Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Entire solutions for a class of variational problems involving the biharmonic operator and Rellich potentials [PDF]
, 2012 Mousomi Bhakta, Roberta Musina
openalex +1 more source
Existence of entire radial solutions to Hessian type system [PDF]
, 2022 Cui Ji-xian
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Entire Solutions of Nonhomogeneous Linear Differential Equations
Journal of Mathematical Analysis and Applications, 1999 A general theorem concerning the existence of entire solutions of a type of second-order nonhomogeneous linear differential equations is established provided that its coefficients and forcing function are themselves entire functions. The proof of this theorem involves obtaining solutions to a subsidiary equation involving a change of scale of the ...
openaire +2 more sources
A new proof for the existence of an equivariant entire solution connecting the minima of the potential for the system Δu - W_u (u) = 0 [PDF]
, 2011 Nicholas D. Alikakos
openalex +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
On the Allen-Cahn equation in the Grushin plane: a monotone entire solution that is not one-dimensional [PDF]
, 2008 Isabeau Birindelli, Enrico Valdinoci
openalex +1 more source
Chemotaxis systems with singular sensitivity and logistic source: Boundedness, persistence, absorbing set, and entire solutions [PDF]
, 2022 Halil İbrahim Kurt, Wenxian Shen
openalex +1 more source