Results 71 to 80 of about 2,978 (194)
Curcuminoids amplify host innate antiviral immunity via the CRYAB‐RBM26 axis in viral infection
DMC/CUR antagonize viral hijacking of host nucleic acid resources and finely regulate the induction and effector phases of the type I interferon (IFN‐I) pathway through the CRYAB‐RBM26 axis. This molecular axis serves as a key downstream regulator for DMC/CUR activation of the IFN‐I pathway.
Tingting Chen +18 more
wiley +1 more source
Low Circulation of Subclade A1 Enterovirus D68 Strains in Senegal during 2014 North America Outbreak
To retrospectively investigate enterovirus D68 circulation in Senegal during the 2014 US outbreak, we retrieved specimens from 708 persons, mostly children, who had acute respiratory symptoms during September–December 2014.
Amary Fall +8 more
doaj +1 more source
Bee products as alternatives in the treatment of viral infections
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba +3 more
wiley +1 more source
The State of Knowledge of the Primary and Secondary Metabolites of the Iris Genus
The genus Iris L. (Iridaceae) comprises over 320 species, primarily found in the northern hemisphere. Iris species are important in horticulture, folklore and medicine, and contain a variety of primary and secondary metabolites with significant biological activity.
Olha Mykhailenko +3 more
wiley +1 more source
Changes in transmission of Enterovirus D68 (EV-D68) in England inferred from seroprevalence data. [PDF]
The factors leading to the global emergence of Enterovirus D68 (EV-D68) in 2014 as a cause of acute flaccid myelitis (AFM) in children are unknown. To investigate potential changes in virus transmissibility or population susceptibility, we measured the ...
Nicholas C Grassly +13 more
core +1 more source
Distinct genetic clades of enterovirus D68 detected in 2010, 2013, and 2015 in Osaka City, Japan.
The first upsurge of enterovirus D68 (EV-D68), a causative agent of acute respiratory infections (ARIs), in Japan was reported in Osaka City in 2010. In this study, which began in 2010, we surveyed EV-D68 in children with ARIs and analyzed sequences of ...
Atsushi Kaida +12 more
doaj +1 more source
Enterovirus D68 Infection in Children with Acute Flaccid Myelitis, Colorado, USA, 2014
During August 8, 2014–October 14, 2014, a total of 11 children with acute flaccid myelitis and distinctive neuroimaging changes were identified near Denver, Colorado, USA.
Negar Aliabadi +9 more
doaj +1 more source
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro +5 more
wiley +1 more source
Acute flaccid myelitis (AFM) is a polio-like disease that results in paralysis in previously healthy persons. Although the definitive cause of AFM remains unconfirmed, enterovirus D68 (EV-D68) is suspected based on 2014 data demonstrating an increase in ...
Priyanka Uprety +10 more
doaj +1 more source
Enterovirus A‐71 Associated Parainfectious Movement Disorders in Children
Abstract Background Pediatric movement disorders can be challenging to characterize, given the phenotypic complexity and broad differential diagnosis. While genetic tests are often part of the diagnostic work‐up, it is important to consider acquired causes, which may require specific investigations.
Suus A. M. van Noort +6 more
wiley +1 more source

