Results 31 to 40 of about 13,839 (200)

Acute flaccid myelitis in Switzerland - association with enterovirus D68. [PDF]

, 2023
Poliomyelitis-like acute flaccid myelitis associated with enterovirus D68 (EV-D68) has emerged globally during the past decade. Here we describe the first documented case reported from Switzerland, and a second, suspected case occurring in temporal ...
Ramette, Alban, Bieri, Andreas, Aebi, Christoph, Hoffmann, Angelika, Barbani, Maria Teresa, Bigi, Sandra   +5 more
core   +2 more sources

Mapping Attenuation Determinants in Enterovirus-D68 [PDF]

Viruses, 2020
Enterovirus (EV)-D68 has been associated with epidemics in the United Sates in 2014, 2016 and 2018. This study aims to identify potential viral virulence determinants. We found that neonatal type I interferon receptor knockout mice are susceptible to EV-D68 infection via intraperitoneal inoculation and were able to recapitulate the paralysis process ...
Ming Te Yeh, Sara Capponi, Adam Catching, Simone Bianco, Raul Andino   +4 more
openaire   +5 more sources

Circulation of Enterovirus D68 during Period of Increased Influenza-Like Illness, Maryland, USA, 2021

Emerging Infectious Diseases, 2022
We report enterovirus D68 circulation in Maryland, USA, during September–October 2021, which was associated with a spike in influenza-like illness. The characterized enterovirus D68 genomes clustered within the B3 subclade that circulated in 2018 in ...
Amary Fall, Nicholas Gallagher, C. Paul Morris, Julie M. Norton, Andrew Pekosz, Eili Klein, Heba H. Mostafa   +6 more
doaj   +1 more source

Enterovirus D68 VP3 Targets the Interferon Regulatory Factor 7 To Inhibit Type I Interferon Response

Microbiology Spectrum, 2023
Enterovirus D68 (EV-D68) is a globally emerging pathogen causing severe respiratory illnesses mainly in children. The protease from EV-D68 could impair type I interferon (IFN-I) production.
Jun Kang, Mengqian Huang, Jinyu Li, Keke Zhang, Cheng Zhu, Sihua Liu, Zhenwei Zhou, Tao Wang, Zhiyun Wang   +8 more
doaj   +1 more source

Re-emergence of enterovirus D68 in Europe after easing the COVID-19 lockdown, September 2021 [PDF]

, 2021
Acute flaccid myelitis; Enterovirus D68; SurveillanceMielitis flàcida aguda; Enterovirus D68; VigilànciaMielitis flácida aguda; Enterovirus D68; VigilanciaWe report a rapid increase in enterovirus D68 (EV-D68) infections, with 139 cases reported from ...
Aranzamendi Zaldumbide, Maitane, Vila Soler, Jorgina, Andrés Vergés, Cristina, Antón Pagarolas, Andrés, Benschop, Kimberley, Albert, Jan, Armannsdóttir, Brynja   +6 more
core   +1 more source

Enterovirus D68 molecular and cellular biology and pathogenesis [PDF]

Journal of Biological Chemistry, 2021
In recent years, enterovirus D68 (EV-D68) has advanced from a rarely detected respiratory virus to a widespread pathogen responsible for increasing rates of severe respiratory illness and acute flaccid myelitis (AFM) in children worldwide. In this review, we discuss the accumulating data on the molecular features of EV-D68 and place these into the ...
Matthew J. Elrick, Andrew Pekosz, Priya Duggal   +2 more
openaire   +2 more sources

The Emergence of Enterovirus-D68

Microbiology Spectrum, 2016
ABSTRACTEnterovirus-D68 (EV-D68) is a unique enterovirus, similar to human rhinoviruses, spread via the respiratory route and primarily causing respiratory disease. Increasing clusters of EV-D68 associated respiratory disease have been reported since 2008, with the largest reported outbreak occurring in North America in 2014.
Kevin, Messacar, Mark J, Abzug, Samuel R, Dominguez   +2 more
openaire   +2 more sources

Genomic analysis of enterovirus D68, including one strain isolated from a child with Wilson's disease in Taiwan

Journal of the Formosan Medical Association, 2019
North America experienced life-threatening outbreaks of enterovirus D68 (EV-D68) in 2014. We retrospectively detected EV-D68 from a child with Wilson's disease in 2008 in Taiwan. After comparing this EV-D68/Taiwan/2008 strain with EV-D68 genomes obtained
Yeh-Sheng Chien, Shu-Ting Luo, Kuo-Chien Tsao, Ying-Hsiang Wang, Tzou-Yien Lin, Yhu-Chering Huang, Min-Shi Lee   +6 more
doaj   +1 more source

Detection of Enterovirus D68 in Canadian Laboratories [PDF]

Journal of Clinical Microbiology, 2015
ABSTRACT The recent emergence of a severe respiratory disease caused by enterovirus D68 prompted investigation into whether Canadian hospital and provincial laboratories can detect this virus using commercial and laboratory-developed assays. This study demonstrated analytical sensitivity differences between commercial and laboratory-developed
Todd F, Hatchette, Steven J, Drews, Elsie, Grudeski, Tim, Booth, Christine, Martineau, Kerry, Dust, Richard, Garceau, Jonathan, Gubbay, Tim, Karnauchow, Mel, Krajden, Paul N, Levett, Tony, Mazzulli, Ryan R, McDonald, Alan, McNabb, Samira, Mubareka, Robert, Needle, Astrid, Petrich, Susan, Richardson, Candy, Rutherford, Marek, Smieja, Raymond, Tellier, Graham, Tipples, Jason J, LeBlanc   +22 more
openaire   +2 more sources

Enterovirus D68 and Human Respiratory Infections [PDF]

Seminars in Respiratory and Critical Care Medicine, 2016
Enterovirus D68 (EV-D68) is a member of the species Enterovirus D in the genus Enterovirus of the Picornaviridae family. EV-D68 was first isolated in the United States in 1962 and is primarily an agent of respiratory disease. Infections with EV-D68 have been rarely reported until recently, when reports of EV-D68 associated with respiratory disease ...
Zichun, Xiang, Jianwei, Wang
openaire   +2 more sources