Translational Approach to Induce and Evaluate Verocytotoxic E. coli O138 Based Disease in Piglets
Pig livestock was influenced by several global concerns that imposed a re-thinking of the farming system, which included the reduction in chemical dependency and the development of antimicrobial alternatives.
Luciana Rossi +11 more
doaj +1 more source
Veal Calves Produce Less Antibodies against C. Perfringens Alpha Toxin Compared to Beef Calves
Enterotoxaemia is a disease with a high associated mortality rate, affecting beef and veal calves worldwide, caused by C. perfringens alpha toxin and perfringolysin.
Bonnie R. Valgaeren +13 more
doaj +1 more source
The experimental reproduction of enterotoxaemia in piglets [PDF]
1. Whole cultures ofClostridium welchii, Type C (organisms plus toxin), produced enterotoxaemia and death when fed to new-born piglets.2. The disease could rarely be produced by suspensions of washed organisms given in the same way but was readily initiated by feeding bacteria-free toxin from Type C cultures.3. Piglets dying from enterotoxaemia induced
H I, FIELD, R F, GOODWIN
openaire +2 more sources
The synergistic necrohemorrhagic action of Clostridium perfringens perfringolysin and alpha toxin in the bovine intestine and against bovine endothelial cells [PDF]
Bovine necrohemorrhagic enteritis is a major cause of mortality in veal calves. Clostridium perfringens is considered as the causative agent, but there has been controversy on the toxins responsible for the disease.
Deprez, Piet +10 more
core +2 more sources
The C-terminal domain of Clostridium perfringens alpha toxin as a vaccine candidate against bovine necrohemorrhagic enteritis [PDF]
Bovine necrohemorrhagic enteritis is caused by Clostridium perfringens and leads to sudden death. Alpha toxin, together with perfringolysin O, has been identified as the principal toxin involved in the pathogenesis.
Deprez, Piet +10 more
core +4 more sources
Rethinking our understanding of the pathogenesis of necrotic enteritis in chickens [PDF]
For decades, low doses of antibiotics have been used widely in animal production to promote growth. However, there is a trend to reduce this use of antibiotics in feedstuffs, and legislation is now in place in Europe to prohibit their use in this way. As
Van Immerseel, Filip +3 more
core +1 more source
Perfringolysin O: The Underrated Clostridium perfringens Toxin?
The anaerobic bacterium Clostridium perfringens expresses multiple toxins that promote disease development in both humans and animals. One such toxin is perfringolysin O (PFO, classically referred to as θ toxin), a pore-forming cholesterol-dependent ...
Stefanie Verherstraeten +10 more
doaj +1 more source
Clostridium perfringens epsilon toxin (Etx) is a pore forming toxin that causes enterotoxaemia in ruminants and may be a cause of multiple sclerosis in humans. To date, most in vitro studies of Etx have used the Madin-Darby canine kidney (MDCK) cell line.
Skye Marshall +6 more
doaj +1 more source
Pigs experimentally infected with Serpulina hyodysenteriae can be protected from developing swine dysentery by feeding them a highly digestible diet [PDF]
Weaner pigs (n = 72) were fed 1 of 4 diets. These were based on either cooked rice and animal protein, cooked rice and lupin, wheat and lupin, or wheat and animal protein. Twenty-six of the pigs were slaughtered after 1 month.
Siba, P.M., Pethick, D.W., Hampson, D.J.
core +2 more sources
Enterotoxaemia is one of the important pathologies caused by Clostridium perfringens, which produces intestinal and systemic disease in goats, sheep and other animals.
R. Pawaiya +5 more
semanticscholar +1 more source

