Results 51 to 60 of about 10,071,969 (331)

Mitochondria-DNA copy-number in osteoporosis and osteoarthritis among middle-aged women - A population-based cohort study

open access: yesOsteoarthritis and Cartilage Open
Background: Mitochondrial DNA copy number (mtDNA-CN) is associated with aging. A relationship between mtDNA-CN and degenerative disorders, e.g. osteoarthritis (OA) and osteoporosis (OP), has been suggested.
Christian Anker-Hansen   +5 more
doaj   +1 more source

Numerical Investigation on the Fluid Flow and Heat Transfer in the Entrance Region of Wavy Channel

open access: yes, 2013
In this study, the fluid flow and heat transfer in the entrance region in a converging-diverging channel with sinusoidal wall corrugations are investigated. Numerical solutions are obtained using the control-volume finite-difference method.
Nabou Mohamed   +4 more
semanticscholar   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

The role of Wakhan Road in commercial relations between Iran and China (From the 1st up to 8th Century A.H) [PDF]

open access: yesپژوهش‌های تاریخی ایران و اسلام, 2017
The main branch of the Silk Road, of which Constantinople and Chang-an were the two ends, had many secondary intersecting and parallel branches that have stayed in ignorance so far. At the threshold of entrance to Transoxania, in Amul, the Great route of
سید علی مزینانی،   +1 more
doaj   +1 more source

The Entrance Region of Circular Pipes Revisited

open access: yesOALib, 2016
The laminar flow in the entrance region of pipes having a circular cross section is investigated by the use of finite element solutions to the full Navier-Stokes equations in cylindrical coordinates. Because these solutions cover the complete three-dimensional geometry the usual development length is no longer a very interesting parameter as explained ...
openaire   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Duurzame communicatie met Wim Elving:S01 E05: Entrance onder de loep by Entrance - Centre of Expertise Energy

open access: yes
Podcastserie ENTRANCE ONDER DE LOEP (in het kort):Wim Elving is lector Sustainable Communications. Hij doet onderzoek naar communicatie-interventies die bijdragen aan de totstandkoming van een duurzame ...
Elving, Wim
core   +2 more sources

Theoretical Study of Mixed Convection In Isothermal Triangular Channel [PDF]

open access: yesEngineering and Technology Journal, 2005
Numerical study of mixed convection heat transfer within axial triangular channel was predicted. The channel surfaces have equal length and have a constant temperature. The fluid flow is hydrodynamic laminar buoyant and in thermal formed phase. The study
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

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