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Detection of Enterovirus D68 in Canadian Laboratories [PDF]
ABSTRACT The recent emergence of a severe respiratory disease caused by enterovirus D68 prompted investigation into whether Canadian hospital and provincial laboratories can detect this virus using commercial and laboratory-developed assays. This study demonstrated analytical sensitivity differences between commercial and laboratory-developed
Todd F, Hatchette +22 more
openaire +2 more sources
Enterovirus D68 and Human Respiratory Infections [PDF]
Enterovirus D68 (EV-D68) is a member of the species Enterovirus D in the genus Enterovirus of the Picornaviridae family. EV-D68 was first isolated in the United States in 1962 and is primarily an agent of respiratory disease. Infections with EV-D68 have been rarely reported until recently, when reports of EV-D68 associated with respiratory disease ...
Zichun, Xiang, Jianwei, Wang
openaire +2 more sources
In respond to acute flaccid paralysis (AFP) in association with Enterovirus D68 (EV-D68) infection, Taiwan Centers for Disease Control began to screen EV-D68 infection among each AFP patient since July 2015 and detected the first case in August 2016 ...
Hsin-Yi Wei +4 more
doaj +1 more source
Enterovirus D68 Subclade B3 in Children with Acute Flaccid Paralysis in West Africa, 2016
We tested for enterovirus D68 in fecal samples collected during June–September 2016 from 567 patients with acute flaccid paralysis in 7 West Africa nations. Children
Amary Fall +12 more
doaj +1 more source
Enterovirus D68: A clinically important respiratory enterovirus
Seasonal peaks of viral respiratory illnesses are common during late summer and early fall and have often been attributed to human rhinovirus. In the fall of 2014, the number of children hospitalized with severe lower respiratory symptoms and asthma suddenly increased, and the children tested positive by sequencing for enterovirus D68 (EV-D68).
Charles B, Foster +3 more
openaire +2 more sources
Enterovirus D68 Sequence Variations and Pathogenicity: A Review. [PDF]
Enterovirus D68 (EV-D68), a neurotropic respiratory pathogen, poses a considerable clinical threat through its link to pediatric acute flaccid myelitis (AFM) and severe respiratory illness. The possibility of recurrent epidemics, evidenced since the 2014 outbreak, remains a major concern.
Zhu Y, Wang L, Shen J.
europepmc +4 more sources
Background: Rhino-enteroviruses, particularly enterovirus strain D68 (EV-D68), have been associated with severe respiratory distress in children. The goal of this study was to compare the long-term outcomes of children with EV-D68 infection to that of ...
Charlotte Switzer +6 more
doaj +1 more source
MFSD6 is an entry receptor for enterovirus D68. [PDF]
With the near eradication of poliovirus due to global vaccination campaigns, attention has shifted to other enteroviruses that can cause polio-like paralysis syndrome (now termed acute flaccid myelitis)1-3. In particular, enterovirus D68 (EV-D68) is believed to be the main driver of epidemic outbreaks of acute flaccid myelitis in recent years4, yet not
Varanese L +18 more
europepmc +4 more sources
Zinc Influx Restricts Enterovirus D68 Replication [PDF]
Enterovirus D68 (EV-D68) is a respiratory viral pathogen that causes severe respiratory diseases and neurologic manifestations. Since the 2014 outbreak, EV-D68 has been reported to cause severe complications worldwide. However, there are currently no approved antiviral agents or vaccines for EV-D68.
Shunan Liu, Xia Cao, Haoran Guo, Wei Wei
openaire +3 more sources
Acute flaccid myelitis associated with enterovirus D68 in a non-epidemic setting
Acute flaccid myelitis (AFM) is a recently defined clinical disease accompanied by the national outbreak of enterovirus D68 (EV-D68) in the United States during the late summer/fall of 2014; 258 cases of EV-D68 and 59 cases of AFM were reported in Japan ...
Kazuki Hatayama +8 more
doaj +1 more source

