Results 21 to 30 of about 48,086 (234)

Mild Illness during Outbreak of Shiga Toxin−Producing Escherichia coli O157 Infections Associated with Agricultural Show, Australia

Emerging Infectious Diseases, 2017
During a large outbreak of Shiga toxin−producing Escherichia coli illness associated with an agricultural show in Australia, we used whole-genome sequencing to detect an IS1203v insertion in the Shiga toxin 2c subunit A gene of Shiga toxin−producing E ...
Bhakti R. Vasant, Russell J. Stafford, Amy V. Jennison, Sonya M. Bennett, Robert J. Bell, Christine J. Doyle, Jeannette R. Young, Susan A. Vlack, Paul Titmus, Debra El Saadi, Kari A.J. Jarvinen, Patricia Coward, Janine Barrett, Megan Staples, Rikki M.A. Graham, Helen V. Smith, Stephen B. Lambert   +16 more
doaj   +1 more source

Laboratory Practices and Incidence of Non-O157 Shiga Toxin–producing Escherichia coli Infections

Emerging Infectious Diseases, 2012
We surveyed laboratories in Washington State, USA, and found that increased use of Shiga toxin assays correlated with increased reported incidence of non-O157 Shiga toxin–producing Escherichia coli (STEC) infections during 2005–2010.
Kathleen A. Stigi, J. Kathryn MacDonald, Anthony A. Tellez-Marfin, Kathryn H. Lofy   +3 more
doaj   +1 more source

Protection against Shiga Toxins [PDF]

Toxins, 2017
Shiga toxins consist of an A-moiety and five B-moieties able to bind the neutral glycosphingolipid globotriaosylceramide (Gb3) on the cell surface. To intoxicate cells efficiently, the toxin A-moiety has to be cleaved by furin and transported retrogradely to the Golgi apparatus and to the endoplasmic reticulum.
Simona Kavaliauskiene, Anne Dyve Lingelem, Tore Skotland, Kirsten Sandvig   +3 more
openaire   +4 more sources

Shiga toxin 2 from enterohemorrhagic Escherichia coli induces reactive glial cells and neurovascular disarrangements including edema and lipid peroxidation in the murine brain hippocampus

Journal of Biomedical Science, 2019
Background Shiga toxin 2 from enterohemorrhagic Escherichia coli is the etiologic agent of bloody diarrhea, hemolytic uremic syndrome and derived encephalopathies that may result to death in patients.
Clara Berdasco, Alipio Pinto, Valeria Calabró, David Arenas, Adriana Cangelosi, Patricia Geoghegan, Pablo Evelson, Jorge Goldstein   +7 more
doaj   +1 more source

Microvesicle Involvement in Shiga Toxin-Associated Infection

Toxins, 2017
Shiga toxin is the main virulence factor of enterohemorrhagic Escherichia coli, a non-invasive pathogen that releases virulence factors in the intestine, causing hemorrhagic colitis and, in severe cases, hemolytic uremic syndrome (HUS).
Annie Villysson, Ashmita Tontanahal, Diana Karpman   +2 more
doaj   +1 more source

Global and regional source attribution of Shiga toxin-producing Escherichia coli infections using analysis of outbreak surveillance data [PDF]

, 2019
Shiga toxin-producing Escherichia coli (STEC) infections pose a substantial health and economic burden worldwide. To target interventions to prevent foodborne infections, it is important to determine the types of foods leading to illness.
Devleesschauwer, Brecht, Gill, Alexander, Majowicz, Shannon, Pires, Sara M   +3 more
core   +2 more sources

Mutational analysis of the Shiga toxin and Shiga-like toxin II enzymatic subunits [PDF]

Journal of Bacteriology, 1990
The A-subunit polypeptides of Shiga toxin, the Shiga-like toxins (SLTs), and the plant lectin ricin inactivate eucaryotic ribosomes by enzymatically depurinating 28S rRNA. Comparison of the amino acid sequences of the members of the Shiga toxin family and ricin revealed two regions of significant homology that lie within a proposed active-site cleft of
M P, Jackson, R L, Deresiewicz, S B, Calderwood   +2 more
openaire   +2 more sources

Fighting Fire with Fire: Phage Potential for the Treatment of E. coli O157 Infection

Antibiotics, 2018
Hemolytic⁻uremic syndrome is a life-threating disease most often associated with Shiga toxin-producing microorganisms like Escherichia coli (STEC), including E. coli O157:H7.
Cristina Howard-Varona, Dean R. Vik, Natalie E. Solonenko, Yueh-Fen Li, M. Consuelo Gazitua, Lauren Chittick, Jennifer K. Samiec, Aubrey E. Jensen, Paige Anderson, Adrian Howard-Varona, Anika A. Kinkhabwala, Stephen T. Abedon, Matthew B. Sullivan   +12 more
doaj   +1 more source

Genotypic Characterization of Non-O157 Shiga Toxin–Producing Escherichia coli in Beef Abattoirs of Argentina [PDF]

, 2011
The non-O157 Shiga toxin-producing Escherichia coli (STEC) contamination in carcasses and feces of 811 bovines in nine beef abattoirs from Argentina was analyzed during a period of 17 months.
Carbonari, Claudia Carolina, del Castillo, Lourdes Leonor, D´Astek, B. A., Galli, Lucía, Irino, K., Leotta, Gerardo Anibal, Masana, Marcelo, Palladino, Pablo Martín, Rivas, M., Vilacoba, Elisabet   +9 more
core   +2 more sources

Treatment Strategies for Infections With Shiga Toxin-Producing Escherichia coli

Frontiers in Cellular and Infection Microbiology, 2020
Infections with Shiga toxin-producing Escherichia coli (STEC) cause outbreaks of severe diarrheal disease in children and the elderly around the world. The severe complications associated with toxin production and release range from bloody diarrhea and ...
Sabrina Mühlen, Sabrina Mühlen, Petra Dersch, Petra Dersch   +3 more
doaj   +1 more source