Modeling viral infectious diseases and development of antiviral therapies using human induced pluripotent stem cell-derived systems [PDF]
, 2015 The recent biotechnology breakthrough of cell reprogramming and generation of induced pluripotent stem cells (iPSCs), which has revolutionized the approaches to study the mechanisms of human diseases and to test new drugs, can be exploited to generate ...
Barzon, Luisa +6 more
core +2 more sources
Transplant Infectious Disease, EarlyView.ABSTRACT Background Respiratory viral infections (RVIs) can have distinct clinical presentations and outcomes in non‐lung solid organ transplant (SOT) recipients compared to non‐transplant and lung transplant patients. Understanding their impact is crucial for improving patient care and outcomes.
Manon L. M. Prins +11 more
wiley +1 more source
Human picornaviruses associated with neurological diseases and their neutralization by antibodies [PDF]
, 2017 Picornaviruses are the most commonly encountered infectious agents in mankind. They typically cause mild infections of the gastrointestinal or respiratory tract, but sometimes also invade the central nervous system.
Ang +22 more
core +1 more source
Stewardship of Molecular Diagnostics in Transplant Viral Infections
Transplant Infectious Disease, EarlyView.ABSTRACT The transplant environment requires special considerations when testing for viral infections as immunosuppression results in atypical infection profiles. Microbes otherwise considered commensals or causing mild disease can lead to severe infections in transplant environments. Therefore, guidelines tend to recommend broader microbial testing in
Scott Sugden +3 more
wiley +1 more source
Identification of Enterovirus C105 for the first time in New Zealand
Western Pacific Surveillance and Response, 2015 We report on the first identification of Enterovirus C105 (EV-C105) in New Zealand from a 52-year-old male hospitalized with mild respiratory tract symptoms.
Angela Todd, Susan Taylor, Q Sue Huang
doaj +1 more source
Entry by multiple picornaviruses is dependent on a pathway that includes TNK2, WASL, and NCK1 [PDF]
, 2019 Comprehensive knowledge of the host factors required for picornavirus infection would facilitate antiviral development.
Adamovich +60 more
core +2 more sources
Childhood acute leukemia and type 1 diabetes in children: A nationwide case–control study
International Journal of Cancer, Volume 158, Issue 4, Page 924-930, 15 February 2026.What's new? The etiology of childhood acute leukemia remains poorly understood. Accumulating evidence suggests a potential link between leukemia and autoimmune diseases. This nationwide, register‐based case–control study investigated the association between childhood acute leukemia and type 1 diabetes in Finland.
Julia Ventelä +4 more
wiley +1 more source
Construction Of Recombinant Bcg Expressing The Vp1 Antigen Of Enterovirus 71 For The Development Of A Candidate Vaccine [PDF]
, 2006 Enterovirus 71 (EV71), pencetus penyebab wabak penyakit tangan, kuku dan mulut (HMFD) di kalangan kanak-kanak telahpun dikenalpasti sebagai wabak yang diperlu dikawal segera Enterovirus 71 (EV71), the causativeing agent of outbreaks of hand, foot ...
Othman, Nurulhasanah
core +1 more source
Neurosyphilis presenting with papillitis [PDF]
, 2017 Syphilis is one of the oldest described infectious diseases in the world and is caused by the spirochete bacterium Treponema pallidum[1]. Although now a rare disease, incidence is increasing with the number of diagnoses of the disease rising in England ...
Cooper, Sarah +2 more
core +4 more sources
Rhinovirus Infects B and CD4 T Lymphocytes in Hypertrophic Tonsils in Children
Journal of Medical Virology, Volume 98, Issue 2, February 2026.ABSTRACT Prolonged detection of rhinovirus (RV) in secretions after a typical cold and asymptomatic shedding are frequently reported. Although RV has been detected in human hypertrophic tonsils, its replicative status and host cell range remain unclear.
Ronaldo Martins +14 more
wiley +1 more source