Detection and Characterization of Human Enteroviruses, Human Cosaviruses, and a New Human Parechovirus Type in Healthy Individuals in Osun State, Nigeria, 2016/2017 [PDF]
Viruses, 2019 Human enteroviruses and human parechoviruses are associated with a broad range of diseases and even severe and fatal conditions. For human cosaviruses, the etiological role is yet unknown. Little is known about the circulation of non-polio enteroviruses,
Folakemi Abiodun Osundare +7 more
doaj +4 more sources
Multiplexed High-Throughput Serological Assay for Human Enteroviruses [PDF]
Microorganisms, 2020 Immunological assays detecting antibodies against enteroviruses typically use a single enterovirus serotype as antigen. This limits the ability of such assays to detect antibodies against different enterovirus types and to detect possible type-specific ...
Niila V. V. Saarinen +7 more
doaj +9 more sources
A Novel Peptide from VP1 of EV-D68 Exhibits Broad-Spectrum Antiviral Activity Against Human Enteroviruses [PDF]
BiomoleculesEnteroviruses have been a historical concern since the identification of polioviruses in humans. Wild polioviruses have almost been eliminated, while multiple species of non-polio enteroviruses and their variants co-circulate annually.
Xiaojing Lin +9 more
doaj +4 more sources
ANTIVIRAL STRATEGIES FOR HUMAN ENTEROVIRUSES
International Journal of Infectious Diseases, 2023 Emerging and reemerging viral infections represent a major concern for human public health emergencies and there is an urgent need for the development of broad-spectrum antivirals and next generation vaccines.By using integrated system-wide approaches ...
Justin Chu
doaj +2 more sources
Frontiers in Microbiology, 2018 Human enteroviruses (EV) consist of more than 100 serotypes classified within four species for enteroviruses (EV-A to -D) and three species for rhinoviruses, which have been implicated in a variety of human illnesses. Being able to simultaneously amplify
Marie-Line Joffret +12 more
doaj +3 more sources
Genomic analysis of serologically untypable human enteroviruses in Taiwan. [PDF]
J Biomed Sci, 2019 Human enteroviruses contain over 100 serotypes. We have routinely conducted enterovirus surveillance in northern Taiwan; but about 10% of isolates could not be serotyped using traditional assays. Next-generation sequencing (NGS) is a powerful tool for genome sequencing.In this study, we established an NGS platform to conduct genome sequencing for the ...
Chien YS +8 more
europepmc +5 more sources
Identification and Phylogenetic Characterization of Human Enteroviruses Isolated from Cases of Aseptic Meningitis in Brazil, 2013–2017 [PDF]
Viruses, 2019 Aseptic meningitis is a common viral infection associated with human enteroviruses. The aim of the present study was to identify and characterize the enteroviruses associated with outbreaks and sporadic cases of aseptic meningitis that occurred in ...
Emanuelle Ramalho +13 more
doaj +2 more sources
African Non-Human Primates Host Diverse Enteroviruses. [PDF]
PLoS ONE, 2017 Enteroviruses (EVs) belong to the family Picornaviridae and are responsible for mild to severe diseases in mammals including humans and non-human primates (NHP).
Illich Manfred Mombo +18 more
doaj +6 more sources
Advances in Antiviral Drug Development Targeting Enteroviruses: From Viral Proteins to Host Factors [PDF]
VirusesEnteroviruses represent important human pathogens, posing a substantial disease burden, particularly in children under 5 years of age. Enteroviruses are the primary causative agents of hand-foot-and-mouth disease (HFMD) and are strongly associated with ...
Jiaying Lu +5 more
doaj +2 more sources
Progress in research on human enteroviruses
生物医学转化Since the identification of the poliovirus in 1908, over a hundred serotypes of enteroviruses have been discovered, capable of causing a range of diseases including hand, foot, and mouth disease, newborn sepsislike syndrome, aseptic meningitis, acute ...
Li Xiaohan +4 more
doaj +2 more sources