SARS‐CoV‐2 nucleocapsid protein variants have differential RNA chaperone activity
The SARS‐CoV‐2 nucleocapsid (N) protein is not only the specific viral RNA packaging protein, but also acts as an RNA chaperone, facilitating RNA folding. We show that it facilitates RNA annealing through its RBD–IDR2–CTD region, identifying it as a functional RNA chaperone.
Sabrina Babl +11 more
wiley +1 more source
Abstract Background and objective The development of Type 1 diabetes (T1D) is shaped by genetic predisposition and epigenetic regulation. Human leukocyte antigen (HLA) risk alleles are major genetic determinants, but the epigenetic landscape in relation to disease onset remains unclear.
Shamila D. Alipoor +6 more
wiley +1 more source
Pathogenesis of enterovirus infection in central nervous system. [PDF]
Wang C, Li J, Liu Y, Sun Q, Liu Z.
europepmc +1 more source
Enterovirus infection and its relationship with neurodegenerative diseases. [PDF]
Sousa Junior IP, Vieira TCRG.
europepmc +1 more source
Severe neonatal enterovirus infection in twins with different outcomes: A case report. [PDF]
Storm KK +7 more
europepmc +1 more source
Pathogenic and Molecular Characteristics of Two Isolates of HEV-B Species [PDF]
Enteroviruses (EVs) are small non-enveloped RNA viruses forming a large group of different serotypes. EVs belong to the family Picornaviridae. The primary replication site of an enterovirus is typically the epithelium of the respiratory tract and the ...
Al-Hello, Haider
core
A Neonatal Murine Model for Caprine Enterovirus Infection and the Viral Tissue Tropism. [PDF]
Zhang Q +7 more
europepmc +1 more source
Mining the virome for insights into type 1 diabetes [PDF]
Park, Arnold, Zhao, Guoyan
core +2 more sources
Unveiling of the epidemiological patterns for caprine/ovine enterovirus infection in China. [PDF]
Hu J +8 more
europepmc +1 more source
Distinct transcriptomic profiles in children prior to the appearance of type 1 diabetes-linked islet autoantibodies and following enterovirus infection. [PDF]
Lin J +21 more
europepmc +1 more source

