Results 101 to 110 of about 11,651,840 (352)
The role of fibroblast growth factors in cell and cancer metabolism
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
The Keller–Osserman-type conditions for the study of a semilinear elliptic system
We study the following system of equations: 0.1 {Δu1=p1(|x|)f1(u1,u2)in RN,Δu2=p2(|x|)f2(u1,u2)in RN. $$ \textstyle\begin{cases} \Delta u_{1}=p_{1} ( \vert x \vert ) f_{1} ( u_{1},u_{2} ) &\text{in }\mathbb{R}^{N}, \\ \Delta u_{2}=p_{2} ( \vert x \vert )
Dragos-Patru Covei
doaj +1 more source
Nondegeneracy of entire solutions of a singular Liouvillle equation [PDF]
We establish nondegeneracy of the explicit family of finite mass solutions of the Liouvillle equation with a singular source of integer multiplicity, in the sense that all bounded elements in the kernel of the linearization correspond to variations along the parameters of the family.
Pino Manresa, Manuel del +2 more
openaire +8 more sources
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Existence of entire solutions of some non-linear differential-difference equations
In this paper, we investigate the admissible entire solutions of finite order of the differential-difference equations ( f ′ ( z ) ) 2 + P 2 ( z ) f 2 ( z + c ) = Q ( z ) e α ( z ) $(f'(z))^{2}+P^{2}(z)f^{2}(z+c)=Q(z)e^{\alpha(z)}$ and ( f ′ ( z ) ) 2 + [
Minfeng Chen, Zongsheng Gao, Yunfei Du
doaj +1 more source
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Anisotropic entire large solutions
Given q∈(0,1], we construct nonradial entire large solutions to the equation Δu=uq in RN.
openaire +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman +3 more
wiley +1 more source

