Results 41 to 50 of about 15,125 (212)

Histopathology of the gut in rheumatic diseases [PDF]

open access: yes, 2018
The gastrointestinal tract regulates the trafficking of macromolecules between the environment and the host through an epithelial barrier mechanism and is an important part of the immune system controlling the equilibrium between tolerance and immunity ...
Ciccia F.   +4 more
core   +1 more source

Secukinumab efficacy on resolution of enthesitis in psoriatic arthritis: pooled analysis of two phase 3 studies

open access: yesArthritis Research & Therapy, 2019
Background Enthesitis is one of the psoriatic arthritis (PsA) domains. Patients with enthesitis are associated with worse outcomes than those without enthesitis.
Laura C. Coates   +11 more
doaj   +1 more source

Magnetic Resonance Imaging of Enthesitis in Spondyloarthritis, Including Psoriatic Arthritis—Status and Recent Advances

open access: yesFrontiers in Medicine, 2020
Enthesitis, inflammation at the attachment sites of tendons, ligaments, fascia, and joint capsules to bones plays a critical role in the pathogenesis of spondyloarthritis (SpA), including psoriatic arthritis (PsA).
Ashish J. Mathew   +5 more
doaj   +1 more source

Tumor necrosis factor inhibitors in psoriatic arthritis. [PDF]

open access: yes, 2017
INTRODUCTION: Psoriatic arthritis (PsA) is a chronic inflammatory disease that can result in significant disability. With the emergence of tumor necrosis factor inhibitors (TNFi), therapeutic outcomes in PsA have improved substantially.
Kraft, Walter K.   +2 more
core   +2 more sources

Ixekizumab and complete resolution of enthesitis and dactylitis: integrated analysis of two phase 3 randomized trials in psoriatic arthritis

open access: yesArthritis Research & Therapy, 2019
Background Ixekizumab improves signs/symptoms of psoriatic arthritis (PsA). We present an integrated analysis of baseline disease burden and post-baseline outcomes in ixekizumab-treated patients with enthesitis or dactylitis.
Dafna D. Gladman   +8 more
doaj   +1 more source

Efficacy and safety of secukinumab administration by autoinjector in patients with psoriatic arthritis: results from a randomized, placebo-controlled trial (FUTURE 3) [PDF]

open access: yes, 2018
Background: The study aimed to assess 52-week efficacy and safety of secukinumab self-administration by autoinjector in patients with active psoriatic arthritis (PsA) in the FUTURE 3 study (ClinicalTrials.gov NCT01989468).
Andersson, Mats   +11 more
core   +1 more source

Do diseases cause entheseal changes at fibrous entheses? [PDF]

open access: yesInternational Journal of Paleopathology, 2013
Fibrous entheses have been widely used to study activity-related stress to infer behavioural patterns in past populations. Unlike their fibrocartilaginous counterparts, the effect of disease processes has been less widely discussed in the osteoarchaeological literature.
openaire   +3 more sources

THE DIAGNOSTIC VALUE OF CLINICAL EXAMINATION AND ULTRASOUND STUDY OF ENTHESES FOR EARLY DETECTION OF PSORIATIC AND RHEUMATOID ARTHRITIS: REMARC STUDY

open access: yesНаучно-практическая ревматология, 2013
The diagnosis of enthesitis can help in differentiating early psoriatic arthritis (ePsA) from early rheumatoid arthritis (eRA).Objective. To estimate the diagnostic value of detecting enthesitis during clinical examination and ultrasound in ePsA and eRA ...
Tatiana Viktorovna Korotaeva   +8 more
doaj   +1 more source

Enthesitis-related arthritis: monitoring and specific tools

open access: yesJornal de Pediatria, 2022
Objectives: In this article, the authors aimed to review the different tools used in the monitoring of enthesitis-related arthritis. Sources: The authors performed a literature review on PubMed, Google Scholar, and Scopus databases.
Hanène Lassoued Ferjani   +6 more
doaj   +1 more source

Clinical Trials Supporting the Role of the IL-17/IL-23 Axis in Axial Spondyloarthritis

open access: yesFrontiers in Immunology, 2021
The term spondyloarthritis (SpA) encompasses a heterogeneous group of inflammatory musculoskeletal diseases with several common genetic background and clinical features, including the possible involvement of the axial skeleton with peripheral mono- or ...
Angela Ceribelli   +9 more
doaj   +1 more source

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