Results 41 to 50 of about 1,055,922 (317)

Plasmodium infection inhibits the expansion and activation of MDSCs and Tregs in the tumor microenvironment in a murine Lewis lung cancer model

Cell Communication and Signaling, 2019
Background A major challenge in the development of effective cancer immunotherapy is the ability of tumors and their microenvironment to suppress immune cells through immunosuppressive cells such as myeloid -derived suppressor cells and regulatory T ...
Dickson Adah, Yijun Yang, Quan Liu, Kranthi Gadidasu, Zhu Tao, Songlin Yu, Linglin Dai, Xiaofen Li, Siting Zhao, Limei Qin, Li Qin, Xiaoping Chen   +11 more
doaj   +1 more source

Lung microbiome on admission in critically ill patients with acute bacterial and viral pneumonia

Scientific Reports, 2023
Composition of pulmonary microbiome of patients with severe pneumonia is poorly known. The aim of this work was to analyse the lung microbiome of patients admitted to the intensive care unit  (ICU) with severe community acquired pneumonia (CAP) between ...
Jose María Marimón, Ane Sorarrain, Maria Ercibengoa, Nekane Azcue, Marta Alonso, Loreto Vidaur   +5 more
doaj   +1 more source

A double-blind randomised placebo-controlled trial investigating the effects of lesogaberan on the objective cough frequency and capsaicin-evoked coughs in patients with refractory chronic cough

ERJ Open Research, 2022
Objective Baclofen is a centrally acting γ-aminobutyric acid type B (GABAB) receptor agonist which reduces gastro-oesophageal reflux and suppresses the cough reflex; however, central nervous system side-effects limit its use.
Huda Badri, Carmen Gibbard, Dimitra Denton, Imran Satia, Bashar Al-Sheklly, Rachel J. Dockry, Kimberley Holt, Kevin McGuiness, Sam Treadway, Peter Whorwell, Lesley Houghton, Augustine Lee, K. Jane Escott, Theresa Lee, Greame Wilkinson, Alison Holt, Brendan J. Canning, Jacky A. Smith   +17 more
doaj   +1 more source

Respiratory infections and asthma [PDF]

Medical Journal of Australia, 2002
What we know: Respiratory viral infections caused by rhinoviruses, coronaviruses, influenza, parainfluenza and respiratory syncytial viruses (RSVs) are important triggers of asthma attacks. Mycoplasma and Chlamydia infections can also provoke asthma attacks, although less commonly. RSV infections probably do not cause asthma, but are potent triggers of
David, Isaacs, Preeti, Joshi
openaire   +2 more sources

Tools for detection of Mycoplasma amphoriforme : a primary respiratory pathogen?

, 2014
This work was supported by a Peter Samuel Royal Free Fund grant, the Primary Immunodeficiency Association, the Special Trustees of the Royal Free London NHS Foundation Trust, Hampstead, and the University of St.
Oravcova, Katarina, McHugh, Timothy D., Dilworth, Paul, Munro, Michelle, Templeton, Kate, Beattie, Thomas F., Ling, Clare L., Webster, David, McHugh, Timothy, Hardie, Alison, Pond, Marcus, Fulton, Naomi L., Gillespie, Stephen Henry, Workman, Sarita, Gillespie, Stephen H., Creer, Dean D., Beattie, Thomas Ferris   +16 more
core   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

The level and duration of RSV-specific maternal IgG in infants in Kilifi Kenya [PDF]

, 2009
Background Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infection in infants. The rate of decay of RSV-specific maternal antibodies (RSV-matAb), the factors affecting cord blood levels, and the relationship between ...
Nokes D. James, Ochola Rachel, Cane Patricia A., Scott, P. D. (Paul D.), Charles Sande, Medley Graham F., Fegan, Gregory, Scott, Paul D, Rachel Ochola, Greg Fegan, Cane, Patricia, Scott Paul D., Cane, Patricia A, Nokes, D. James, Paul D Scott, Sande Charles, Sande, Charles, Fegan Gregory, Medley, Graham F, Patricia A Cane, Fegan, Greg, D James Nokes, Ochola, Rachel, Medley, Graham, Graham F Medley, Nokes, D James, Gregory Fegan   +26 more
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

SARS-CoV-2-Induced Remission of Chemotherapy Resistance B-Cell Non-Hodgkin Lymphoma: A Case Report

Case Reports in Oncology
Introduction: Investigation on virus-host interaction may provide new clues for antitumor immunotherapy. Case Presentation: In this case report, we describe an unusual case of B-cell non-Hodgkin lymphoma in an aged woman who recovered following SARS-COV ...
Yan Xiao, Jinwei Wang, Kai Yang, Meiling Jiang, Bo Zhang   +4 more
doaj   +1 more source

Human adenovirus Coinfection aggravates the severity of Mycoplasma pneumoniae pneumonia in children

BMC Infectious Diseases, 2020
Background Mycoplasma pneumoniae (M. pneumoniae) is an important pathogen of community-acquired pneumonia (CAP) in children. The coinfection rate of M. pneumoniae pneumonia (MPP) can reach 52% in some areas, but the effects of coinfection with different ...
Jiaojiao Gao, Lili Xu, Baoping Xu, Zhengde Xie, Kunling Shen   +4 more
doaj   +1 more source