Rebound of Respiratory Virus Activity and Seasonality to Pre‐Pandemic Patterns
ABSTRACT The emergence of SARS‐CoV‐2 and the implementation of non‐pharmaceutical interventions (NPIs) profoundly disrupted the transmission dynamics of respiratory viruses, altering their epidemiology and seasonality. However, comprehensive long‐term data on these shifts and their post‐pandemic implications remain limited.
Rainer Gosert +18 more
wiley +1 more source
The Enterovirus 71 A-particle Forms a Gateway to Allow Genome Release: A CryoEM Study of Picornavirus Uncoating [PDF]
Since its discovery in 1969, enterovirus 71 (EV71) has emerged as a serious worldwide health threat. This human pathogen of the picornavirus family causes hand, foot, and mouth disease, and also has the capacity to invade the central nervous system to ...
AD Stuart +59 more
core +3 more sources
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro +5 more
wiley +1 more source
Sentinel Surveillance for Enterovirus 71, Taiwan, 1998
Outbreaks of enterovirus 71 have been reported around the world since 1969. The most recent outbreak occurred in Taiwan during April-July 1998. This hand, foot, and mouth disease epidemic was detected by a sentinel surveillance system in April at the ...
Trong-Neng Wu +7 more
doaj +1 more source
Should We Advance Our Understanding of Immunoglobulin E in Viral Immunity?
Immunoglobulin E has been extensively studied in allergies and parasitic diseases. Antigen‐specific IgE has been identified as part of the humoral response to viruses. This revision speculates on possible functionalities for IgE, such as neutralisation, cytotoxicity and immunopathology of viral diseases, and provide insights about gaps to fill in ...
Amanda Izeli Portilho +3 more
wiley +1 more source
First isolation of enterovirus 71 (EV-71) from Northern Brazil
Enterovirus 71 (EV-71) has been associated to cases of neurological disease in many countries including Brazil. This virus has now been reported from three of the five Brazilian regions.
Lamarão Leticia Martins +2 more
doaj
Timing of Endotracheal Intubation in Patients with Fulminant Enterovirus 71 Infection
Background and objective: Enterovirus 71 (EV 71) infections may result in the rapid progression of cardiopulmonary failure. Early endotracheal intubation is considered to be of primary importance.
Shen-Dar Chen +6 more
doaj +1 more source
Best practices to prevent transmission and control outbreaks of hand, foot, and mouth disease in childcare facilities: a systematic review. [PDF]
INTRODUCTION: Hand, foot, and mouth disease continues to cause seasonal epidemics in the Asia-Pacific Region. Since the current Enterovirus 71 vaccines do not provide cross-protection for all Enterovirus species that cause hand, foot, and mouth disease ...
CK Law +5 more
core +1 more source
Pantinin‐Derived Peptides against Veterinary Herpesviruses: Activity and Structural Characterization
Pantinin‐1 and pantinin‐2, scorpion venom–derived peptides, show potent antiviral activity against caprine and bovine herpesviruses. Acting via virucidal action and inhibition of viral entry/fusion, they adopt α‐helical structures in membrane‐mimetic environments. These structure–activity insights highlight their potential as therapeutic agents against
Rosa Giugliano +14 more
wiley +1 more source
Milrinone in Enterovirus 71 Brain Stem Encephalitis
Enterovirus 71 (EV71) was implicated in a widespread outbreak of hand-foot-and-mouth disease (HFMD) across the Asia Pacific area since 1997 and has also been reported sporadically in patients with brain stem encephalitis. Neurogenic shock with pulmonary
SHIH-MIN eWANG +2 more
doaj +1 more source

