source

Hirschsprung's disease [PDF]

Seminars in Pediatric Surgery, 2010
Hirschsprung's disease (HSCR) is characterized by absence of the enteric nervous system in a variable portion of the distal gut. Affected infants usually present in the days after birth with bowel obstruction. Despite surgical advances, long-term outcomes remain variable.
GarciaBarcelo, M, Tam, PKH, Kenny, SE
openaire   +4 more sources

Application of toluidine blue stain and neuron specific enolase immunohistochemical stain in the diagnosis of hirschsprung disease

Bangabandhu Sheikh Mujib Medical University Journal, 2023
Hirschsprung disease is one of the most common and problematic infancy and childhood maladies. Early and accurate diagnosis is a fundamental step in proper management and prevention of complications.
Tasmia Islam, Sultana Gulshana Banu, Bishnu Pada Dey, Mohammad Mosiur Rahman, Papiya Rahman, Ummey Salma Shabnam, Syeeda Shiraj Um Mahmuda   +6 more
doaj   +1 more source

Colonic atresia and hirschsprung disease: a case report and review of the literature

Journal of Medical Case Reports, 2023
Background Colon atresia is one of the rarest congenital anomalies of the gastrointestinal tract, with an incident range of between 1 in 10,000 and 66,000 live births.
Amirhossein Ladan, Reza Mahdian Jouybari, Mahnaz Zareh Akbari, Pegah Moharrami Yeganeh   +3 more
doaj   +1 more source

New mutations associated with Hirschsprung disease

Anales de Pediatría (English Edition), 2020
Introduction: Hirschsprung Disease is caused by an impairment in cell migration from the neural crest to the gastrointestinal tract, resulting in an absence of neurons in the myenteric plexus.
Marta Lorente-Ros, Ane Miren Andrés, Alba Sánchez-Galán, Cinthia Amiñoso, Sixto García, Pablo Lapunzina, Jesús Solera-García   +6 more
doaj   +1 more source