Results 81 to 90 of about 44,110 (248)

The State of Knowledge of the Primary and Secondary Metabolites of the Iris Genus

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
The genus Iris L. (Iridaceae) comprises over 320 species, primarily found in the northern hemisphere. Iris species are important in horticulture, folklore and medicine, and contain a variety of primary and secondary metabolites with significant biological activity.
Olha Mykhailenko   +3 more
wiley   +1 more source

Differential expression of miRNAs in enterovirus 71-infected cells [PDF]

open access: yes, 2015
BACKGROUND: Enterovirus 71 (EV71) is one of the major etiological pathogens of hand, foot and mouth disease (HFMD) and can cause severe cerebral and pulmonary complications and even fatality. MicroRNAs (miRNAs), a class of small non-coding RNA molecules,
Chao-Feng Ma   +4 more
core   +1 more source

Pyroptosis in Peripheral Neuropathy: From Molecular Mechanisms to Therapeutic Targeting

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Pyroptosis is a key inflammatory cell death pathway in peripheral neuropathy, with opposing roles: it perpetuates neuropathic pain but can be induced to kill neuroblastoma cells. This review consolidates mechanistic understanding and therapeutic strategies, arguing for a shift from disease‐centric to target‐centric treatment approaches to improve ...
Jinhuan Wei   +11 more
wiley   +1 more source

Sentinel Surveillance for Enterovirus 71, Taiwan, 1998

open access: yesEmerging Infectious Diseases, 1999
Outbreaks of enterovirus 71 have been reported around the world since 1969. The most recent outbreak occurred in Taiwan during April-July 1998. This hand, foot, and mouth disease epidemic was detected by a sentinel surveillance system in April at the ...
Trong-Neng Wu   +7 more
doaj   +1 more source

A novel mechanism underlying the innate immune response induction upon viral-dependent replication of host cell mRNA: A mistake of +sRNA viruses' replicases [PDF]

open access: yes, 2017
Viruses are lifeless particles designed for setting virus-host interactome assuring a new generation of virions for dissemination. This interactome generates a pressure on host organisms evolving mechanisms to neutralize viral infection, which places the
Colombo, Maria Isabel   +1 more
core   +2 more sources

Monkeypox Virus: Epidemiology, Virology, Diagnosis, Vaccine, and Therapeutics

open access: yesMedComm, Volume 7, Issue 1, January 2026.
This review provides a comprehensive overview of the latest research advances in MPXV, with a focused analysis across five core dimensions: epidemiology, virology, diagnosis, vaccine, and therapeutics. The primary objective of this review is to advance the understanding of MPXV and facilitate the development of more effective diagnostic methods ...
Yunzheng Yan   +14 more
wiley   +1 more source

Best practices to prevent transmission and control outbreaks of hand, foot, and mouth disease in childcare facilities: a systematic review. [PDF]

open access: yes, 2017
INTRODUCTION: Hand, foot, and mouth disease continues to cause seasonal epidemics in the Asia-Pacific Region. Since the current Enterovirus 71 vaccines do not provide cross-protection for all Enterovirus species that cause hand, foot, and mouth disease ...
CK Law   +5 more
core   +1 more source

The infection mechanism of enterovirus 71

open access: yesUirusu, 2012
Identification of a specific viral receptor is important for understanding the virus infection mechanism. I identified P-selectin glycoprotein ligand-1 (PSGL-1) as one of the functional receptors for enterovirus 71 (EV71), a pathogen that causes hand, foot, and mouth disease.
openaire   +3 more sources

Health Benefits and Therapeutic Potential of Quercetin

open access: yesJournal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Quercetin, a polyphenolic compound prevalent in many fruits, vegetables, and other dietary sources, has attracted considerable interest due to its extensive health benefits. This review examines its diverse biological properties, particularly its antioxidant and anti‐inflammatory effects. The study integrates recent scientific findings to elucidate the
Mahendra Aryal, Kim Wei Chan
wiley   +1 more source

Milrinone in Enterovirus 71 Brain Stem Encephalitis

open access: yesFrontiers in Pharmacology, 2016
Enterovirus 71 (EV71) was implicated in a widespread outbreak of hand-foot-and-mouth disease (HFMD) across the Asia Pacific area since 1997 and has also been reported sporadically in patients with brain stem encephalitis. Neurogenic shock with pulmonary
SHIH-MIN eWANG   +2 more
doaj   +1 more source

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