Results 21 to 30 of about 3,185,414 (312)

A genome-scale metabolic model of parasitic whipworm

Nature Communications, 2023
Genome-scale metabolic models are widely used to enhance our understanding of metabolic features of organisms, host-pathogen interactions and to identify therapeutics for diseases.
Ömer F. Bay, Kelly S. Hayes, Jean-Marc Schwartz, Richard K. Grencis, Ian S. Roberts   +4 more
doaj   +1 more source

Respiratory infections and asthma [PDF]

Respiratory Medicine, 2006
Respiratory tract infections caused by both viruses and/or atypical bacteria are involved in the pathogenesis of asthma. In particular, several viruses such as respiratory syncytial virus, rhinovirus and influenza/parainfluenza viruses may favour the expression of the asthmatic phenotype, being also implicated in the induction of disease exacerbations.
Pelaia G, VATRELLA, Alessandro, Gallelli L, Renda T, Cazzola M, Maselli R, Marsico S.A.   +6 more
openaire   +5 more sources

The incidence and clinical burden of respiratory syncytial virus disease identified through hospital outpatient presentations in Kenyan children [PDF]

, 2012
There is little information that describe the burden of respiratory syncytial virus (RSV) associated disease in the tropical African outpatient setting. Methods We studied a systematic sample of children aged
Bett, Ann, Okiro Emelda A., D James Nokes, Ann Bett, Bett Ann, Emelda A Okiro, Ngama Mwanajuma, Nokes D. James, Nokes, D. James, Mwanajuma Ngama, Ngama, Mwanajuma, Okiro, Emelda A.   +11 more
core   +1 more source

Protective effect of antibiotics against serious complications of common respiratory tract infections: retrospective cohort study with the UK General Practice research database [PDF]

, 2007
Objective: To determine the extent to which antibiotics reduce the risk of serious complications after common respiratory tract infections. Design: Retrospective cohort study.
Johnson, A. M., Livermore, D. M., Hayward, A.C., Livermore, D.M., Islam, A., Petersen, I., Duckworth, G., Johnson, A.M., Peterson, I., Hayward, A. C.   +9 more
core   +1 more source

Preparing for pandemics: a systematic review of pandemic influenza clinical management guidelines

BMC Medicine, 2022
Background The COVID-19 pandemic has highlighted the importance of evidence-based clinical decision-making. Clinical management guidelines (CMGs) may help reduce morbidity and mortality by improving the quality of clinical decisions.
Ishmeala Rigby, Melina Michelen, Vincent Cheng, Andrew Dagens, Dania Dahmash, Samuel Lipworth, Eli Harriss, Erhui Cai, Valeria Balan, Alexandra Oti, Reena Joseph, Helen Groves, Peter Hart, Shevin Jacob, Lucille Blumberg, Peter W. Horby, Louise Sigfrid   +16 more
doaj   +1 more source

CD25(+) Natural Regulatory T Cells Are Critical in Limiting Innate and Adaptive Immunity and Resolving Disease following Respiratory Syncytial Virus Infection [PDF]

, 2010
Regulatory CD4(+) T cells have been shown to be important in limiting immune responses, but their role in respiratory viral infections has received little attention.
Harker, JA, Johansson, C, Cecilia Johansson, Tregoning, John S, Jürgen Schwarze, Atabani, Sowsan F, Lee, Debbie C P, Atabani, SF, Lee, DC, Harker, James A E, Peter J. M. Openshaw, Schwarze, J, Harker, JAE, James A. E. Harker, Openshaw, Peter J M, Tregoning, JS, Lee, DCP, Johansson, Cecilia, John S. Tregoning, Openshaw, PJ, Schwarze, Jürgen, Openshaw, PJM, Debbie C. P. Lee, Sowsan F. Atabani   +23 more
core   +1 more source

Tools for detection of Mycoplasma amphoriforme : a primary respiratory pathogen? [PDF]

, 2014
This work was supported by a Peter Samuel Royal Free Fund grant, the Primary Immunodeficiency Association, the Special Trustees of the Royal Free London NHS Foundation Trust, Hampstead, and the University of St.
Oravcova, Katarina, McHugh, Timothy D., Dilworth, Paul, Munro, Michelle, Templeton, Kate, Beattie, Thomas F., Ling, Clare L., Webster, David, McHugh, Timothy, Hardie, Alison, Pond, Marcus, Fulton, Naomi L., Gillespie, Stephen Henry, Workman, Sarita, Gillespie, Stephen H., Creer, Dean D., Beattie, Thomas Ferris   +16 more
core   +1 more source

Severe lower respiratory tract infection in early infancy and pneumonia hospitalizations among children, Kenya. [PDF]

, 2013
Severe lower respiratory tract infection (LRTI) in infants caused by respiratory syncytial virus (RSV) has been associated with later pneumonia hospitalization among children.
Eric O. Ohuma, Nokes, D. James, Nokes, DJ, Ngama, Mwanajuma, Ngama, M, Patrick Kiio Munywoki, Bauni, E, Scott, J Anthony G, Ohuma, Eric O., Munywoki, Patrick Kiio, Scott, John, Ohuma, EO, J. Anthony G. Scott, Munywoki, PK, Bauni, Evasius, Mwanajuma Ngama, Scott, J. Anthony G., Nokes, D James, Ohuma, Eric O, Evasius Bauni, D. James Nokes   +20 more
core   +1 more source

Kinetics of the neutralizing antibody response to respiratory syncytial virus infections in a birth cohort [PDF]

, 2013
The kinetics of respiratory syncytial virus (RSV) neutralizing antibodies following birth, primary and secondary infections are poorly defined. The aims of the study were to measure and compare neutralizing antibody responses at different time points in ...
G.F. Medley, C.J. Sande, Sande, Charles J., P.A. Cane, Medley, Graham, Cane, Patricia, Nokes, D. James, Mutunga, M. N., M.N. Mutunga, E.A. Okiro, D.J. Nokes, Okiro, Emelda A.   +11 more
core   +1 more source

Risk factors for respiratory syncytial virus bronchiolitis hospital admission in New Zealand. [PDF]

, 2008
This study assessed risk factors for respiratory syncytial virus (RSV) hospitalization and disease severity in Wellington, New Zealand. During the southern hemisphere winter months of 2003--2005, 230 infants aged < 24 months hospitalized with ...
Rich, F. J., Pearce, N., Cheng, S., Cunningham, CW, Kirman, JR, Cunningham, C., Pierce, N., Cheng, S, Pearce, N, Grimwood, K., Cohet, C., Wood, C, Redshaw, N, Rich, F., Wood, C., Cunningham, C. W., Kirman, J., Grimwood, K, Rich, FJ, Cohet, C, Redshaw, N., Kirman, J. R.   +21 more
core   +1 more source