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Detection and Characterization of Human Enteroviruses, Human Cosaviruses, and a New Human Parechovirus Type in Healthy Individuals in Osun State, Nigeria, 2016/2017 [PDF]

open access: yesViruses, 2019
Human enteroviruses and human parechoviruses are associated with a broad range of diseases and even severe and fatal conditions. For human cosaviruses, the etiological role is yet unknown. Little is known about the circulation of non-polio enteroviruses,
Folakemi Abiodun Osundare   +7 more
doaj   +6 more sources

Multiplexed High-Throughput Serological Assay for Human Enteroviruses [PDF]

open access: yesMicroorganisms, 2020
Immunological assays detecting antibodies against enteroviruses typically use a single enterovirus serotype as antigen. This limits the ability of such assays to detect antibodies against different enterovirus types and to detect possible type-specific ...
Niila V. V. Saarinen   +7 more
doaj   +13 more sources

A Novel Peptide from VP1 of EV-D68 Exhibits Broad-Spectrum Antiviral Activity Against Human Enteroviruses [PDF]

open access: yesBiomolecules
Enteroviruses have been a historical concern since the identification of polioviruses in humans. Wild polioviruses have almost been eliminated, while multiple species of non-polio enteroviruses and their variants co-circulate annually.
Xiaojing Lin   +9 more
doaj   +4 more sources

ANTIVIRAL STRATEGIES FOR HUMAN ENTEROVIRUSES

open access: yesInternational Journal of Infectious Diseases, 2023
Emerging and reemerging viral infections represent a major concern for human public health emergencies and there is an urgent need for the development of broad-spectrum antivirals and next generation vaccines.By using integrated system-wide approaches ...
Justin Chu
doaj   +2 more sources

Efficacy of Inactivation of Human Enteroviruses by Dual-Wavelength Germicidal Ultraviolet (UV-C) Light Emitting Diodes (LEDs) [PDF]

open access: yesWater (Switzerland), 2019
The efficacy of germicidal ultraviolet (UV-C) light emitting diodes (LEDs) was evaluated for inactivating human enteroviruses included on the United States Environmental Protection Agency (EPA)’s Contaminant Candidate List (CCL). A UV-C LED device,
Hodon Ryu, Samuel L. Hayes, Sara E. Beck
exaly   +4 more sources

Identification and Phylogenetic Characterization of Human Enteroviruses Isolated from Cases of Aseptic Meningitis in Brazil, 2013–2017 [PDF]

open access: yesViruses, 2019
Aseptic meningitis is a common viral infection associated with human enteroviruses. The aim of the present study was to identify and characterize the enteroviruses associated with outbreaks and sporadic cases of aseptic meningitis that occurred in ...
Emanuelle Ramalho   +13 more
doaj   +2 more sources

Advances in Antiviral Drug Development Targeting Enteroviruses: From Viral Proteins to Host Factors [PDF]

open access: yesViruses
Enteroviruses represent important human pathogens, posing a substantial disease burden, particularly in children under 5 years of age. Enteroviruses are the primary causative agents of hand-foot-and-mouth disease (HFMD) and are strongly associated with ...
Jiaying Lu   +5 more
doaj   +2 more sources

Characterization of G-Quadruplexes in Enterovirus A71 Genome and Their Interaction with G-Quadruplex Ligands

open access: yesMicrobiology Spectrum, 2022
Human enteroviruses cause many diseases; however, there is no specific therapeutic drug. G-quadruplex is an atypical secondary structure formed in the guanine rich region of DNA or RNA, which can exist in the viral genome.
Lu Lv, Leiliang Zhang
doaj   +1 more source

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