Enterovirus Infections Are Associated With the Development of Celiac Disease in a Birth Cohort Study [PDF]
Enterovirus and adenovirus infections have been linked to the development of celiac disease. We evaluated this association in children who developed biopsy-proven celiac disease (N = 41) during prospective observation starting from birth, and in control ...
Maarit Oikarinen+19 more
doaj +3 more sources
The TLR3/IRF1/Type III IFN Axis Facilitates Antiviral Responses against Enterovirus Infections in the Intestine [PDF]
Enteroviruses infect gastrointestinal epithelium cells, cause multiple human diseases, and present public health risks worldwide. However, the mechanisms underlying host immune responses in intestinal mucosa against the early enterovirus infections ...
Rui Su+11 more
doaj +3 more sources
Immunomodulatory Effects of Rhinovirus and Enterovirus Infections During the First Year of Life [PDF]
Early childhood infections have been implicated in the development of immune-mediated diseases, such as allergies, asthma, and type 1 diabetes. We set out to investigate the immunomodulatory effects of early viral infections experienced before the age of
Terhi Ruohtula+65 more
doaj +3 more sources
Retrospective Surveillance of Wastewater To Examine Seasonal Dynamics of Enterovirus Infections [PDF]
Enteroviruses are RNA viruses that are responsible for both mild gastroenteritis and mild respiratory illnesses as well as debilitating diseases such as meningitis and myocarditis.
Nichole E. Brinkman+2 more
doaj +3 more sources
Molnupiravir and Its Active Form, EIDD-1931, Show Potent Antiviral Activity against Enterovirus Infections In Vitro and In Vivo. [PDF]
Enterovirus infections can cause hand, foot, and mouth disease (HFDM), aseptic meningitis, encephalitis, myocarditis, and acute flaccid myelitis, leading to death of infants and young children.
Li Y+10 more
europepmc +2 more sources
Enterovirus Infections in Solid Organ Transplant Recipients: a Clinical Comparison from a Regional University Hospital in the Netherlands [PDF]
Enterovirus infections are known to cause a diverse range of illnesses, even in healthy individuals. However, information detailing enterovirus infections and their severity in immunocompromised patients, such as transplant recipients, is limited.
Hayley Cassidy+2 more
doaj +2 more sources
Enterovirus infections: Pivoting role of the adaptive immune response. [PDF]
Genus Enterovirus of the family Picornaviridae includes 12 species of which 7 species are human pathogens. Enteroviruses (EV) are transmitted via the fecal-oral route and respiratory transmission may also occur.
Bopegamage S.
europepmc +2 more sources
Treatment of Neonatal Enterovirus Infections. [PDF]
The human neonate is uniquely susceptible to serious, often fatal enterovirus infections in the first 2 weeks of life that are associated with acute maternal illness, premature delivery, male gender, and absence of maternal antibody against the infecting
J. Modlin
semanticscholar +4 more sources
Severe Enterovirus Infections in Hospitalized Children in the South of England: Clinical Phenotypes and Causative Genotypes. [PDF]
Background: Most enterovirus surveillance studies lack detailed clinical data, which limits their clinical usefulness. This study aimed to describe the clinical spectrum and outcome of severe enterovirus infections in children, and to determine whether ...
de Graaf H+10 more
europepmc +2 more sources
MicroRNA and Pathogenesis of Enterovirus Infection [PDF]
There are no currently available specific antiviral therapies for non-polio Enterovirus infections. Although several vaccines have entered clinical trials, the efficacy requires further evaluation, particularly for cross-strain protective activity ...
Bing-Ching Ho+2 more
doaj +3 more sources