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The Effect of Mitomycin C on Induction of Shiga Toxin Production in Clinical STEC Isolates [PDF]
ToxinsEarly determination of the Shiga toxin type of Shiga toxin-producing Escherichia coli (STEC) is crucial for guiding STEC-infected patients for proper and timely treatment and patient care.
Surangi H. Thilakarathna +2 more
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Shiga Toxin: Expression, Distribution, and Its Role in the Environment
Toxins, 2011 In this review, we highlight recent work that has increased our understanding of the production and distribution of Shiga toxin in the environment. Specifically, we review studies that offer an expanded view of environmental reservoirs for Shiga toxin ...
Steven A. Mauro, Gerald B. Koudelka
exaly +3 more sources
PREPARATION AND PROPERTIES OF SHIGA TOXIN AND TOXOID [PDF]
Journal of Experimental Medicine, 1946 1. Shigella dysenteriae (Shiga) can, under the proper cultural conditions, produce a soluble toxin which is independent of the specific somatic polysaccharide antigen. A method is described for the rapid production of this toxin by an avirulent R variant of this organism. 2.
R J, DUBOS, J W, GEIGER
exaly +4 more sources
Hemolytic Uremic Syndrome Outbreak in Adults and Shiga Toxin–Producing Escherichia coli Negative for Locus of Enterocyte Effacement, France, 2025 [PDF]
Emerging Infectious DiseasesIn January 2025, the Escherichia coli National Reference Center of France detected an outbreak of hemolytic uremic syndrome (HUS) in adults, caused by Shiga toxin–producing E. coli negative for locus of enterocyte effacement (LEE). The outbreak included
Justine de Larminat +16 more
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Do the A Subunits Contribute to the Differences in the Toxicity of Shiga Toxin 1 and Shiga Toxin 2? [PDF]
Toxins, 2015 Shiga toxin producing Escherichia coli O157:H7 (STEC) is one of the leading causes of food-poisoning around the world. Some STEC strains produce Shiga toxin 1 (Stx1) and/or Shiga toxin 2 (Stx2) or variants of either toxin, which are critical for the ...
Debaleena Basu, Nilgun E. Tumer
doaj +3 more sources
Chemosensors, 2022 Foodborne bacteria have persisted as a significant threat to public health and to the food and agriculture industry. Due to the widespread impact of these pathogens, there has been a push for the development of strategies that can rapidly detect ...
Sabrina Petrucci +3 more
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Influence of temperature and pH on induction of Shiga toxin Stx1a in Escherichia coli
Frontiers in Microbiology, 2023 Shiga toxin-producing strains represent pathogenic group that is of concern in food production. The present study evaluated forty-eight E. coli isolates (11 with intact stx gene, while remaining isolates presented only stx-fragments) for Shiga toxin ...
Vinicius Silva Castro +2 more
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Shiga Toxins as Antitumor Tools [PDF]
Toxins, 2021 Shiga toxins (Stxs), also known as Shiga-like toxins (SLT) or verotoxins (VT), constitute a family of structurally and functionally related cytotoxic proteins produced by the enteric pathogens Shigella dysenteriae type 1 and Stx-producing Escherichia coli (STEC). Infection with these bacteria causes bloody diarrhea and other pathological manifestations
Robert, Aude, Wiels, Joëlle
openaire +3 more sources
Shiga and Shiga-like toxins [PDF]
Microbiological Reviews, 1987 Introduction . 206 Shiga Toxin in Shigella Spp. . 207 History . 207 Purification and Structure . 207 Mode of Action . 208 Receptor binding and internalization . 208 Inhibition of protein synthesis . 209 Immunology and Immunochemistry . 209 Genetics . 210 Role of Toxin in Disease . 210 Dysentery . 210 Diarrhea .210 HUS . 211 Shiga-like toxins in E. Coli
O'Brien, Alison D., Holmes, Randall K.
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The pathogenic mechanisms of Shiga toxin and the Shiga‐like toxins [PDF]
Molecular Microbiology, 1991 SummaryIt is now well documented that some enteric bacteria which cause diarrhoeal and/or dysenteric disease produce, at high levels, one or more of a family of protein toxins referred to as Shiga toxin and Shiga‐like toxins (SLTs; alternatively called verocytotoxins or VTs).
V L, Tesh, A D, O'Brien
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