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Computational Modeling of Entorhinal Cortex
Annals of the New York Academy of Sciences, 2000Computational modeling provides a means for linking the physiological and anatomical characteristics of entorhinal cortex at a cellular level to the functional role of this region in behavior. We have developed detailed simulations of entorhinal cortical neurons and networks, with an emphasis on the role of acetylcholine in entorhinal cortical function.
M E, Hasselmo +3 more
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The computational model of entorhinal cortex
2013 IEEE International Conference on Information and Automation (ICIA), 2013The entorhinal cortex (EC) plays a pivotal role for spatial representation and navigation in rat. Understanding how information is processed in the entorhinal cortex is essential to help us know the self-motion-based navigation. This article introduces the connection of entorhinal cortex and hippocampus, main cells in entorhinal cortex and their ...
Naigong Yu, Lin Wang, Huanzhao Chen
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Cytoarchitecture of the entorhinal cortex in schizophrenia
American Journal of Psychiatry, 1997The purpose of this study was to determine whether schizophrenia is associated with abnormalities in neuronal migration in the entorhinal cortex.Nissl-stained sections through three cytoarchitectonic subdivisions of the entorhinal cortex were examined in postmortem brain specimens from 10 schizophrenic subjects and 10 matched normal comparison subjects.
M, Akil, D A, Lewis
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Spatial Representation in the Entorhinal Cortex
Science, 2004As the interface between hippocampus and neocortex, the entorhinal cortex is likely to play a pivotal role in memory. To determine how information is represented in this area, we measured spatial modulation of neural activity in layers of medial entorhinal cortex projecting to the hippocampus.
Marianne, Fyhn +4 more
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2010
While decades of study have unraveled some of the basic principles of hippocampal structure and function, the adjacent entorhinal cortex (EC) has remained terra incognita in many respects. Recent studies suggest that the medial part of the entorhinal cortex is part of a two-dimensional metric map of the animal’s changing location in the environment.
Edvard I. Moser +2 more
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While decades of study have unraveled some of the basic principles of hippocampal structure and function, the adjacent entorhinal cortex (EC) has remained terra incognita in many respects. Recent studies suggest that the medial part of the entorhinal cortex is part of a two-dimensional metric map of the animal’s changing location in the environment.
Edvard I. Moser +2 more
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Hippocampus, 2011
AbstractThe lateral entorhinal cortex (LEC) provides a major cortical input to the hippocampal formation, equaling that of the medial entorhinal cortex (MEC). To understand the functional contributions made by LEC, basic knowledge of individual neurons, in the context of the intrinsic network, is needed.
Canto, C.B., Witter, M.P.
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AbstractThe lateral entorhinal cortex (LEC) provides a major cortical input to the hippocampal formation, equaling that of the medial entorhinal cortex (MEC). To understand the functional contributions made by LEC, basic knowledge of individual neurons, in the context of the intrinsic network, is needed.
Canto, C.B., Witter, M.P.
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Hippocampus, 2011
AbstractPrincipal neurons in different medial entorhinal cortex (MEC) layers show variations in spatial modulation that stabilize between 15 and 30 days postnatally. These in vivo variations are likely due to differences in intrinsic membrane properties and integrative capacities of neurons.
Canto, C.B., Witter, M.P.
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AbstractPrincipal neurons in different medial entorhinal cortex (MEC) layers show variations in spatial modulation that stabilize between 15 and 30 days postnatally. These in vivo variations are likely due to differences in intrinsic membrane properties and integrative capacities of neurons.
Canto, C.B., Witter, M.P.
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The Role of the Entorhinal Cortex in Paraphrenia
Current Psychiatry Reports, 2010Evidence derived from postmortem brain studies has implicated the uncal cortex in paraphrenia. In the present review, we expand on the anatomic and physiologic nuances endogenous to this region that make entorhinal cortex pathology an important clinicopathological correlate to paraphrenia.
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Entorhinal cortex modules of the human brain
The Journal of Comparative Neurology, 1996Much is known about modular organization in the cerebral cortex, but this knowledge is skewed markedly toward primary sensory areas, and in fact, it has been difficult to demonstrate elsewhere. In this report, we test the hypothesis that a unique form of modules exists in the entorhinal area of the human cortex (Brodmann's area 28).
A, Solodkin, G W, Van Hoesen
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Entorhinal cortex and consolidated memory
Neuroscience Research, 2014The entorhinal cortex is thought to support rapid encoding of new associations by serving as an interface between the hippocampus and neocortical regions. Although the entorhinal-hippocampal interaction is undoubtedly essential for initial memory acquisition, the entorhinal cortex contributes to memory retrieval even after the hippocampus is no longer ...
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