Results 1 to 10 of about 1,055,922 (317)

CYP51 Paralogue Structure Is Associated with Intrinsic Azole Resistance in Fungi

mBio, 2021
Azole antifungals are the main treatment for fungal disease in humans. Many species are intrinsically resistant to azoles—in other words all members of the species are resistant without prior exposure—and we do not understand why.
N. Van Rhijn, M. Bromley, M. Richardson, P. Bowyer   +3 more
doaj   +1 more source

Respiratory infections

European Respiratory Review, 2022
A new European Respiratory Review series explores respiratory infections https://bit.ly ...
Michael S. Niederman, Antoni Torres
openaire   +4 more sources

Japanese Encephalitis Vaccine Generates Cross-Reactive Memory T Cell Responses to Zika Virus in Humans

Journal of Tropical Medicine, 2022
Objective. Zika virus (ZIKV) and Japanese encephalitis virus (JEV) are mosquito-borne flaviviruses with sequence homology. ZIKV circulates in some regions where JEV also circulates, or where JE vaccination is used.
Ran Wang, Meng Zhang, Linlin Zhang, Mengjia Liu, Chao Shan, Jing An, Zhengde Xie   +6 more
doaj   +1 more source

Peripheral immune profile of children with Talaromyces marneffei infections: a retrospective analysis of 21 cases

BMC Infectious Diseases, 2021
Background Talaromyces marneffei (T. marneffei) is an opportunistic pathogen that infects immunodeficient children. The aim of the study is to determine the clinical features and peripheral immune state of Talaromyces marneffei (T.
Qiang Zeng, Yingkang Jin, Genquan Yin, Diyuan Yang, Wenyan Li, Tingting Shi, Gen Lu, Li Huang, Huifeng Fan   +8 more
doaj   +1 more source

Acute respiratory infections [PDF]

Current Problems in Pediatrics, 1974
In conclusion, the purpose of this dissertation has been to review the data on acute respiratory infections as to etiology, pathogenicity, clinical syndromes and treatment. It would take volumes to adequately discuss respiratory infections in all their complexity, and by the time any manuscript gets into print, it is likely to be outdated because of ...
D S, Seto, R M, Heller
openaire   +4 more sources

Composition and diversity analysis of the lung microbiome in patients with suspected ventilator-associated pneumonia

Critical Care, 2022
Background Ventilator-associated pneumonia (VAP) is associated with high morbidity and health care costs, yet diagnosis remains a challenge. Analysis of airway microbiota by amplicon sequencing provides a possible solution, as pneumonia is characterised ...
Dominic Fenn, Mahmoud I. Abdel-Aziz, Pouline M. P. van Oort, Paul Brinkman, Waqar M. Ahmed, Timothy Felton, Antonio Artigas, Pedro Póvoa, Ignacio Martin-Loeches, Marcus J. Schultz, Paul Dark, Stephen J. Fowler, Lieuwe D. J. Bos, The BreathDx Consortium   +13 more
doaj   +1 more source

Anti-protein immunoglobulin M responses to pneumococcus are not associated with aging

Pneumonia, 2018
Background The incidence of community-acquired pneumonia and lower respiratory tract infection rises considerably in later life. Immunoglobulin M (IgM) antibody levels to pneumococcal capsular polysaccharide are known to decrease with age; however ...
Esther L. German, Bahij Al-Hakim, Elena Mitsi, Shaun H. Pennington, Jenna F. Gritzfeld, Angie D. Hyder-Wright, Antonia Banyard, Stephen B. Gordon, Andrea M. Collins, Daniela M. Ferreira   +9 more
doaj   +1 more source

A genome-scale metabolic model of parasitic whipworm

Nature Communications, 2023
Genome-scale metabolic models are widely used to enhance our understanding of metabolic features of organisms, host-pathogen interactions and to identify therapeutics for diseases.
Ömer F. Bay, Kelly S. Hayes, Jean-Marc Schwartz, Richard K. Grencis, Ian S. Roberts   +4 more
doaj   +1 more source

The natural history of respiratory syncytial virus in a birth cohort : the influence of age and previous infection on reinfection and disease [PDF]

, 2012
This study aimed to quantify the effect of age, time since last infection, and infection history on the rate of respiratory syncytial virus infection and the effect of age and infection history on the risk of respiratory syncytial virus disease.
Bottomley, C, Medley, GF, Ochola, R., Nokes, D. James, Sande, CJ, Nokes, DJ, Ochola, R, Bottomley, C., Ohuma, EO, Okiro, E. A., Medley, Graham, Sande, C. J., Cane, Patricia, Okiro, EA, Ohuma, E. O., Cane, PA   +15 more
core   +1 more source

Single use and conventional bronchoscopes for Broncho alveolar lavage (BAL) in research: a comparative study (NCT 02515591)

BMC Pulmonary Medicine, 2017
Background Broncho alveolar lavage (BAL) is widely used for investigative research to study innate, cellular and humoral immune responses, and in early phase drug trials.
Seher Raza Zaidi, Andrea M. Collins, Elena Mitsi, Jesús Reiné, Kayleigh Davies, Angela D Wright, Jessica Owugha, Richard Fitzgerald, Amitava Ganguli, Stephen B Gordon, Daniela Mulari Ferreira, Jamie Rylance   +11 more
doaj   +1 more source