Results 91 to 100 of about 32,839 (311)

Enterprise Modeling in Support of SOA Migration Analysis

, 2018
This paper shows how enterprise modeling can support a Service-Oriented Architecture (SOA) migration analysis in terms of (1) IT infrastructure understanding, (2) identifying and refining candidate services by means of analyzing both the current IT ...
Kaczmarek-Heß, Monika, de Kinderen, Sybren   +1 more
core   +1 more source

Modeling Trust in Enterprise Architecture: A Pattern Language for ArchiMate

, 2020
Part 2:Enterprise Modeling and Enterprise ArchitectureInternational audienceTrust is widely acknowledged as the cornerstone of relationships in social life. But what makes an agent trust a person, a resource or an organization?
Tony Clark, Glenda Amaral, Guizzardi, Giancarlo, Almeida, João, Balbir Barn, Tiago Prince Sales, Glenda C. M. Amaral, Daniele Porello, Vinay Kulkarni, Barat, Souvik, João Paulo A. Almeida, Sales, Tiago, Prince, Clark, Tony, PORELLO D, Kulkarni, Vinay, Giancarlo Guizzardi, Barn, Balbir, Souvik Barat, Porello, Daniele, Amaral, Glenda   +19 more
core   +1 more source

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

Advanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel, Sofia Kokkaliari, Qiwen Gao, Jinjing Chen, Larissa Costa de Almeida, Srinivasarao Tenneti, Derek A. Leas, Eli Levit, Lewis S. Alexander, Khalil A. Abboud, Pingrong Wei, Michael D. Cameron, James R. Rocca, Ranjala Ratnayake, Donna D. Zhang, Hendrik Luesch, Robert W. Huigens III   +16 more
wiley   +1 more source

Editorial Introduction to Issue 46 of CSIMQ: Advances in Modeling and Analysis of Socio‑Technical Systems

Complex Systems Informatics and Modeling Quarterly
Complex Systems Informatics and Modeling Quarterly (CSIMQ) continues to publish research that deepens our understanding of complex socio‑technical systems and advanced modeling practices.
Rébecca Deneckère, Martin Henkel
doaj   +1 more source

Methodology of problem space modeling in industrial enterprise management system [PDF]

Marketing i Menedžment Innovacij, 2015
The aim of the article. The aim of the article is to develop methodological principles for building a problem space model which can be integrated into industrial enterprise management system. The results of the analysis.
V.V. Glushchevsky
doaj  

Bringing Enterprise Modeling Closer to Model-Driven Development

, 2011
Enterprise Modeling (EM) provides the means for using models to represent organizational knowledge from different perspectives. When information systems (IS) are involved, Model-Driven Development (MDD) is an approach that focuses on the use of models as
Zikra, Iyad,, Stirna, Janis, Iyad Zikra, Jelena Zdravkovic, Stirna, Janis,, Janis Stirna, Zdravkovic, Jelena,, Zikra, Iyad, Zdravkovic, Jelena   +8 more
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Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

Advanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou, Yongfeng Chen, Longyou Xiao, Wei Qi, Tianshu Du, Qiang Sun, Borui Xue, Qinghe Zhao, Pengfei Xie, Zi Ye, Fei Han, Lingli Guo, Yang Jiao, Ranran Zhang, Hong Jia, Xiao Huang, Jianwei Guo, Peng Wang, Huayi Wang, Yuanrui Wang, Wenjing Chen, Haining Wu, Liumin He, Dawei Zhang   +23 more
wiley   +1 more source

From enterprise modelling to enterprise visual scenes

International Journal of Internet and Enterprise Management, 2005
This paper extends the definition and role of Enterprise Modelling (EM) and describes recent research results that have led to the definition of the next generation of enterprise modelling – Enterprise Visual Scenes (EVS). The focus is on the transition from EM to EVS and what the implications will be for industry, developers of solutions, system ...
Frank M. Lillehagen, John Krogstie, Helge Grenager Solheim   +2 more
openaire   +1 more source

The Research on Architecture of Enterprise modeling and modeling method

, 2001
The market is changing and can't be forecasted accurately in this information time. The enterprises often need reengineer their own business processes.
Zhu YL(朱云龙), Li WP(李伟平), Xue JS(薛劲松)   +2 more
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