Results 41 to 50 of about 42,771 (149)

Virtual Screening of Bacteriocins From Lactic Acid Bacteria Against Monkeypox DNA Polymerase: Sakacin P and Mundticin KS Emerge as Promising Candidates

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
This study employs an in silico virtual screening workflow to evaluate lactic acid bacteria (LAB)‐derived bacteriocins as potential inhibitors of the monkeypox virus DNA polymerase (MPDP). Protein‐peptide docking simulations using the HADDOCK platform revealed that Sakacin P and Mundticin KS possess the highest binding affinities for the MPDP target ...
Melisa Z. Karaman, Karan Goel, Fernando Berton Zanchi, Aykut Ozdarendeli, Somdutt Mujwar, Ahmet E. Yetiman, Ozkan Fidan   +6 more
wiley   +1 more source

Molnupiravir and Its Active Form, EIDD-1931, Show Potent Antiviral Activity against Enterovirus Infections In Vitro and In Vivo. [PDF]

Viruses, 2022
Li Y, Liu M, Yan Y, Wang Z, Dai Q, Yang X, Guo X, Li W, Chen X, Cao R, Zhong W.   +10 more
europepmc   +1 more source

Neonatal Bloodstream Infections: A Narrative Review on Diagnostic and Therapeutic Challenges and Prospects in Developing Countries

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Bloodstream infections (BSIs) pose a significant global health challenge, particularly in developing countries. Neonates are highly vulnerable due to underdeveloped immune systems and immature physical barriers, a risk amplified by poor hygiene and limited healthcare access in low‐ and middle‐income countries (LMICs), leading to an ...
Alex Odoom, Abdul‐Halim Osman, Onyansaniba K. Ntim, Fleischer C. N. Kotey, Eric S. Donkor   +4 more
wiley   +1 more source

The Burden of Viral Respiratory Infections in Immunosuppressed Inflammatory Bowel Disease Patients

JGH Open, Volume 10, Issue 8, August 2026.
ABSTRACT Background and Aim Due to the increasing immunosuppressant use in inflammatory bowel disease (IBD) and the risk of serious infections, this study investigates the prevalence and risk factors of respiratory pathogen detection in this population to improve patient care.
D. Huynh, E. Khoo, A. Shanmuga Anandan, J. Begun   +3 more
wiley   +1 more source

Human Metapneumovirus Versus Respiratory Syncytial Virus in the Pediatric Emergency Department: Inflammatory Indices, Cycle‐Threshold Profiles and Outcomes

Journal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT Inflammatory‐biomarker, cycle‐threshold (Ct) and co‐detection data on human metapneumovirus (hMPV) in the pediatric emergency department remain scarce. We retrospectively studied 203 children with multiplex RT‐PCR–confirmed respiratory virus positivity at a tertiary pediatric emergency department (January–May 2025).
Yılmaz Seçilmiş, Gülşah Kartal, Muhammet Sami Kayan, Mesut Kara, Ömür Mustafa Parkan, Selma Gökahmetoğlu   +5 more
wiley   +1 more source

Rhinovirus Species in Acute Respiratory Tract Infections and the Risk of Asthma in Children

Pediatric Pulmonology, Volume 61, Issue 8, August 2026.
ABSTRACT Background Rhinoviruses (RV) are the most common pathogens causing respiratory tract infections, and early childhood RV wheezing illnesses are a known risk factor for childhood asthma. The role of acute upper respiratory tract infections (URTI) caused by different RV species in asthma development is not well known.
Ville Forsström, Matti Waris, Ville Peltola, Laura Toivonen   +3 more
wiley   +1 more source

Efficient Assembly of Coxsackievirus A16 Virus‐Like Particles in Insect Cells via VP4‐Deficient P1 Expression

Entomological Research, Volume 56, Issue 8, August 2026.
ABSTRACT Coxsackievirus A16 (CVA16) is a major causative agent of hand, foot, and mouth disease (HFMD), yet efficient virus‐like particle (VLP)–based vaccine development remains challenging due to enteroviral structural complexity and the cytotoxicity of the 3CD protease required for polyprotein processing.
Hyun‐Soo Kim, Hyuk‐Jin Moon, Ra‐Mi Woo, Jae‐Bang Choi, Beom‐Ku Han, Soo Dong Woo   +5 more
wiley   +1 more source

Acute Myocarditis: From Pathophysiology to Risk‐Stratified Management—A Clinical Review

European Journal of Clinical Investigation, Volume 56, Issue 8, August 2026.
Stepwise approach to patients with suspected acute myocarditis, integrating the 2024 American College of Cardiology (ACC) four‐stage classification (Stages A–D) and the 2025 European Society of Cardiology (ESC) inflammatory myopericardial syndrome (IMPS) framework. Step 1 (Initial Assessment): clinical presentation, first‐line investigations (ECG, high‐
Michele Golino, Marco Giuseppe Del Buono, Michele Marchetta, Nicola Potere, Aldo Bonaventura, Alessandra Vecchiè, Danilo Malandrino, Giacomo Emmi, Jordana Kron, Antonio Abbate   +9 more
wiley   +1 more source

Eco‐Evolutionary Dynamics of Pathogen Epidemic Timing in a Seasonal Environment

Ecology Letters, Volume 29, Issue 8, August 2026.
How are seasonal patterns of pathogen epidemics shaped by evolution? Using numerical and analytical approaches, we investigate the evolution of pathogen seasonal preferences. Our analysis identifies two selective forces driving the diversification of pathogen seasonality: seasonal priority effect and stabilising selection.
Ryuichi Kumata, Akira Sasaki
wiley   +1 more source

Enterovirus D68 Detected in Hospitalized Children With Severe Acute Respiratory Infections in Zambia

Influenza and Other Respiratory Viruses, Volume 20, Issue 8, August 2026.
ABSTRACT Enterovirus D68 (EV‐D68) is a cause of severe acute respiratory infections (SARI) and is associated with acute flaccid paralysis. However, data on EV‐D68 in Africa, where SARI remains a leading cause of morbidity and mortality among children, remain limited.
Idah Mweene Ndumba, Michiko Okamoto, Paul Simusika, Takeaki Imamura, Mwaka Monze, Mayuko Saito, Hitoshi Oshitani   +6 more
wiley   +1 more source