Results 71 to 80 of about 44,128 (189)

Full Genome Sequence of a Novel Human Enterovirus C (EV-C118) Isolated from Two Children with Acute Otitis Media and Community-Acquired Pneumonia in Israel

, 2013
The new enterovirus C strain EV-C118 belongs to the human enterovirus C species of the Picornaviridae family. We report the complete genome sequence of this strain, which was identified in respiratory specimens of two children hospitalized in Israel ...
D. Greenberg, C. Daleno, A. Scala, S. Esposito, N. Principi, A. Piralla, F. Baldanti   +6 more
core   +1 more source

Oncolytic Vaccinia Virus‐HSP70‐shRNA Amplifies Viral Replication, ROS/Autophagy, and Immunity to Fight Colorectal Cancer

Cancer Science, EarlyView.
OncoVV‑shHSP70, a vaccinia virus silencing HSP70, demonstrated potent antitumor efficacy in colorectal cancer cell lines, as well as in syngeneic, xenograft, and humanized mouse models. In cell lines, oncoVV‑shHSP70 promoted viral oncolysis and cytokine production through a self‑reinforcing cycle of ROS‑autophagy. In both CT26 and SW620‑humanized mouse
Rentao Yuan, Ruikang Liu, Fangying Shao, Zheqi Cai, Yingfei Fang, Kan Chen, Yanrong Zhou, Ting Ye, Gongchu Li   +8 more
wiley   +1 more source

The use of sialic acids as attachment factors is a common feature of Enterovirus-D species

Journal of Virology
Among the hundreds of enteroviruses (EVs) infecting humans, the members of the species EV-D (Enterovirus deconjuncti) display original traits. First, only five serotypes are known within this species, while other EV species have tens of serotypes each ...
Typhaine Filhol, Alice Mac Kain, Marie-Line Joffret, Nolwenn Jouvenet, Vincent Caval, Maël Bessaud   +5 more
doaj   +1 more source

Neurotropism In Vitro and Mouse Models of Severe and Mild Infection with Clinical Strains of Enterovirus 71

Viruses, 2017
Enterovirus 71 (EV71) is a common etiological agent of hand, foot, and mouth disease and fatal neurological diseases in children. The neuropathogenicity of severe EV71 infection has been documented, but studies comparing mouse models of severe and mild ...
Pin Yu, Linlin Bao, Lili Xu, Fengdi Li, Qi Lv, Wei Deng, Yanfeng Xu, Chuan Qin   +7 more
doaj   +1 more source

Experimental human rhinovirus and enterovirus interspecies recombination

, 2012
Human rhinoviruses (HRVs) and enteroviruses (HEVs), two important human pathogens, are non-enveloped, positive-sense RNA viruses of the genus Enterovirus within the family Picornaviridae.
Kaiser, Laurent, Manuel Schibler, Tapparel, Caroline, Caroline Tapparel, Schibler, Manuel, Laurent Kaiser, Daniel Gerlach, Gerlach, Daniel, Yannick Martinez, Lara Turin, Turin, Lara, Sandra Van Belle, Martinez, Yannick, Van Belle, Sandra   +13 more
core   +1 more source

Enterovirus D68 and other enterovirus serotypes identified in South African patients with severe acute respiratory illness, 2009–2011 [PDF]

, 2017
BACKGROUND : Human enteroviruses (EV) have been associated with severe acute respiratory illness (SARI) in South Africa. OBJECTIVES : We aimed to describe the molecular epidemiology of EV serotypes among patients hospitalized with SARI during 2009 ...
Kathleen Kahn, Marietjie Venter, Tempia, Stefano, Cohen, Adam L., Cheryl Cohen, Adam L. Cohen, Marthi Pretorius, Treurnicht, Florette K., Dawood, Halima, Florette K. Treurnicht, Cohen, Cheryl, Ebrahim Variava, Kahn, Kathleen, Stefano Tempia, Hellferscee, Orienka, Orienka Hellferscee, Venter, Marietjie, Halima Dawood, Variava, Ebrahim, Shabir A. Madhi, Pretorius, Marthi Andréa, Madhi, Shabir A.   +21 more
core   +1 more source

Genetic and phenotypic characterization of recently discovered enterovirus D type 111.

PLoS Neglected Tropical Diseases, 2019
Members of the species Enterovirus D (EV-D) remain poorly studied. The two first EV-D types (EV-D68 and EV-D70) have regularly caused outbreaks in humans since their discovery five decades ago but have been neglected until the recent occurrence of severe
Serge Alain Sadeuh-Mba, Marie-Line Joffret, Arthur Mazitchi, Marie-Claire Endegue-Zanga, Richard Njouom, Francis Delpeyroux, Ionela Gouandjika-Vasilache, Maël Bessaud   +7 more
doaj   +1 more source

Eccrine Squamous Syringometaplasia Mimicking Acute Cutaneous GVHD in a Pediatric HSCT Recipient: Case Report and Brief Review of the Indexed Literature

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Eccrine squamous syringometaplasia (ESS) is an uncommon reactive alteration of eccrine ducts, most often reported in oncologic and transplant settings, where it may clinically mimic acute cutaneous graft‐versus‐host disease (GVHD). We describe a 3‐year‐old boy with chronic granulomatous disease who developed a diffuse erythematous eruption 6 ...
Benedetta Galli, Cecilia Catapano, Iacopo Ghini, Mariateresa Rossi, Marina Venturini, Valeria Boccaletti   +5 more
wiley   +1 more source

Beyond the Kidney and Lung: Cutaneous and Mucosal Clues to Human Hantavirus Disease

International Journal of Dermatology, EarlyView.
Rodent exposure and aerosolized excreta can lead to hantavirus infection with systemic endothelial injury and capillary leak, resulting in thrombocytopenia and syndromes such as HPS/HCPS and HFRS/NE. Early dermatologic and mucosal findings, including flushing, conjunctival injection, petechiae/purpura, and mucosal bleeding, may provide important clues ...
Giuseppe Gallo, Pietro Quaglino, Simone Ribero   +2 more
wiley   +1 more source

The molecular basis of mouse adaptation by human enterovirus 71

, 2008
A mouse-adapted strain of human enterovirus 71 (HEV71) was selected by serial passage of a HEV71 clinical isolate (HEV71-26M) in Chinese hamster ovary (CHO) cells (CHO-26M) and in newborn BALB/c mice (MP-26M).
Chua, B.H., Nicholls, P.K., McMinn, P.C., Phuektes, P., Sanders, S.A.   +4 more
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