Results 81 to 90 of about 382,531 (295)

Improvement of activity of entrepreneurs and enterprise structures

open access: yesПутеводитель предпринимателя, 2020
Problems and questions of development and improvement of entrepreneurship and enterprise structures in the country are considered in the article. It is defined that the main target results of their activity are need of carrying out and successful ...
L. A. Akhmetov   +2 more
doaj  

Preservation of rare plants of Boysun-Cholbair mountains [PDF]

open access: yesE3S Web of Conferences
The article aims to study the causes of "desertification", which is one of the main issues of today, and its negative consequences. The most current method for studying and assessing desertification is large-scale mapping of ecosystem components using ...
Sodikova Dilfuza   +3 more
doaj   +1 more source

Intrapreneurship or entrepreneurship? [PDF]

open access: yesJournal of Business Venturing, 2009
Abstract I explore the factors that determine whether new business opportunities are exploited by starting a new venture for an employer (‘nascent intrapreneurship’) or independently (‘nascent entrepreneurship’). Analysis of a nationally representative sample of American adults gathered in 2005–06 uncovers systematic differences between the drivers ...
openaire   +3 more sources

Grain‐Boundary‐Enriched Cocatalyst Coupled With CuSCN Hole Transport Layer for Efficient Solar Water Oxidation in BiVO4 Photoanode

open access: yesAdvanced Science, EarlyView.
A grain‐boundary‐enriched NiFe cocatalyst is coupled with a CuSCN hole transport layer on BiVO4 photoanodes. The integrated architecture promotes hole extraction, interfacial charge transfer, and surface OER kinetics, highlighting cocatalyst microstructure regulation as a complementary strategy to hole transport layer engineering. ABSTRACT Solar‐driven
Wei Zhao   +8 more
wiley   +1 more source

USP4‐Dependent CHAF1B Stabilization Regulates Distinct SETDB1 Ubiquitin States Linked to AKT T308 Signaling and Lipogenic Remodeling in HCC

open access: yesAdvanced Science, EarlyView.
USP4 stabilizes CHAF1B by limiting K48‐linked ubiquitination. Stabilized CHAF1B supports UHRF1‐associated K63‐linked SETDB1 ubiquitination and cytoplasmic redistribution, whereas CHAF1B loss favors VHL‐dependent K11‐associated degradative ubiquitination and proteasomal loss of SETDB1.
Saiyan Bian   +9 more
wiley   +1 more source

Metabolic Signatures for Liver Cancer Diagnosis and Mechanistic Insights: A Large‐Scale, Multicenter Study

open access: yesAdvanced Science, EarlyView.
A large‐scale multicenter serum metabolomics study (13 centers, n = 2,149) identified a 9‐metabolite + AFP diagnostic signature for liver cancer (AUC = 0.93). Among the signature, nicotinamide (NAM) was validated as an oncometabolite: NAM enhances NAD+ synthesis, activating SIRT1 to deacetylate and stabilize HIF1α, thereby driving glycolysis, MAPK ...
Yongjie Xu   +13 more
wiley   +1 more source

The Social Imaginary of Emancipation in Entrepreneurship

open access: yes, 2022
doi: 10.1177/1042258720959251This article contributes to the research agenda of emancipatory entrepreneurship by developing the understanding of emancipation as a social imaginary in entrepreneurship.
Kibler, Ewald, Laine, Lauri
core   +1 more source

Hepatic Lipid Stress Drives Metabolic Dysfunction‐Associated Steatohepatitis Progression through FTO O‐GlcNAcylation‐Induced m6A Demethylation of HRAS

open access: yesAdvanced Science, EarlyView.
Lipid stress drives O‐GlcNAcylation of the m6A demethylase FTO at Ser195, enhancing its stability and demethylase activity. This modification removes m6A from HRAS mRNA, preventing its degradation and activating PI3K/AKT signaling to promote hepatic steatosis and inflammation.
Jia‐Xin Yin   +9 more
wiley   +1 more source

Entrepreneurship education in entrepreneurship laboratories

open access: yesThe International Journal of Management Education, 2023
nadia di paola   +2 more
openaire   +2 more sources

Aged ZnO Nanoparticles Promote Breast Cancer Lung Metastasis by Remodeling the Pulmonary Microenvironment Through the CXCL10/Wnt/β‐Catenin Axis

open access: yesAdvanced Science, EarlyView.
In summary, pulmonary exposure to ZnO NPs, particularly aged NPs, promotes breast cancer metastasis by remodelling the lung tumour microenvironment. Aged ZnO NPs enrich M2‐macrophages, MDSCs and activated CAFs to form an immunosuppressive metastatic niche. CXCL10 from these cells drives metastasis via Wnt/β‐catenin activation.
Yong Zhu   +8 more
wiley   +1 more source

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