Results 1 to 10 of about 2,222 (126)

Epidemiological and Clinical Characteristics of the Enterovirus D68 Outbreak in Spain in 2024. [PDF]

J Med Virol
ABSTRACT Enterovirus D68 (EV‐D68) is a significant cause of respiratory and neurological disease worldwide. In 2024, Spain experienced its largest recorded EV‐D68 outbreak, accounting for 37.4% of all typed EV (294/892). This study describes the epidemiological, clinical, and phylogenetic features of EV‐D68 infections.
Camacho J, García-Ibáñez N, Fernández-García MD, Biya Y, Ruiz de Pedro E, Gutiérrez A, Nieto MC, Ruiz-García MM, Pastor-Fajardo MT, Lagarejos E, de Leonardo Simón C, Navascués A, Moreno-Docón A, Gozalo-Marguello M, Berengua C, Antequera P, Huéscar-Pascual MD, Calvo C, Cabrerizo M.   +18 more
europepmc   +2 more sources

Respiratory enterovirus D68: virology, clinical surveillance, host-pathogen interactions, and therapeutic prospects [PDF]

Frontiers in Cellular and Infection Microbiology
Enterovirus D68 (EV-D68), a unique enterovirus resembling human rhinoviruses, was long considered to cause only sporadic outbreaks of mild, self-limiting respiratory infections mainly in children.
Yanshan Gui, Bing Han, Jialong Wei, Danlei Sun, Laixian Zhou, Shuchen Yuan, Wenzhan Xie, Hui Feng   +7 more
doaj   +2 more sources

Circulation Patterns, Genetic Diversity, and Public Health Implications of Enterovirus D68, Europe, 2014–2024 [PDF]

Emerging Infectious Diseases
Enterovirus D68 (EV-D68) represents a continuing public health concern, given its association with severe respiratory illness and neurologic complications.
Cristina Andrés, Ignasi Prats-Méndez, Sofie Midgley, Natasa Berginc, Alejandra González-Sánchez, Caroline Klint Johannesen, Andrés Antón, Patricia Nadal-Barón, Thea K. Fischer, Heli Harvala, Kimberley S.M. Benschop   +10 more
doaj   +2 more sources

Enterovirus D68 pneumonia in two older patients: A case report and literature review [PDF]

Journal of International Medical Research
Enterovirus D68 mainly causes respiratory tract infections, with children being the main infected population and most adults experiencing latent infections. This report presents the cases of two older patients with enterovirus D68 pneumonia. Both of them
Weizhong Jin, Changcheng Shi, Yeping Li, Qingguo Wu   +3 more
doaj   +2 more sources

mRNA vaccine expressing enterovirus D68 virus-like particles induces potent neutralizing antibodies and protects against infection [PDF]

Molecular Therapy: Nucleic Acids
Enterovirus D68 (EV-D68) causes respiratory illness in children. It also causes severe paralysis called acute flaccid myelitis (AFM), which has become a global health threat. Here, we generated an mRNA vaccine expressing virus-like particles (VLPs) of EV-
Yuta Kunishima, Kota Senpuku, Chikako Kataoka-Nakamura, Toshiro Hirai, Yasuo Yoshioka   +4 more
doaj   +2 more sources

Outbreak of Enterovirus D68 in Young Children, Brescia, Italy, August to November 2024. [PDF]

J Med Virol
ABSTRACT Enterovirus D68 (EV‐D68) is responsible for a plethora of clinical manifestations ranging from asymptomatic infections to severe respiratory symptoms and neurological disorders. EV‐D68 was first detected in children with pneumonia in 1962 and, from then, only sporadic cases were reported until 2014, when outbreaks were notified across the ...
Messali S, Bertelli A, Dotta L, Giovanetti M, Sclavi L, Venneri G, Ciccozzi M, Badolato R, Caruso A, Caccuri F.   +9 more
europepmc   +2 more sources

Elucidating the role of human skeletal muscles in the pathogenesis of enterovirus D68 infection [PDF]

Life Science Alliance
Human skeletal muscles play a more direct role in the pathogenesis of enterovirus D68 through productive infection, which leads to structural destruction, functional loss, and hampered regeneration.
Brigitta M Laksono, Atze J Bergsma, Alessandro Iuliano, Dominique Y Veldhoen, Stefan van Nieuwkoop, Marjan Boter, Lonneke Leijten, Lisa Bauer, Bas B Oude Munnink, WWM Pim Pijnappel, Debby van Riel   +10 more
doaj   +2 more sources

Insights Into Enterovirus D68 Immunology: Unraveling the Mysteries of Host-Pathogen Interactions. [PDF]

Immun Inflamm Dis
This review provides a comprehensive overview of the immunological responses to Enterovirus D68, offering valuable insights for researchers, clinicians, and public health professionals working towards effective prevention and control strategies. ABSTRACT Background Enterovirus D68 (EV‐D68) has emerged as a significant respiratory and neurological ...
Naeem A, Naeem A, Bello MB, Bosaeed M.
europepmc   +2 more sources

Return of the Biennial Circulation of Enterovirus D68 in Colorado Children in 2024 Following the Large 2022 Outbreak [PDF]

Viruses
Enterovirus D68 (EV-D68) caused large biennial cyclical outbreaks of respiratory disease and cases of acute flaccid myelitis from 2014 to 2018 in the USA.
Hai Nguyen-Tran, Molly Butler, Dennis Simmons, Samuel R. Dominguez, Kevin Messacar   +4 more
doaj   +2 more sources

Enterovirus D68-associated respiratory and neurological illness in Spain, 2014–2018

Emerging Microbes and Infections, 2019
During 2014, enterovirus D68 (EV-D68) outbreaks were described globally, causing severe respiratory diseases in children and, in some cases, subsequent paralysis.
Jordi Reina, Antonio Moreno-Docón, Margarita Del Cuerpo   +2 more
exaly   +3 more sources