Results 51 to 60 of about 2,978 (194)

Enteroviruses Remodel Autophagic Trafficking through Regulation of Host SNARE Proteins to Promote Virus Replication and Cell Exit

open access: yesCell Reports, 2018
Summary: Enterovirus D68 (EV-D68) is a medically important respiratory plus-strand RNA virus of children that has been linked to acute flaccid myelitis. We have determined that EV-D68 induces autophagic signaling and membrane formation.
Abigail K. Corona   +3 more
doaj   +1 more source

SIRT-1 is required for release of enveloped enteroviruses

open access: yeseLife, 2023
Enterovirus D68 (EV-D68) is a re-emerging enterovirus that causes acute respiratory illness in infants and has recently been linked to Acute Flaccid Myelitis.
Alagie Jassey   +7 more
doaj   +1 more source

Acute Flaccid Myelitis Associated with Enterovirus D68 in Children, Argentina, 2016

open access: yesEmerging Infectious Diseases, 2019
After a 2014 outbreak of severe respiratory illness caused by enterovirus D68 in the United States, sporadic cases of acute flaccid myelitis have been reported worldwide.
Carolina M. Carballo   +10 more
doaj   +1 more source

Molecular detection of enterovirus D68 among children with acute respiratory tract infection in Ghana

open access: yesAfrican Journal of Laboratory Medicine, 2019
Background: Acute respiratory tract infections of viral origin remain a leading cause of morbidity, mortality and economic loss regardless of age or gender. A small number of acute respiratory tract infection cases caused by enterovirus D68 (EV-D68) have
Joyce A. Kubi   +4 more
doaj   +1 more source

The pooled global case fatality rate of Enterovirus D68.

open access: yes, 2022
The pooled global case fatality rate of Enterovirus D68.
Hervé Raoul Tazokong (9306338)   +33 more
core   +1 more source

Evolution, geographic spreading, and demographic distribution of Enterovirus D68. [PDF]

open access: yes, 2022
Worldwide outbreaks of enterovirus D68 (EV-D68) in 2014 and 2016 have caused serious respiratory and neurological disease. We collected samples from several European countries during the 2018 outbreak and determined 53 near full-length genome ('whole ...
Cristina Andrés   +33 more
core   +1 more source

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

open access: yesAdvanced Science, EarlyView.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang   +13 more
wiley   +1 more source

Viral Detection and Clinical Disease Features in Pediatric Chronic Rhinosinusitis

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 3, June 2026.
ABSTRACT Objectives Chronic rhinosinusitis (CRS) results from complex host‐environment interactions with microbiome dysbiosis and viral infections postulated to drive inflammation and anatomic remodeling. This study investigates the impact of viral presence on pediatric sinonasal disease and clinical outcomes.
Mary C. Wilding   +7 more
wiley   +1 more source

The pooled global prevalence of Enterovirus D68 current infections.

open access: yes, 2022
The pooled global prevalence of Enterovirus D68 current infections.
Hervé Raoul Tazokong (9306338)   +33 more
core   +1 more source

Contemporary enterovirus-D68 isolates infect human spinal cord organoids

open access: yesmBio, 2023
Enterovirus D68 (EV-D68) is a nonpolio enterovirus associated with severe respiratory illness and acute flaccid myelitis (AFM), a polio-like illness causing paralysis in children.
Gabrielle Aguglia   +4 more
doaj   +1 more source

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