Results 41 to 50 of about 11,463 (219)

A model of chronic enthesitis and new bone formation characterized by multimodal imaging

Disease Models & Mechanisms, 2018
Enthesitis is a key feature of several different rheumatic diseases. Its pathophysiology is only partially known due to the lack of access to human tissue and the shortage of reliable animal models for enthesitis.
Christine Czegley, Clarissa Gillmann, Christine Schauer, Lisa Seyler, Christiane Reinwald, Madelaine Hahn, Michael Uder, Katja Jochmann, Elisabeth Naschberger, Michael Stock, Georg Schett, Tobias Bäuerle, Markus H. Hoffmann   +12 more
doaj   +1 more source

Enthesitis indices identify different patients with this characteristic in axial and peripheral spondyloarthritis and also in psoriatic arthritis: ASAS-PerSpA data

Arthritis Research & Therapy, 2023
Background In axial spondyloarthritis (axSpA), peripheral SpA (pSpA) and psoriatic arthritis (PsA), enthesitis is a hallmark clinical feature that can be assessed by the SPARCC index, LEI, MASES and MEI.
Raquel Ena María Granados, M. Lourdes Ladehesa-Pineda, M. Ángeles Puche-Larrubia, Alejandro Escudero-Contreras, Maxime Dougados, Eduardo Collantes-Estevez, Clementina López-Medina   +6 more
doaj   +1 more source

Clinical Enthesitis in Systemic Lupus Erythematosus (SLE) Patients and Its Relation to Disease Activity [PDF]

Minia Journal of Medical Research
Background: Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune illness with variable systemic manifestations. The association between illness activity and enthesitis remains incompletely understood. Entheseal involvement in SLE patients has
Faten Mohamed, Fatma Mohamed, Alaa Abdalla, Shimaa Ahmed   +3 more
doaj   +1 more source

Detection of Enthesitis in Children With Enthesitis‐Related Arthritis: Dolorimetry Compared to Ultrasonography [PDF]

Arthritis & Rheumatology, 2013
ObjectiveTo evaluate the distribution of enthesitis and the accuracy of physical examination with a dolorimeter for the detection of enthesitis in children, using ultrasound (US) assessment as the reference standard.MethodsWe performed a prospective cross‐sectional study of 30 patients with enthesitis‐related arthritis (ERA) and 30 control subjects ...
Pamela F, Weiss, Nancy A, Chauvin, Andrew J, Klink, Russell, Localio, Chris, Feudtner, Diego, Jaramillo, Robert A, Colbert, David D, Sherry, Ron, Keren   +8 more
openaire   +2 more sources

The GRAPPA Sonographic Enthesitis Workshop [PDF]

The Journal of Rheumatology, 2019
Enthesitis is a key feature in psoriatic arthritis (PsA) and may be the initial site of musculoskeletal inflammation in patients with PsA. Ultrasound (US) could improve the accuracy of clinical enthesitis assessment, but at present no consensus exists on a global sonographic enthesitis scoring method that can evaluate the extent of enthesitis at the ...
Lihi, Eder, Gurjit S, Kaeley, Sibel Zehra, Aydin   +2 more
openaire   +2 more sources

Magnetic Resonance Imaging of Enthesitis in Spondyloarthritis, Including Psoriatic Arthritis—Status and Recent Advances

Frontiers in Medicine, 2020
Enthesitis, inflammation at the attachment sites of tendons, ligaments, fascia, and joint capsules to bones plays a critical role in the pathogenesis of spondyloarthritis (SpA), including psoriatic arthritis (PsA).
Ashish J. Mathew, Ashish J. Mathew, Ashish J. Mathew, Ashish J. Mathew, Mikkel Østergaard, Mikkel Østergaard   +5 more
doaj   +1 more source

A clinical practice guideline for the screening and assessment of enthesitis in patients with spondyloarthritis

Frontiers in Immunology, 2022
ObjectiveThe aim of this review is to provide guidance on the selection of approaches to the screening and assessment of enthesitis in patients with spondyloarthritis (SpA).MethodsTwenty-four questions regarding the approaches to the screening and ...
Xinyu Wu, Dong Liu, Yanfei Li, Ya Xie, Liudan Tu, Yanli Zhang, Xi Zhang, Linkai Fang, Xiqing Luo, Zhiming Lin, Zetao Liao, Limin Rong, Jie Ren, Yuqi Zhou, Niansheng Yang, Jian Xu, Hua Zhang, Baijie Xu, Zhenbiao Wu, Feng Zhan, Zhenbin Li, Weiguo Xiao, Shengyun Liu, Yi Zhou, Shanhui Ye, Qing Lv, Lijun Zhang, Dongbao Zhao, Shanzhi He, Like Zhao, Lijun Wu, He Lin, Yunxiao Zhu, Donggeng Guo, Zehong Yang, Budian Liu, Kehu Yang, Jieruo Gu   +37 more
doaj   +1 more source

Clinical Trials Supporting the Role of the IL-17/IL-23 Axis in Axial Spondyloarthritis

Frontiers in Immunology, 2021
The term spondyloarthritis (SpA) encompasses a heterogeneous group of inflammatory musculoskeletal diseases with several common genetic background and clinical features, including the possible involvement of the axial skeleton with peripheral mono- or ...
Angela Ceribelli, Angela Ceribelli, Francesca Motta, Francesca Motta, Matteo Vecellio, Matteo Vecellio, Natasa Isailovic, Francesco Ciccia, Carlo Selmi, Carlo Selmi   +9 more
doaj   +1 more source

Ixekizumab and complete resolution of enthesitis and dactylitis: integrated analysis of two phase 3 randomized trials in psoriatic arthritis

Arthritis Research & Therapy, 2019
Background Ixekizumab improves signs/symptoms of psoriatic arthritis (PsA). We present an integrated analysis of baseline disease burden and post-baseline outcomes in ixekizumab-treated patients with enthesitis or dactylitis.
Dafna D. Gladman, Ana-Maria Orbai, Uta Klitz, James Cheng-Chung Wei, Gaia Gallo, Julie Birt, Suchitrita Rathmann, David Shrom, Helena Marzo-Ortega   +8 more
doaj   +1 more source

Ultrasound in the evaluation of enthesitis: status and perspectives [PDF]

, 2011
Introduction: An increasing number of studies have applied ultrasound to the evaluation of entheses in spondyloarthritis patients. However, no clear agreement exists on the definition of enthesitis, on the number and choice of entheses to examine and on ...
Joshua, F, Gandjbakhch, F, D'Agostino, M, Esperanza Naredo, OMERACT Ultrasound Task Force, Richard J Wakefield, Maria D'Agostino, Terslev, L, null null, Lene Terslev, Fredrick Joshua, Frédérique Gandjbakhch, Wakefield, RJ, Naredo, E, Iagnocco, Annamaria   +14 more
core   +3 more sources