Results 181 to 190 of about 4,654,954 (329)

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

The <i>Drosophila</i> Connectome as a Computational Reservoir for Time-Series Prediction. [PDF]

Biomimetics (Basel)
Costi L, Hadjiivanov A, Dold D, Hale ZF, Izzo D.   +4 more
europepmc   +1 more source

An unorthodox entire function

Journal of Computational and Applied Mathematics, 2001
openaire   +2 more sources

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

A uniqueness theorem for entire functions [PDF]

, 1965
Richard F. DeMar
openalex   +1 more source

Albumin-bilirubin grade as an alternative to Child-Pugh class for evaluating liver function within staging systems for hepatocellular carcinoma. [PDF]

Discov Oncol
Guan MC, Ding Q, Zhao Q, Li N, Zhang RX, Zhang SY, Wang J, Zhu H.   +7 more
europepmc   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

On entire functions represented by Dirichlet series. IV [PDF]

, 1966
P. K. Kamthan
openalex   +1 more source

Rudolf Nieuwenhuys's later studies in neuroanatomy and functional neuroimaging. [PDF]

Brain Struct Funct
Turner R.
europepmc   +1 more source

Permutable entire functions [PDF]

Mathematische Zeitschrift, 1962
openaire   +1 more source