Results 61 to 70 of about 45,941 (218)

Enterovirus A71 vaccine effectiveness in preventing enterovirus A71 infection among medically-attended hand, foot, and mouth disease cases, Beijing, China

Human Vaccines & Immunotherapeutics, 2019
Introduction: Enterovirus A71(EV-A71)-associated hand, foot, and mouth disease (HFMD) has been reported worldwide, and poses a particularly heavy burden on patients, families, and society in China. Three Chinese companies have licensed inactivated EV-A71
Xiaoli Wang, Zhijie An, Da Huo, Lei Jia, Jie Li, Yang Yang, Zhichao Liang, Quanyi Wang, Huaqing Wang   +8 more
doaj   +1 more source

An epidemiological surveillance of hand foot and mouth disease in paediatric patients and in community: A Singapore retrospective cohort study, 2013-2018.

PLoS Neglected Tropical Diseases, 2021
BackgroundWhile hand, foot and mouth disease (HFMD) is primarily self-resolving-soaring incidence rate of symptomatic HFMD effectuates economic burden in the Asia-Pacific region.
Nyo Min, Yasmin Hui Binn Ong, Alvin X Han, Si Xian Ho, Emmerie Wong Phaik Yen, Kenneth Hon Kim Ban, Sebastian Maurer-Stroh, Chia Yin Chong, Justin Jang Hann Chu   +8 more
doaj   +1 more source

The Autophagic Machinery in Enterovirus Infection [PDF]

Viruses, 2016
The Enterovirus genus of the Picornaviridae family comprises many important human pathogens, including polioviruses, rhinovirus, enterovirus A71, and enterovirus D68. They cause a wide variety of diseases, ranging from mild to severe life-threatening diseases.
Jeffrey Lai, I-Ching Sam, Yoke Chan
openaire   +3 more sources

Enterovirus immunity and maternal enterovirus infections - connection to type 1 diabetes [PDF]

, 2005
Tyypin 1 diabetes on insuliininpuutostauti, joka johtuu insuliinia tuottavien haiman beta-solujen tuhoutumisesta. Suomessa tyypin 1 diabeteksen ilmaantuvuus on korkein maailmassa.
Viskari, Hanna
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Neurodevelopmental Disorder with Dystonia and Chorea Linked to De Novo Variants in the Splicing Regulator SRRM4

Movement Disorders, EarlyView.
Abstract Background SRRM4 is an exclusively neural‐expressed splicing‐factor gene not yet associated with a monogenic condition. Objective We sought to delineate movement disorders caused by SRRM4 variants. De novo splice‐donor‐site variants at position +2 of intron 5 of SRRM4 (c.464+2T>C, c.464+2T>A) occurred in three unrelated patients with dystonia ...
Philip Harrer, Volker Kittke, Alice Saparov, Alexej Knaus, Shimriet Zeidler, Rachel Schot, Florian Kraft, Matthias Begemann, Suzanna Koudijs, Ugo Sorrentino, Chen Zhao, Ivana Dzinovic, Martin Pavlov, Elisabeth Graf, Antonia M. Stehr, Peter M. Krawitz, Christian Wilhelm, Saskia Biskup, Fahd Alsalloum, Steffen Berweck, Juliane Winkelmann, Konrad Oexle, Ingo Kurth, G. Christoph Korenke, Michael Zech   +24 more
wiley   +1 more source

In Vivo Persistence of Human Rhinoviruses in Immunosuppressed Patients.

PLoS ONE, 2017
Several species of the genus Enterovirus cause persistent infections in humans. Human rhinovirus (HRV) infections are generally self-limiting but occasionally persistent infections have been described.
Ilka Engelmann, Anny Dewilde, Mouna Lazrek, Mathilde Batteux, Aminati Hamissi, Ibrahim Yakoub-Agha, Didier Hober   +6 more
doaj   +1 more source

Association of Salivary Micro Ribonucleic Acid Levels With the Severity of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Children

Pediatric Discovery, EarlyView.
This cohort study of 395 children (mean age 7 years) with SARS‐CoV‐2 demonstrates that measuring levels of miR‐296‐5p in saliva at the time of initial clinical presentation may aid the prognosis of severe symptoms. ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) may impact immune‐related micro ribonucleic acids (miRNAs).
Steven D. Hicks, Dongxiao Zhu, Nirupama Kannikeswaran, Kathleen Meert, Wei Chen, Rhea Sullivan, Srinivasan Suresh, Usha Sethuraman   +7 more
wiley   +1 more source

Oncolytic Vaccinia Virus‐HSP70‐shRNA Amplifies Viral Replication, ROS/Autophagy, and Immunity to Fight Colorectal Cancer

Cancer Science, EarlyView.
OncoVV‑shHSP70, a vaccinia virus silencing HSP70, demonstrated potent antitumor efficacy in colorectal cancer cell lines, as well as in syngeneic, xenograft, and humanized mouse models. In cell lines, oncoVV‑shHSP70 promoted viral oncolysis and cytokine production through a self‑reinforcing cycle of ROS‑autophagy. In both CT26 and SW620‑humanized mouse
Rentao Yuan, Ruikang Liu, Fangying Shao, Zheqi Cai, Yingfei Fang, Kan Chen, Yanrong Zhou, Ting Ye, Gongchu Li   +8 more
wiley   +1 more source

Maternal and childhood enterovirus infections and the risk of beta-cell autoimmunity [PDF]

, 2005
Tyypin 1 diabetes on krooninen, elinikäinen sairaus, jota hoidetaan sairastumisesta lähtien päivittäin useilla insuliinipistoksilla. Sairaus johtuu haimassa sijaitsevien insuliinia tuottavien beetasolujen tuhoutumisesta.
Sadeharju, Karita
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Enterovirus Surveillance--United States, 1970-2005 [PDF]

"PROBLEM: Enteroviruses are common human viruses associated with various clinical syndromes, from minor febrile illness to severe, potentially fatal conditions (e.g., aseptic meningitis, paralysis, myocarditis, and neonatal enteroviral sepsis).

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