Results 41 to 50 of about 61,811 (236)

Genetic characterization of human coxsackievirus A6 variants associated with atypical hand, foot and mouth disease: a potential role of recombination in emergence and pathogenicity [PDF]

, 2015
Human coxsackievirus A6 (CVA6) is an enterically transmitted enterovirus. Until recently, CVA6 infections were considered as being of minor clinical significance, and only rarely aetiologically linked with hand, foot and mouth disease (HFMD) associated ...
Gaunt, E, Harvala, H, Simmonds, P, Sreenu, VB, Thomson, E, Waris, M, Österback, R   +6 more
core   +1 more source

Enterovirus A71 Meningoencephalitis Outbreak, Rostov-on-Don, Russia, 2013

Emerging Infectious Diseases, 2015
Seventy-eight cases of enterovirus infection, including 25 neuroinfections, occurred in Rostov-on-Don, Russia, during May–June 2013. The outbreak was caused by an enterovirus A type 71 (EV-A71) subgenotype C4 lineage that spread to neighboring countries ...
Ludmila V. Akhmadishina, Marina V. Govorukhina, Evgeniy V. Kovalev, Svetlana A. Nenadskaya, Olga E. Ivanova, Alexander N. Lukashev   +5 more
doaj   +1 more source

Polymorphisms in the innate immune IFIH1 gene, frequency of enterovirus in monthly fecal samples during infancy, and islet autoimmunity. [PDF]

PLoS ONE, 2011
Interferon induced with helicase C domain 1 (IFIH1) senses and initiates antiviral activity against enteroviruses. Genetic variants of IFIH1, one common and four rare SNPs have been associated with lower risk for type 1 diabetes.
Elisabet Witsø, German Tapia, Ondrej Cinek, Flemming Michael Pociot, Lars C Stene, Kjersti S Rønningen   +5 more
doaj   +1 more source

Hospital discharges-based search of acute flaccid paralysis cases 2007-2016 in Italy and comparison with the National Surveillance System for monitoring the risk of polio reintroduction [PDF]

, 2019
Background: Acute flaccid paralysis (AFP) surveillance has been adopted globally as a key strategy for monitoring the progress of the polio eradication initiative.
Affanni P., Amato C., Ansaldi F., Arghittu A., Bellino S., Binda S., Bonaccorsi G., Brusaferro S., Buttinelli G., Camilloni B., Capannolo B., Carraro V., Castiglia P., D'errico M.M., De Grazia S., De Stefano C., Fiore S., Foca A., Fontana S., Germinario C., Giammanco G., Grasso G.M., Larocca A., Lombardi D., Lorini C., Mancini C., Napoletano G., Pellegrinelli L., Pennino F., Russo F., Spertini S., Stefanelli P., Triassi M., Vairo F., Veronesi L., Zanella F.   +35 more
core   +5 more sources

A novel mechanism underlying the innate immune response induction upon viral-dependent replication of host cell mRNA: A mistake of +sRNA viruses' replicases [PDF]

, 2017
Viruses are lifeless particles designed for setting virus-host interactome assuring a new generation of virions for dissemination. This interactome generates a pressure on host organisms evolving mechanisms to neutralize viral infection, which places the
Colombo, Maria Isabel, Delgui, Laura Ruth   +1 more
core   +2 more sources

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Acute flaccid paralysis with anterior myelitis - California, June 2012-June 2014. [PDF]

, 2014
In August 2012, the California Department of Public Health (CDPH) was contacted by a San Francisco Bay area clinician who requested poliovirus testing for an unvaccinated man aged 29 years with acute flaccid paralysis (AFP) associated with anterior ...
Ayscue, Patrick, Centers for Disease Control and Prevention (CDC), Clayton, Anna, Feikin, Daniel, Glaser, Carol, Harriman, Kathleen, Nix, William Allan, Padilla, Tasha, Pan, Chao, Reichel, John, Sejvar, James, Sheriff, Heather, Van Haren, Keith, Waldron, Paul, Watt, James, Waubant, Emmanuelle, Yagi, Shigeo, Yen, Cynthia   +17 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Pan-viral serology implicates enteroviruses in acute flaccid myelitis. [PDF]

, 2019
Since 2012, the United States of America has experienced a biennial spike in pediatric acute flaccid myelitis (AFM)1-6. Epidemiologic evidence suggests non-polio enteroviruses (EVs) are a potential etiology, yet EV RNA is rarely detected in cerebrospinal
Banerji, Debarko, Benson, Leslie, Bove, Riley, Briggs, Benjamin, Cheung, Carly K, Chitnis, Tanuja, Chiu, Charles Y, Chu, Victoria, Crawford, Emily D, DeRisi, Joseph L, Ding, Joy Z, Dominguez, Samuel R, Gelfand, Amy A, Glaser, Carol A, Gorman, Mark P, Hauser, Stephen L, Hawes, Isobel A, Johnson-Kerner, Bethany L, Khan, Lillian M, Konopka-Anstadt, Jennifer L, Krishnamoorthy, Kalpathy S, Lopez, Adriana S, Lyden, Amy, Marine, Rachel L, McMillan, Hugh J, Messacar, Kevin, Nash, Kendall, Ng, Terry Fei Fan, Nix, W Allan, O'Donovan, Brian D, Oberste, M Steven, Pak, John E, Ramachandran, Prashanth S, Ramesh, Akshaya, Sample, Hannah A, Schubert, Ryan D, Sit, Rene, Soldatos, Ariane, Sowa, Gavin M, Tan, Michelle, Tato, Cristina M, Wadford, Debra A, Wilson, Michael R, Wu, Wesley, Yen, Cynthia, Zorn, Kelsey C   +45 more
core  

A Role for the Intestinal Microbiota and Virome in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)? [PDF]

, 2016
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a heterogeneous disorder of significant societal impact that is proposed to involve both host and environmentally derived aetiologies that may be autoimmune in nature. Immune-related symptoms
Acheson, Bassi, Burbelo, Caligiuri, Carlo-Stella, Collins, Enbom, Fattah, Fremont, Gill, Jason, Klein, Klimas, Kumar, Lerner, Lerner, Maes, Meeus, Nishikai, Sharpe, Sheedy, Tannock, Vollmer-Conna   +22 more
core   +2 more sources