Results 71 to 80 of about 103,275 (259)

Mass‐Produced and High‐Performance Nanowell Biosensor Fabricated via Semiconductor Manufacturing for Rapid and Accurate COVID‐19 Diagnosis in the Clinical Field

open access: yesAdvanced Science, EarlyView.
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park   +11 more
wiley   +1 more source

CLINICAL-EPIDEMIOLOGICAL CHARACTERISTICS OF ENTEROVIRUS NONPOLIOMIELITIS INFECTIONS IN THE KRASNODAR TERRITORY

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2018
Aim. To characterize the epidemic situation and the clinical course of enterovirus (neolio) infections in the Krasnodar Territory. Materials and methods. Retrospective analysis of manifestations of the epidemic process and clinical characteristics of non-
L. I. Zhukova   +3 more
doaj   +1 more source

Molecular Characterization and Clinical Description of Non-Polio Enteroviruses Detected in Stool Samples from HIV-Positive and HIV-Negative Adults in Ghana

open access: yesViruses, 2020
In the post-polio eradication era, increasing attention is given to non-polio enteroviruses. Most of the data about enteroviruses in sub-Saharan Africa are related to acute flaccid paralysis surveillance and target the pediatric population.
Veronica Di Cristanziano   +13 more
doaj   +1 more source

Enterovirus 71: a whole virion inactivated enterovirus 71 vaccine

open access: yesExpert Review of Vaccines, 2016
Enterovirus A71 (EV71) is the predominant causative agent of hand, foot, and mouth disease (HFMD), which is often associated with severe cases and even deaths. EV71-associated epidemics have emerged as a serious threat to public health, particularly in the Asia-Pacific region.We searched PubMed using the terms 'enterovirus 71', 'hand, foot, and mouth ...
Yang, Zhou   +4 more
openaire   +2 more sources

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

open access: yesAdvanced Science, EarlyView.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang   +13 more
wiley   +1 more source

Enterovirus and enterovirus infections.

open access: yesAnnals of the Academy of Medicine, Singapore, 1988
An account of the nature of enterovirus and enterovirus infections with special reference to experiences encountered in Singapore is presented. The most common of enterovirus epidemic diseases since 1970 is Acute Haemorrhagic Conjunctivitis caused by Coxsackievirus A24 variant and Enterovirus type 70. Enterovirus of various serotypes were isolated from
M, Yin-Murphy, M C, Phoon, B, Ishak
openaire   +1 more source

Treatability of U.S. Environmental Protection Agency Contaminant Candidate List Viruses: Removal of Coxsackievirus and Echovirus using Enhanced Coagulation [PDF]

open access: yes, 2008
Enhanced coagulation was evaluated for removal efficacy of coxsackievirus and echovirus (Contaminant Candidate List [CCL] enteroviruses), poliovirus, four potential surrogate bacteriophages, and dissolved organic carbon (DOC).
Abbaszadegan, Morteza   +2 more
core   +1 more source

Atypical Clinical Course of Griscelli Syndrome Type 2 With Primarily Neurologic Presentation and Adult‐Onset in a 46‐Year‐Old Male

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Griscelli Syndrome Type 2 (GS2) is a rare autosomal recessive disorder caused by pathogenic mutations in the RAB27A gene. Typically, it is characterized by cutaneous hypopigmentation, immunodeficiency, with or without neurological abnormalities secondary to hemophagocytic lymphohistiocytosis (HLH). Without treatment, GS2 often results in fatal
Dzhoy Papingi   +6 more
wiley   +1 more source

Intraperitoneal infection of A/J and CD1 mice with coxsackievirus B2 and its mutants

open access: yesActa Virologica
Coxsackieviruses (CVs) belong to the genus Enterovirus and family Picornaviridae. Mutants can arise within the replication cycle of RNA viruses. The prototype CVB2 Ohio-1 (CVB2/O) strain adapted to rhabdomyosarcoma (RD) cells induced cytolytic infection ...
Maria Borsanyiova   +5 more
doaj   +1 more source

Targeted Anti‐IL‐1 Immunomodulatory Therapy in Pediatric Onset PPP1R13L‐Related Arrhythmogenic Cardiomyopathy

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive loss‐of‐function variants in PPP1R13L cause an ultra‐rare cardiocutaneous syndrome characterized by rapidly progressive arrhythmogenic cardiomyopathy (ACM). PPP1R13L encodes iASPP, which has two potentially overlapping mechanisms driving ACM as both a regulator of NFκB‐mediated inflammation and a binding partner within the ...
Aaron Renberg   +9 more
wiley   +1 more source

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