Clostridium perfringens epsilon toxin induces blood brain barrier permeability via caveolae-dependent transcytosis and requires expression of MAL. [PDF]
PLoS Pathogens, 2019 Clostridium perfringens epsilon toxin (ETX) is responsible for causing the economically devastating disease, enterotoxaemia, in livestock. It is well accepted that ETX causes blood brain barrier (BBB) permeability, however the mechanisms involved in this
Jennifer R Linden +7 more
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The Molecular Architecture and Mode of Action of Clostridium perfringens ε-Toxin [PDF]
ToxinsClostridium perfringens ε-toxin has long been associated with a severe enterotoxaemia of livestock animals, and more recently, was proposed to play a role in the etiology of multiple sclerosis in humans.
Richard W. Titball
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Induction of antitoxic antibody and preventive effect against porcine edema disease by the pentameric Stx2eB subunit vaccine [PDF]
Veterinary Research, 2023 Porcine edema disease (ED) is an enterotoxaemia that frequently occurs in 4–12 week-old piglets and results in high mortality. ED is caused by Shiga toxin 2e (Stx2e), produced by host-adapted Shiga toxin-producing Escherichia coli (STEC) strains.
Masaya Yoshimura +5 more
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A role for the Clostridium perfringens β2 toxin in bovine enterotoxaemia?
Veterinary Microbiology, 2002 Non-enterotoxigenic type A Clostridium perfringens are associated with bovine enterotoxaemia, but the alpha toxin is not regarded as responsible for the production of typical lesions of necrotic and haemorrhagic enteritis. The purpose of this study was to investigate the putative role of the more recently described beta2 toxin.
Manteca, Christophe +9 more
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Use of serum total protein as a proxy for passive transfer status in lambs. [PDF]
Vet RecAbstract Background Serum total protein (TP) is commonly used to investigate failure of passive transfer of immunity (FPTI) in cattle. This short communication explores the use of serum TP as a proxy of passive transfer (PT) status in lambs. Methods Blood samples were obtained from 434 lambs within 8‒24 hours of birth to measure serum immunoglobulin G (
Kelly RF +12 more
europepmc +2 more sources
Preparation and evaluation of alum precipitate and oil adjuvant multivalent vaccines against clostridium perfringens [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2021 Enterotoxaemia is one of the hazardous diseases of the livestock. In Pakistan prophylaxis failure is due to the vaccination with type D monovalent vaccine.
Madeeha TARIQ +7 more
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Phenotypic detection and genotyping of Clostridium perfringens associated with enterotoxemia in sheep in the Qassim Region of Saudi Arabia [PDF]
Veterinary World, 2021 Background and Aim: Enterotoxemia caused by Clostridium perfringens toxinotypes is an often fatal disease of sheep of all ages, with a substantial economic loss to the sheep industry. This study was conducted to isolate C.
Fehaid Alsaab +2 more
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Zoonotic diseases appeared to be a major hurdle to successful deer farming in Bangladesh [PDF]
Veterinary World, 2021 Background and Aim: Due to the diversified lifestyle and fancy ecology associated with Chitra deer (Axis axis), deer farming has become popular in Bangladesh. Diseases may be the common constrain of successful deer farming. This study aims to investigate
Sajeda Sultana +5 more
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Diagnosis of Clostridium perfringens strains isolated from enterotoxemia cases in sheep using polymerase chain reaction (PCR) technique [PDF]
Iraqi Journal of Veterinary Sciences, 2009 This study included diagnosis and typing of 100 bacterial isolates of Clostridium perfringens that isolated from enterotoxaemia cases in sheep in Hama province by using Multiplex PCR.
M. A. Hamad, N. Habra, A. Kalb-Allouz
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Enterotoxaemia in chinchillas [PDF]
Laboratory Animals, 1975 Clostridium perfringens (type D) toxin was identified as the cause of sudden deaths in chinchillas. The highest incidence was at 2-4 months of age. Only a few were observed with clinical signs before death occurred. A vaccination program was highly effective.
R W, Moore, H H, Greenlee
openaire +2 more sources