Results 121 to 130 of about 181,249 (295)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Entire functions of several variables: behaviour of directional derivatives

Carpathian Mathematical Publications
Let $h$ be a positive increasing on $[0;+\infty)$ function such that $h\Big(x+\frac{1}{h(x)}\Big)=O(h(x))$ as $x\to +\infty$. For measurable by Lebesgue set $E\subset[0;+\infty)$ of finite Lebesgue measure $\mathop{\rm meas}E=\int_{E}dx$, we define the asymptotic $h$-density of $E$ on $+\infty$ by \[{D}_{h}(E)= \varlimsup_{R \rightarrow +\infty} h(R ...
A.I. Bandura, S.I. Dubey, T.M. Salo, O.B. Skaskiv   +3 more
openaire   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Representation of logarithm of entire function in several complex variables

Karpatsʹkì Matematičnì Publìkacìï, 2012
The integral representation of some branch of an entire on $\mathbb{C}^n$ function which generalized the Poisson-Jensen-Stoll Formula is obtained.
Brodyak, O. Ya., Vasyl'kiv, Ya. V.
openaire   +3 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Knowledge and Awareness about Anesthesia and Perception about Anesthesiologists and their Role during the COVID-19 Pandemic among Patients at a Zonal Hospital: A Cross-sectional Survey

Journal of Marine Medical Society
Background: Anesthesia forms the cornerstone of the practice of modern medicine as we know it today. The field of anesthesia has evolved beautifully since its conception in the 1800s and today the reach of the anesthesiologist goes far beyond his role in
Mayank Rajput, Dewendra J. Gajbhiye, Nagesh Venkata Ivaturi, Shambhavi Rajiva, Vivek Yadav   +4 more
doaj   +1 more source

Approximation by polynomial projectors in several variables

, 2022
Dans le premier chapitre nous définissons un nouveau procédé pour amalgamer des projecteurs polynomiaux à moins de variables pour en obtenir un en plus de variables. Nous présentons ensuite de nombreuses propriétés algébriques de cette construction.
Bertrand, Francois
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Whittaker constants for entire functions of several complex variables [PDF]

Pacific Journal of Mathematics, 1971
openaire   +2 more sources