Results 131 to 140 of about 8,788,651 (349)
On Almost Entire Solutions Of The Burgers Equation
Solutions that satisfy classically the Burgers equation except, perhaps, on a closed set S of the plane of potential singularities whose Hausdorff 1-measure is zero, $H^1(S) = 0$, are necessarily identically constant. We show this under the additional hypothesis that $S$ is a subset of a countable union of ordered graphs.
Alikakos, Nicholas, Gazoulis, Dimitrios
openaire +2 more sources
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää+2 more
wiley +1 more source
Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos+3 more
wiley +1 more source
Existence of positive entire solutions of semilinear ellipticequations on RN [PDF]
Norimichi Hirano
openalex +1 more source
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli+10 more
wiley +1 more source
Entire Solutions of the Abstract Cauchy Problem in a Hilbert Space [PDF]
Ralph deLaubenfels, Fuyuan Yao
openalex +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia+17 more
wiley +1 more source
On the blow-up and positive entire solutions of semilinear elliptic equations [PDF]
Jann–Long Chern
openalex +1 more source
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Construction of entire solutions for semilinear parabolic equations
Entire solutions of parabolic equations (those which are defined for all time) are typically rather rare. For example, the heat equation has exactly one entire solution - the trivial solution.
Michael Robinson
doaj