Results 131 to 140 of about 3,479,018 (289)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Entire solutions for a class of p-Laplace equations in R^2

open access: yesElectronic Journal of Differential Equations, 2010
We study the entire solutions of the p-Laplace equation $$ -hbox{div}(| abla u|^{p-2} abla u)+a(x,y)W'(u(x,y))=0, quad (x,y)in {mathbb{R}}^2 $$ where a(x,y) is a periodic in x and y, positive function.
Zheng Zhou
doaj  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Source inverse problem for fractional kinetic equation

open access: yesМатематичні Студії
We study the Cauchy problem for fractional kinetic equation in spaces with values in the entire scale of spaces of Bessel potentials, prove its unique, classical in time, solvability, obtaining an analogue of the maximum regularity of the solution ...
P. I. Boyko, H. P. Lopushanska
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Radial solutions of singular nonlinear biharmonic equations and applications to conformal geometry

open access: yesElectronic Journal of Differential Equations, 2003
Positive entire solutions of the singular biharmonic equation $Delta^2 u + u^{-q}=0$ in $mathbb{R}^n$ with $q>1$ and $ngeq 3$ are considered. We prove that there are infinitely many radial entire solutions with different growth rates close to quadratic ...
P. J. McKenna, Wolfgang Reichel
doaj  

On a long standing conjecture: positive Liouville Theorem for hypoelliptic Ornstein-Uhlenbeck operators

open access: yesBruno Pini Mathematical Analysis Seminar
Let $\mathcal{L}$ be the hypoelliptic Ornstein-Uhlenbeck operator associated with the pair of matrices (A,B). In 2004, Priola and Zabczyk proved the following Liouville-type theorem: every bounded entire solution of $\mathcal{L}u=0$ is constant if and ...
Alessia E. Kogoj   +2 more
doaj   +1 more source

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