Sophocarpine against enterovirus 71 in vitro
Sophocarpine (SCA) is a bioactive alkaloid present in Sophoraflavescens Ait. The present study demonstrated that SCA inhibited enterovirus 71 (EV71) infection in Vero cells. The results indicated that the 50% cytotoxicity concentration of SCA for Vero cells was 1,346 µg/ml, and the 50% inhibition concentration of SCA against EV71 was 350 µg/ml.
Zengjun, Jin +6 more
openaire +3 more sources
Sentinel surveillance for human enterovirus 71 in Sarawak, Malaysia: lessons from the first 7 years
Background A major outbreak of human enterovirus 71-associated hand, foot and mouth disease in Sarawak in 1997 marked the beginning of a series of outbreaks in the Asia Pacific region.
Yao Sik-King +13 more
doaj +1 more source
Tinnitus and Coxsackie B infections: A case series [PDF]
Tinnitus is a frequent and often debilitating condition. There is consensus in the scientific community that there exist various forms of tinnitus, which differ in their pathogenesis.
Coors, Hermann +6 more
core
First Report of a Fatal Case Associated with EV-D68 Infection in Hong Kong and Emergence of an Interclade Recombinant in China Revealed by Genome Analysis [PDF]
published_or_final_versio
Chan, JFW +10 more
core +1 more source
Genomic‐Based Epidemiological Analysis of the Post‐Pandemic Mycoplasma pneumoniae Resurgence
Phylogenetic analysis of a global collection of 562 M. pneumoniae genomes revealed six distinct lineages, including three newly emerged main Chinese clades (MCCs) that co‐circulated in various regions of China. The recent emergence of these distinct clades and their differing geographical distributions may suggest ongoing divergent evolution within the
Hongbo Liu +21 more
wiley +1 more source
Clinical and laboratory features of enteroviral meningitis course in adults and children
Objective – to determine the frequency of serous meningitis of enteroviral etiology and find out their clinical and laboratory features. Materials and Methods. The study included 51 patients with serous meningitis.
D. A. Zadiraka +3 more
doaj +1 more source
The influence of CpG and UpA dinucleotide frequencies on RNA virus replication and characterization of the innate cellular pathways underlying virus attenuation and enhanced replication [PDF]
Most RNA viruses infecting mammals and other vertebrates show profound suppression of CpG and UpA dinucleotide frequencies. To investigate this functionally, mutants of the picornavirus, echovirus 7 (E7), were constructed with altered CpG and UpA ...
Atkinson, Nicky J. +3 more
core +2 more sources
Bee products as alternatives in the treatment of viral infections
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba +3 more
wiley +1 more source
Anti-Enterovirus 71 Agents of Natural Products
This review, with 42 references, presents the fascinating area of anti-enterovirus 71 natural products over the last three decades for the first time. It covers literature published from 2005–2015 and refers to compounds isolated from biogenic sources ...
Liyan Wang +4 more
doaj +1 more source
Recent developments in antiviral agents against enterovirus 71 infection [PDF]
Enterovirus 71 (EV-71) is the main etiological agent of hand, foot and mouth disease (HFMD). Recent EV-71 outbreaks in Asia-Pacific were not limited to mild HFMD, but were associated with severe neurological complications such as aseptic meningitis and ...
Chee Tan +3 more
core +1 more source

