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Advances and Challenges in Biomaterials for Tendon and Enthesis Repair
Bioactive MaterialsTendon and enthesis injuries are a global health problem affecting millions of people, causing huge medical expenditure and labor loss every year. However, due to their intricate tissue architecture, unique mechanical properties, and especially their sluggish and limited innate regenerative capacity, repairing these injuries remains a formidable ...
Haiying Zhou, Yangwu Chen
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Basic Concepts of Enthesis Biology and Immunology
The Journal of Rheumatology Supplement, 2009The article highlights key features of entheses relevant to understanding psoriatic arthritis (PsA). It is emphasized that entheses are regions of stress concentration and that stress levels are reduced by anatomical adaptations at the insertion site and its adjoining tissues.
Michael, Benjamin, Dennis, McGonagle
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Immunohistochemistry of the Enthesis Organ of the Human Achilles Tendon
Foot & Ankle International, 2004Background: The insertional region of the Achilles tendon includes: the fibrocartilage of the enthesis at the tendon-bone junction, the sesamoid fibrocartilage in the deep surface of the tendon, and the periosteal fibrocartilage covering the superior tuberosity of the calcaneus.
Luigi, de Palma +3 more
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SP0127 IL23: A Signal to the Enthesis?
Annals of the Rheumatic Diseases, 2013This lecture will explore the central importance of the powerful, pro-inflammatory cytokine interleukin(IL)-23 in spondyloarthropathy. Although the pathogenesis of these conditions has been highly enigmatic for decades, numerous lines of investigation have recently independently converged upon IL-23, demonstrating it to be fundamental to the biology of
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Usefulness of Ultrasonography in the Assessment of Peripheral Enthesis in Spondyloarthritis
Reumatología Clínica (English Edition), 2014Enthesitis is one of the characteristic etiopathogenic manifestations of spondyloarthritis. However, in clinical practice, its presence often goes unnoticed because of the lack of precision and sensitivity of physical examination to detect it. Viable, valid and reliable imaging tests are needed for early diagnosis, as well as a good sensitivity to ...
M Cristina, Mata Arnaiz +1 more
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The Enthesis Organ Concept and Its Relevance to the Spondyloarthropathies
2009A characteristic feature of the spondyloarthropathies is inflammation at tendon or ligament attachment sites. This has traditionally been viewed as a focal abnormality, even though the inflammatory reaction intrinsic to enthesitis may be quite extensive. We argue that the diffuse nature of the pathology is best understood in the context of an 'enthesis
Michael, Benjamin, Dennis, McGonagle
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Enthesis bilateral asymmetry in humans and African apes
HOMO, 2008Entheses (skeletal muscle and tendon attachment sites) have often been used to infer handedness and activity variability among human populations. However, the specific roles that intensity vs. frequency of muscle contractions play in modifying entheses are not well understood and the assumption that entheses reflect muscle activity levels has been ...
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