Results 141 to 150 of about 1,553,241 (295)

Natural Negative Feedback Loops Confer Indica‐Japonica Differentiation for Grain Size Homeostasis in Rice

Advanced Science, EarlyView.
This study reveals the genetic and molecular mechanisms controlling grain size homeostasis through fine‐tuning OsGRX8 self‐expression by two natural negative feedback loops functioning in redox‐dependent or ‐independent manners and identifies two self‐regulatory haplotypes (SRHs) for the subspecies differentiation in rice.
Xingxing Li, Meng‐en Wu, Ziqi Qiao, Junkui Huang, Juncheng Zhang, Yang Ding, Junqing Zhu, Jingyue Xu, Yuxin Huang, Wei Li, Xiaomin Su, Yue Ding, Jianwei Zhang, Yibo Li   +13 more
wiley   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Transparent Transfer‐Free Ultrasmall Multilayer Graphene Microelectrodes Enable High Quality Recordings in Brain Slices

Advanced Science, EarlyView.
A transfer‐free fabrication method enables multilayer graphene microelectrodes as small as 10 µm, eliminating reliability issues of manual graphene transfer. These electrodes record neural activity in brain slices with exceptional signal‐to‐noise ratios (up to 25–40 dB) while maintaining optical transparency for multimodal applications.
Nerea de Alvarez de Eulate, Christos Pavlou, Gonzalo León González, María Camarena Pérez, Lukas Holzapfel, Zhenyu Gao, Sten Vollebregt, Vasiliki Giagka   +7 more
wiley   +1 more source

A Tangentially Sensitive Tactile Sensor Reveals the Stick‐Slip Mechanism and Enhances Robotic Tactile Sensing

Advanced Science, EarlyView.
An ultralight, multilayer anisotropic tactile sensor—an artificial Pacinian corpuscle—exhibits ultrahigh tangential sensitivity (1022 kPa−1) and spatiotemporal sensing. It discriminates static, sliding, and rolling contacts, detects incipient stick–slip via high‑frequency signatures, and enhances robotic touch (100%/98.18% accuracy for active/passive ...
Jinghui Wang, Xiaoyu Liu, Yujiao Du, Yepu Chen, Jieyi Guo, Linyuan Fan, Min Tang, Xiaofeng Qiao, Yuanjie Zhu, Zhiyang Zhang, Chaojie Dong, Lizhen Wang, Yubo Fan   +12 more
wiley   +1 more source

Rib‐Reinforced Ultralight and Ultra‐Strong Shell Lattices

Advanced Science, EarlyView.
This study thoroughly reveals the relation between the curvature and stress direction of triply periodic minimal surface (TPMS) thin shell lattices and proposes a novel rib reinforcement design strategy to incorporate ribs along the line of asymptotes (LOA) and the line of principal curvatures (LOC) to enhance the strength of ultralight TPMS shell ...
Winston Wai Shing Ma, Lei Zhang, Junhao Ding, Shuo Qu, Michael Yu Wang, Xu Song, Ming Wang Fu   +6 more
wiley   +1 more source

Spatial dynamics of lithium battery recycling enterprises in China: implications for smart waste management and public health. [PDF]

Front Public Health
Hu F, Yang H, Zhou X, Zhao S, Qiu L, Wei S, Hu J, Chen Y, Hu H, Zhou H.   +9 more
europepmc   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Ectonucleotidase expression on T-helper cells as a response assessment tool to immune-checkpoint therapy in head and neck cancers

Oral Oncology Reports
B. Arvind, Praneetha Puvvula, Shalini Thakur, Anand Subash, VishalUS. Rao   +4 more
doaj   +1 more source

Green agricultural product quality supervision based on prospect theory and evolutionary game theory for logistics enterprise live streaming. [PDF]

Sci Rep
Hu Q, Guo E, Feng F, Zhao S.
europepmc   +1 more source

Understanding the Roles of Microstructure and Viscoelasticity of Soft Ionic Elastomer for Super‐Capacitive Pressure Sensors

Advanced Science, EarlyView.
By engineering the PVA/H3PO4 ionic elastomer with optimized viscoelasticity and a height‐graded microstructure, the pressure sensor achieves a broad linear range up to 2000 kPa and a high sensitivity of 2.70 nF/kPa. These advancements underscore its strong potential for wearable electronics, including bio‐signal detection, health monitoring, and ...
Allen J. Cheng, Wenkai Chang, Zhuohan Cao, Zhao Sha, Shuai He, Ming Xuan Chua, Bingnong Jiang, Yuansen Qiao, Ziyan Gao, Wenkui Dong, Wengui Li, Liao Wu, Dewei Chu, Shuhua Peng   +13 more
wiley   +1 more source