Results 61 to 70 of about 2,978 (194)

Enterovirus D68-Associated Respiratory Illness in Children.

JAMA Netw Open
ImportanceEnterovirus D68 (EV-D68) typically causes mild to severe acute respiratory illness (ARI). Testing and surveillance for EV-D68 in the US are limited, and important epidemiologic gaps remain.ObjectiveTo characterize the epidemiology and clinical severity of EV-D68 among US children seeking care for ARI from 2017 to 2022, using a multisite ...
Clopper BR, Lopez AS, Goldstein LA, Ng TFF, Toepfer AP, Staat MA, Schlaudecker EP, Sahni LC, Boom JA, Schuster JE, Selvarangan R, Halasa NB, Stewart LS, Williams JV, Michaels MG, Weinberg GA, Szilagyi PG, Klein EJ, Englund JA, McMorrow ML, Moline HL, Midgley CM.   +21 more
europepmc   +3 more sources

Lung Microbiome Diversity, Infection Dynamics, and Microbe‐Mediated Cross‐Protection

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
The protective role of the lung microbiome in maintaining respiratory health by promoting immune homeostasis, pathogen exclusion, and barrier integrity. Diverse microbial communities regulate immune maturation, enhance epithelial defenses, and contribute to antiviral responses, collectively preventing pathogen colonization and sustaining a balanced ...
Sana Arooj, Akmal Zubair, Syeda Zaira Batool, Granaz Niaz, Muhammad Ali, Yasir Waheed, Eman Ramadan Elsharkawy, Naila Afghan   +7 more
wiley   +1 more source

Organoids: From Bench to Bedside Applications

MedComm, Volume 7, Issue 6, June 2026.
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li, Rui Cao, Maochen Li, Zichao Tian, Huahao Fan, Bixia Hong, Xiaojuan Liu   +6 more
wiley   +1 more source

The pooled global prevalence of Enterovirus D68 past infections.

, 2022
The pooled global prevalence of Enterovirus D68 past infections.
Hervé Raoul Tazokong (9306338), Cyprien Kengne-Ndé (11824733), Richard Njouom (313047), Serge Alain Sadeuh-Mba (7513376), Raoul Kenfack-Momo (11985762), Jacqueline Félicité Yéngué (11824757), Ginette Irma Kame-Ngasse (11824736), Serges Tchatchouang (9306290), Jeannette Nina Magoudjou-Pekam (11824754), Efietngab Atembeh Noura (10688275), Jean Bosco Taya-Fokou (11824742), Chris Andre Mbongue Mikangue (9306320), Joseph Rodrigue Foe-Essomba (11824730), Cynthia Paola Demeni Emoh (9306308), Dimitri Tchami Ngongang (9306314), Lucy Ndip (844397), Arnol Bowo-Ngandji (9306305), Alex Durand Nka (8767053), Ndongo Dia (544177), Donatien Serge Mbaga (9306323), Sebastien Kenmoe (4557064), Alfloditte Flore Feudjio (11824739), Martin Gael Oyono (12060251), Marie Amougou Atsama (8431272), Dowbiss Meta-Djomsi (11985750), Larissa Gertrude Djukouo (11824760), Jean Thierry Ebogo-Belobo (9306293), Cromwel Zemnou-Tepap (12060245), Gadji Mahamat (9306299), Amary Fall (743678), Landry Kengne Gounmadje (12060248), Martin Maïdadi-Foudi (11985753), Inès Nyebe (11824751), Giuseppina La Rosa (288783)   +33 more
core   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, Volume 15, Issue 18, 15 May 2026.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Enterovirus D-68 Infection of Primary Rat Cortical Neurons: Entry, Replication, and Functional Consequences

mBio, 2023
Enterovirus D68 (EV-D68) is an emerging pathogen associated with mild to severe respiratory disease. Since 2014, EV-D68 is also linked to acute flaccid myelitis (AFM), causing paralysis and muscle weakness in children. However, it remains unclear whether
Katrien C. K. Poelaert, Regina G. D. M. van Kleef, Mengying Liu, Arno van Vliet, Heyrhyoung Lyoo, Lora-Sophie Gerber, Yoshiki Narimatsu, Christian Büll, Henrik Clausen, Erik de Vries, Remco H. S. Westerink, Frank J. M. van Kuppeveld   +11 more
doaj   +1 more source

Diversity of Rhinovirus and Enterovirus Infections Among Pediatric Patients Hospitalized in Wisconsin, 2022–2023

Journal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Severe rhinovirus (RV)/enterovirus (EV) respiratory infections in pediatric patients increased in the US during 2022–2023. This study aimed to characterize RV/EV genetic diversity among hospitalized children in Wisconsin and describe demographic and clinical factors of patients by RV/EV type.
Hannah L. Litwak, Carlos M. Perez, Allen Bateman, Kyley Anhalt, Xiaoyan Lu, Shannon Rogers, Brian Emery, Terry Fei Fan Ng, Caelin Cubenas, Cria O. Gregory, Clinton Paden, Thomas Haupt, Hannah L. Kirking, Hannah E. Segaloff   +13 more
wiley   +1 more source

Neutralizing Antibody against Enterovirus D68 in Children and Adults before 2014 Outbreak, Kansas City, Missouri, USA

Emerging Infectious Diseases, 2019
We evaluated enterovirus D68 seroprevalence in Kansas City, Missouri, USA, from samples obtained during 2012–2013. Neutralizing antibodies against Fermon and the dominant 2014 Missouri isolate were universally detected.
Christopher J. Harrison, William C. Weldon, Barbara A. Pahud, Mary Anne Jackson, M. Steven Oberste, Rangaraj Selvarangan   +5 more
doaj   +1 more source

Enterovirus D68 Antivirals: Past, Present, and Future

ACS Infectious Diseases, 2020
Enterovirus D68 (EV-D68) is an RNA virus that causes respiratory illnesses mainly in children. In severe cases, it can lead to neurological complications such as acute flaccid myelitis (AFM). EV-D68 belongs to the enterovirus genera of the Picornaviridae family, which also includes many other significant human pathogens such as poliovirus, enterovirus ...
Yanmei Hu, Rami Musharrafieh, Madeleine Zheng, Jun Wang   +3 more
openaire   +3 more sources

Enterovirus D68–Associated Acute Flaccid Myelitis in Immunocompromised Woman, Italy

Emerging Infectious Diseases, 2017
In Italy in 2016, acute flaccid myelitis developed in a woman who had received a hematopoietic stem cell transplant. Enterovirus D68 viral genome was detected in respiratory and cerebrospinal fluid samples, and the viral protein 1 sequence clustered with
Emanuela Giombini, Martina Rueca, Walter Barberi, Anna Paola Iori, Concetta Castilletti, Paola Scognamiglio, Francesco Vairo, Giuseppe Ippolito, Maria Rosaria Capobianchi, Maria Beatrice Valli   +9 more
doaj   +1 more source