Results 171 to 180 of about 113,745 (253)

Quality by Design-Guided Transethosomal Gel of Donepezil Hydrochloride and Quercetin for Potential Alzheimer's Management: Stability-Indicating Eco-Compatible RP-HPLC Method. [PDF]

Drug Dev Res
Kumar A, Kaushik A, Devi A, Ankalgi AD, Ashawat MS, Alharbi HM, Amin M, Khojah AA, Ahmad S, Zaki MEA.   +9 more
europepmc   +1 more source

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source

Pyogenic Granuloma in the Sinonasal Cavity: A Potential 38-Year Latency Following Foreign Body Entrapment. [PDF]

Int Med Case Rep J
Ghazizadeh M, Hooshmandnia S, Hemmat Esfeh M, Elyasi M.   +3 more
europepmc   +1 more source

A mouse model of mechanical stress injury to the basal ganglia using thermosensitive PNIPAM hydrogel for intracerebral hemorrhage research

Animal Models and Experimental Medicine, EarlyView.
In this study, we established a novel mouse model of intracerebral hemorrhage (ICH) by stereotactically injecting thermosensitive PNIPAM hydrogel into the internal capsule to impose localized mechanical stress on the corticospinal tract, which provides a straightforward and reproducible tool for preclinical studies on focal mechanical stress–induced ...
Mingxi Li, Yujie Chen, Rongsu Huang, Min Xia, Chao Mi, Yuan Tian, Peiwen Guo, Taotao Jin, Shilei Hao, Hua Feng, Yujie Chen, Zhi Chen   +11 more
wiley   +1 more source

Successful Endovascular Retrieval of a Partially Disrupted Catheter Using a Crossing Catheter: A Bailout Technique for Severely Calcified Peripheral Lesions. [PDF]

Ann Vasc Dis
Oshima K, Ichihashi S, Chanoki Y, Iwakoshi S, Nakai T, Shimizu S, Okuyama T, Tanaka T.   +7 more
europepmc   +1 more source

Baseline podocyte‐associated state and persistent cell–matrix transcriptional programs are associated with BALB/c substrain differences in adriamycin nephropathy

Animal Models and Experimental Medicine, EarlyView.
Two closely related BALB/c substrains exhibit different early responses to adriamycin (ADR)‐induced nephropathy. BALB/cByJcl mice showed lower baseline WT1‐positive nuclei counts and NPHS1 immunoreactivity than BALB/cAJcl mice, together with extracellular matrix and integrin programs that were enriched at baseline and persisted at Day 5.
Ryuya Nakagawa, Masaki Watanabe, Koyuki Kawamoto, Momoka Hiratsuka, Takeru Sasaki, Nobuya Sasaki   +5 more
wiley   +1 more source

Four‐Dimensional Electrochemiluminescence Microscopy Enables Depth‐Resolved Imaging of Single, Living Spheroids

Angewandte Chemie, EarlyView.
A hybrid “confocal” electrochemiluminescence (ECL) microscopy combines depth‐resolved and time‐resolved imaging to visualize ECL processes across three spatial dimensions and time. By exploiting sluggish coreactant kinetics at ITO electrodes, homogeneous redox propagation enables depth‐resolved, single‐cell resolution mapping of living multicellular ...
Elisa D'Arrigo, Vanshika Gupta, Bertrand Goudeau, Jeffrey E. Dick, Neso Sojic   +4 more
wiley   +2 more sources

Nontraumatic unilateral ureteral entrapment at the sacroiliac joint: A rare cause of obstructive uropathy. [PDF]

Radiol Case Rep
Dave R, Panchal K, Patel N, Shah D.
europepmc   +1 more source

Neuroprotection after transient middle cerebral artery occlusion in male rats using kojic acid nanostructured lipid carriers: A behavioral, biochemical, and histological study on hippocampal CA1 region

Animal Models and Experimental Medicine, EarlyView.
This study demonstrates that kojic acid–loaded nanostructured lipid carriers (KA‐NLC) provide significant neuroprotection in a male rat model of middle cerebral artery occlusion (MCAO)–induced stroke. Treatment with KA‐NLCs reduced cerebral edema, improved motor and coordination balance and neurological scores, and enhanced spatial and avoidance memory.
Mobina Gheibi, Erfan Ghadirzadeh, Javid Tebyani, Seyedeh Mohadeseh Moyaedi, Khadijeh Khezri, Majid Saeedi, Ali Siahposht‐Khachaki, Narges Karimi, Melika Pourhossein, Shiva Shadi, Sasan Shafiei, Atena Sharifi‐Razavi   +11 more
wiley   +1 more source

Photoactivated Platinum Complexes: Targeting Membrane Proteins and Organelles for Precision Cancer Therapy

Angewandte Chemie, EarlyView.
This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen, Qiyuan Zhou, Jiaqian Xu, Guangyu Zhu   +3 more
wiley   +2 more sources