Results 81 to 90 of about 11,603 (201)

PCR versus Hybridization for Detecting Virulence Genes of Enterohemorrhagic Escherichia coli

Emerging Infectious Diseases, 2007
We compared PCR amplification of 9 enterohemorrhagic Escherichia coli virulence factors among 40 isolates (21 O/H antigenicity classes) with DNA hybridization. Both methods showed 100% of the chromosomal and phage genes: eae, stx, and stx2.
Robert S. Gerrish, James E. Lee, June Reed, Joel Williams, Larry D. Farrell, Kathleen M. Spiegel, Peter P. Sheridan, Malcolm S. Shields   +7 more
doaj   +1 more source

Engineered Probiotics: The Next‐Generation Therapeutics to Combat Antibiotic‐Resistant Bacterial Infections

Food Frontiers, Volume 7, Issue 2, March 2026.
Engineered probiotics secretes fusion proteins which potentially neutralized the toxins secreted by other microbial communities. ABSTRACT On a global scale, the escalating burden of infectious diseases, predominantly attributed to bacterial pathogens, especially drug‐resistant strains, has progressed into a critical concern for clinical management and ...
Indu Singh, Raz Abdulqadir, Indira Kumari Verma, Yashika Awasthi, Arun Ratn, Juhi Sharma, Manmeet Rawat, Megh Singh Dhakad, Jasbir Dalal, Yash Gupta, Bhisham Narayan Singh, Divakar Sharma   +11 more
wiley   +1 more source

Survey on O157:H7 enterohemorrhagic Escherichia coli (EHEC) in cattle in Golestan province, Iran

Iranian Journal of Microbiology, 2014
Background and Objectives: A diverse group of Escherichia coli are known as enterohemorrhagic Escherichia coli (EHEC) including O157:H7 and non-O157 EHEC. Enterohemorrhagic strains are related to severe clinical conditions in humans including hemorrhagic
Alireza Koochakzadeh, Mahdi Askari-Badouei, Emad Mazandarani, Omid Madadgar   +3 more
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Interkingdom Interactions in the Gut: Ecological Mechanisms, Homeostasis, and Therapeutic Modulation

Gut Medicine, Volume 2, Issue 1, Page 23-39, March 2026.
ABSTRACT The gut microbiota constitutes a highly complex and dynamic ecosystem that profoundly influences host physiology, metabolism, and immunity. This review provides an integrative overview of the mechanisms through which gut microorganisms—particularly bacteria and fungi—interact with host cells and with each other to maintain intestinal ...
Rui‐Qi Wei, Xin‐Wei Sun, Hao‐Jie Huang, Yu‐Zhi Zhao, Shuang‐Jiang Liu, Chang Liu   +5 more
wiley   +1 more source

Molecular basis of binding between the global post-transcriptional regulator CsrA and the T3SS chaperone CesT

Nature Communications, 2018
CesT is a type III secretion system chaperone that interacts with the post-transcriptional regulator CsrA, which is important for the modulation of post-attachment signaling in enteropathogenic and enterohemorrhagic Escherichia coli.
Fei Ye, Fanli Yang, Ruijie Yu, Xi Lin, Jianxun Qi, Zhujun Chen, Yu Cao, Yuquan Wei, George F. Gao, Guangwen Lu   +9 more
doaj   +1 more source

Intratumoral bacteria engineered for tumor therapy

Interdisciplinary Medicine, Volume 4, Issue 2, March 2026.
This article comprehensively reviews engineered intratumoral bacteria used in tumor therapy. The concept development, characteristics, and engineering methods of intratumoral bacteria are summarized. The mechanisms and the translational significance by which engineered intratumoral bacteria interfere with tumor progression are discussed and highlighted.
Huajie Zhang, Zelin Chen, Zeyu Yao, Sishi Luo, Cheng Luo, Rui Yang, Hao Fu, Songyin Huang   +7 more
wiley   +1 more source

Prevalence of Non-O157:H7 Shiga Toxin-Producing Escherichia coli in Diarrheal Stool Samples from Nebraska

Emerging Infectious Diseases, 2000
We determined the prevalence of Shiga-toxin producing Escherichia coli (STEC) in diarrheal stool samples from Nebraska by three methods: cefixime-tellurite sorbitol MacConkey (CT-SMAC) culture, enterohemorrhagic E.
Paul D. Fey, R.S. Wickert, M.E. Rupp, T.J. Safranek, S.H. Hinrichs   +4 more
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E. coli and gut health—For the loser now will be later to win

The FEBS Journal, Volume 293, Issue 6, Page 1621-1623, March 2026.
In humans, commensal gut bacteria participate in a miniature nitrogen cycle, metabolizing dietary nitrate and nitrite. While these processes can generate harmful N‐nitrosamines, they may also produce beneficial nitric oxide (NO) or ammonium. Hager and colleagues demonstrate that E.
Jon O. Lundberg
wiley   +1 more source

Genomic Epidemiology and Machine Learning–Based Drug Discovery for Antimicrobial Resistant Diarrheagenic Escherichia coli

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
This study integrates genomic epidemiology and machine learning–based virtual screening to identify novel therapeutic candidates, Alatamide and Isosativan, with strong binding stability against multidrug‐resistant diarrheagenic Escherichia coli virulence targets, highlighting computational drug discovery as a promising strategy to combat antimicrobial ...
Ayesha Masood, Fatima Noor, Abdu Rehman, Mohsin Gulzar Barq, Shazia Iqbal, Muhammad Qasim Ali, Shahzad Ahmad, Syed Zeeshan Haider Naqvi   +7 more
wiley   +1 more source

Enteropathogenic bacteria associated with acute diarrheal disease in children

Acta Médica del Centro, 2017
Introduction: bacteria cause between 10% and 20% of infectious diarrheas, many do not self-limit and need specific surveillance and specific treatment against the possibility of a potentially epidemic or virulent agent to avoid dissemination and ...
Calixta Rosa Hernández del Sol, Gleiny Vázquez Hernández, Zendy Mesa Delgado, Rosa Isabel Bermúdez Alemán, Yenicet Sotolongo Rodríguez, Greisy Vázquez Hernández   +5 more
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