Results 31 to 40 of about 15,125 (212)

Enthesitis indices identify different patients with this characteristic in axial and peripheral spondyloarthritis and also in psoriatic arthritis: ASAS-PerSpA data

Arthritis Research & Therapy, 2023
Background In axial spondyloarthritis (axSpA), peripheral SpA (pSpA) and psoriatic arthritis (PsA), enthesitis is a hallmark clinical feature that can be assessed by the SPARCC index, LEI, MASES and MEI.
Raquel Ena María Granados, M. Lourdes Ladehesa-Pineda, M. Ángeles Puche-Larrubia, Alejandro Escudero-Contreras, Maxime Dougados, Eduardo Collantes-Estevez, Clementina López-Medina   +6 more
doaj   +1 more source

ASAS definition for sacroiliitis on MRI in SpA : applicable to children? [PDF]

, 2017
Background: The Assessment of Spondyloarthritis International Society (ASAS) definition for a'positive' Magnetic Resonance Imaging (MRI) for sacroiliitis is well studied and validated in adults, but studies about the value of this definition in children ...
Baraliakos, Xenofon, Dehoorne, Jo, Elewaut, Dirk, Herregods, Nele, Jans, Lennart, Jaremko, Jacob Lester, Joos, Rik, Van den Bosch, Filip, Van Vlaenderen, Joke, Varkas, Gaëlle, Verstraete, Koenraad   +10 more
core   +2 more sources

Secukinumab: a new treatment option for psoriatic arthritis [PDF]

, 2016
Introduction: Psoriatic arthritis (PsA) is an immune-mediated chronic inflammatory arthropathy associated with impaired physical function and reduced quality of life.
McInnes, Iain B., Mease, Philip
core   +1 more source

Secukinumab sustains improvement in signs and symptoms of psoriatic arthritis: 2 year results from the phase 3 FUTURE 2 study [PDF]

, 2017
Objectives. To assess long-term efficacy, safety and tolerability of secukinumab up to 104 weeks in patients with active PsA. Methods. Patients with PsA (n = 397) were randomized to s.c. secukinumab 300, 150 or 75 mg or placebo at baseline, weeks 1, 2,
Delicha, Eumorphia-Maria, Gottlieb, Alice B., Kajekar, Radhika, Kirkham, Bruce, McInnes, Iain B., Mease, Philip J., Mpofu, Shephard, Pricop, Luminita, Rahman, Proton, Ritchlin, Christopher T.   +9 more
core   +2 more sources

A model of chronic enthesitis and new bone formation characterized by multimodal imaging

Disease Models & Mechanisms, 2018
Enthesitis is a key feature of several different rheumatic diseases. Its pathophysiology is only partially known due to the lack of access to human tissue and the shortage of reliable animal models for enthesitis.
Christine Czegley, Clarissa Gillmann, Christine Schauer, Lisa Seyler, Christiane Reinwald, Madelaine Hahn, Michael Uder, Katja Jochmann, Elisabeth Naschberger, Michael Stock, Georg Schett, Tobias Bäuerle, Markus H. Hoffmann   +12 more
doaj   +1 more source

A clinical practice guideline for the screening and assessment of enthesitis in patients with spondyloarthritis

Frontiers in Immunology, 2022
ObjectiveThe aim of this review is to provide guidance on the selection of approaches to the screening and assessment of enthesitis in patients with spondyloarthritis (SpA).MethodsTwenty-four questions regarding the approaches to the screening and ...
Xinyu Wu, Dong Liu, Yanfei Li, Ya Xie, Liudan Tu, Yanli Zhang, Xi Zhang, Linkai Fang, Xiqing Luo, Zhiming Lin, Zetao Liao, Limin Rong, Jie Ren, Yuqi Zhou, Niansheng Yang, Jian Xu, Hua Zhang, Baijie Xu, Zhenbiao Wu, Feng Zhan, Zhenbin Li, Weiguo Xiao, Shengyun Liu, Yi Zhou, Shanhui Ye, Qing Lv, Lijun Zhang, Dongbao Zhao, Shanzhi He, Like Zhao, Lijun Wu, He Lin, Yunxiao Zhu, Donggeng Guo, Zehong Yang, Budian Liu, Kehu Yang, Jieruo Gu   +37 more
doaj   +1 more source

Progress in spondylarthritis immunopathogenesis of spondyloarthritis: which cells drive disease? [PDF]

, 2009
Spondyloarthritides, or SpA, form a cluster of chronic inflammatory diseases with the axial skeleton as the most typical disease localisation, although extra-articular manifestations such as intestinal inflammation may frequently occur during the course ...
Melis, Lode, Elewaut, Dirk
core   +2 more sources

The GRAPPA Sonographic Enthesitis Workshop [PDF]

The Journal of Rheumatology, 2019
Enthesitis is a key feature in psoriatic arthritis (PsA) and may be the initial site of musculoskeletal inflammation in patients with PsA. Ultrasound (US) could improve the accuracy of clinical enthesitis assessment, but at present no consensus exists on a global sonographic enthesitis scoring method that can evaluate the extent of enthesitis at the ...
Lihi, Eder, Gurjit S, Kaeley, Sibel Zehra, Aydin   +2 more
openaire   +2 more sources

Enthesopathies and enthesitis. Part 2: Imaging studies

Journal of Ultrasonography, 2015
The pathologies of tendon and ligament attachments are called enthesopathies. Enthesitis is one of enthesopathies and it is considered a characteristic sign of rheumatic diseases from the spondyloarthritis group, including peripheral spondyloarthritis.
Iwona Sudoł-Szopińska, Brygida Kwiatkowska, Monika Prochorec-Sobieszek, Grzegorz Pracoń, Marta Walentowska-Janowicz, Włodzimierz Maśliński   +5 more
doaj   +1 more source

Comparison of the Heel Enthesitis MRI Scoring System (HEMRIS) with clinical enthesitis and local metabolic activity on PET-CT

RMD Open, 2020
Objective To compare the Heel Enthesitis MRI Scoring model (HEMRIS) with clinical and PET/CT outcomes in patients with cutaneous psoriasis (Pso), psoriatic arthritis (PsA) or ankylosing spondylitis (AS).Methods This prospective, observational study ...
Pim A de Jong, Nienke J Kleinrensink, Wouter Foppen, Iris Ten Katen, Pieternella H van der Veen, Bo de Klerk, Suzanne C E Diepstraten, Emmerik F A Leijten   +7 more
doaj   +1 more source