Results 81 to 90 of about 15,466 (229)

Tofacitinib for the Treatment of Juvenile Idiopathic Arthritis: Patient‐Reported Outcomes in a Phase 3, Randomized, Double‐Blind, Placebo‐Controlled Withdrawal Trial

Arthritis &Rheumatology, EarlyView.
Objective Juvenile idiopathic arthritis (JIA) is associated with impaired overall health‐related quality of life (HRQoL). We evaluated the impact of tofacitinib on patient‐reported outcomes (PROs) in patients with JIA. Methods This was a post hoc analysis of a phase 3, randomized, double‐blind, placebo‐controlled withdrawal trial (NCT02592434) in ...
Hermine I. Brunner, Ekaterina Alexeeva, Marcia Bandeira, Ruy Carrasco, Jeffrey Chaitow, Peter Chiraseveenuprapund, Tracy V. Ting, Muferet Erguven, Beth Gottlieb, Sheila Knupp Oliveira, Pooja N. Patel, Seza Ozen, Claudia Saad Magalhaes, Inmaculada Calvo Penadés, David Gruben, Rebecca Germino, Holly B. Posner, Lori Stockert, Alberto Martini, Daniel J. Lovell, Nicolino Ruperto, for the Paediatric Rheumatology International Trials Organisation (PRINTO) and Pediatric Rheumatology Collaborative Study Group (PRCSG)   +21 more
wiley   +1 more source

Measuring the Impact: MRI Response of Sacroiliac Joints to TNF Inhibitors in Youth with Axial Disease

Arthritis &Rheumatology, Accepted Article.
Objective To evaluate the timeline for resolution of sacroiliac joint (SIJ) inflammation, changes in structural lesions, and their correlation with patient‐reported outcomes in youth with axial juvenile spondyloarthritis (axJSpA) initiating TNF inhibitor (TNFi).
Timothy G. Brandon, Rui Xiao, Daniel J. Lovell, Edward Oberle, Matthew L. Stoll, Nancy A. Chauvin, Michael L. Francavilla, Walter P. Maksymowych, Pamela F. Weiss   +8 more
wiley   +1 more source

Psoriatic arthritis: clinical and ultrasound parallels

Современная ревматология, 2020
Objective: to assess the relationship of the clinical characteristics and laboratory inflammatory markers to the ultrasound signs of synovitis and enthesitis in patients with psoriatic arthritis (PsA).Patients and methods.
I. F. Fairushina, E. R. Kirillova, D. I. Abdulganieva, E. V. Sukhorukova, E. I. Mukhametshina   +4 more
doaj   +1 more source

Psoriasis and associated variables in classification and outcome of juvenile idiopathic arthritis - an eight-year follow-up study [PDF]

, 2017
Background: To study the impact of psoriasis and features associated with psoriasis on classification and outcome in a population-based follow-up cohort of children with juvenile idiopathic arthritis (JIA).
Aalto, Kristiina, Berntson, Lillemor, Ekelund, Maria, Fasth, Anders, Herlin, Troels, Nielsen, Susan, Nordal, Ellen, Nordic Study Grp Pediat Rheumatol, Peltoniemi, Suvi, Rygg, Marite, Zak, Marek   +10 more
core   +2 more sources

Clinical Features and Therapeutic Outcomes in Pyoderma Gangrenosum: A Prospective Cohort Study

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis highly associated with systemic comorbidities. Accurate diagnosis and treatment remain challenging due to its rarity and clinical mimickers. Objectives To evaluate demographic, clinical features and treatment outcomes in patients referred with suspected PG at a tertiary ...
David Croitoru, Nesrine Brahimi, Haleh Zabihi, Cathryn Sibbald, Kyle Seigel, Delaram Shojaei, Eric McMullen, Afsaneh Alavi, Lily Archaempong, Aaron M. Drucker, Adam Weizman, Kenneth Croitoru, Robert Inman, Vincent Piguet   +13 more
wiley   +1 more source

Patients with Inflammatory Bowel Disease have Higher Sonographic Enthesitis Scores than Normal Individuals: Pilot Study in Taiwan

Journal of Medical Ultrasound, 2014
If a patient has inflammatory bowel disease (IBD) and enthesitis, he/she can be classified as having peripheral spondyloarthritis according to criteria set by the Assessment of Spondyloarthritis International Society.
Yu-Fen Hsiao, Shu-Chen Wei, Cheng-Hsun Lu, Cheng-Han Wu, Song-Chou Hsieh, Ko-Jen Li   +5 more
doaj   +1 more source

Tailored treatment options for patients with psoriatic arthritis and psoriasis: review of established and new biologic and small molecule therapies [PDF]

, 2016
The diverse clinical picture of PsA suggests the need to identify suitable therapies to address the different combinations of clinical manifestations. This review aimed to classify the available biologic agents and new small molecule inhibitors (licensed
Ciurtin, C, Elyoussfi, S, Thomas, BJ
core   +1 more source

Enthesitis in IBD Patients

Journal of Clinical Medicine
Inflammatory bowel disease (IBD) is marked by chronic inflammation of the gastrointestinal tract and encompasses two major subtypes, Crohn’s disease (CD) and ulcerative colitis (UC). IBD is frequently accompanied by extraintestinal manifestations (EIMs), with axial and peripheral spondyloarthritis (SpA) being the most common.
Ivna Akrapovic Olic, Jonatan Vukovic, Mislav Radic, Zeljko Sundov   +3 more
openaire   +2 more sources

Detection of Enthesitis in Children With Enthesitis‐Related Arthritis: Dolorimetry Compared to Ultrasonography [PDF]

Arthritis & Rheumatology, 2013
ObjectiveTo evaluate the distribution of enthesitis and the accuracy of physical examination with a dolorimeter for the detection of enthesitis in children, using ultrasound (US) assessment as the reference standard.MethodsWe performed a prospective cross‐sectional study of 30 patients with enthesitis‐related arthritis (ERA) and 30 control subjects ...
Pamela F, Weiss, Nancy A, Chauvin, Andrew J, Klink, Russell, Localio, Chris, Feudtner, Diego, Jaramillo, Robert A, Colbert, David D, Sherry, Ron, Keren   +8 more
openaire   +2 more sources

Approach to Nail Pitting in Pediatric and Adolescent Patients: A Dermatology Perspective

JEADV Clinical Practice, EarlyView.
ABSTRACT This narrative review aims to discuss the etiologies of nail pitting in pediatric and adolescent patients, while providing a framework for further evaluation of possible underlying systemic conditions and their clinical findings from a dermatologic standpoint.
Elizabeth Botto, Victoria Griffith, Samuel Stahly, Jere Mammino   +3 more
wiley   +1 more source