Results 91 to 100 of about 1,285,086 (339)

Mean Entropies

open access: yesOpen Systems & Information Dynamics, 2005
Entropies are expressed in terms of mean values, and not as weighted arithmetic means of their generating functions, which result in pseudo-additive entropies. The Shannon entropy corresponds to the logarithm of the inverse of the geometric mean, while the Rényi entropy, more generally, to the logarithm of the inverse of power means of order τ < 1 ...
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

A generalized approach for enhancing contact-electro-catalysis of oxides in a broad temperature range by fluorination

open access: yesNature Communications
Contact-electro-catalysis (CEC) has emerged as a sustainable and effective strategy for promoting chemical reactions. While polymers are the mostly used CEC catalysts, their limited contact-electrification (CE) performance at high temperatures limits the
Ziming Wang   +8 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Three Key Aspects of Electron Transfer Behavior in Single-Electrode Triboelectric Nanogenerators for Sensing Optimization

open access: yesSensors
With the rapid development of the Internet of Things, self-powered sensing technology has become a crucial solution for scenarios where an external power supply is inconvenient or unavailable, such as wild monitoring and flexible wearables.
Dazheng Shi   +4 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Electron Redistribution Drives Structural Ordering in Sulfate (SO4) Adlayers

open access: yesChemElectroChem
In this work, the coadsorption of SO4 and H2O at the Au(111)‐electrolyte interface is investigated. It is uncovered how electron redistribution between coadsorbates correlates with the formation of tightly packed (√3a) SO4‐adsorbate chains, which have ...
Marcus F. Nygaard   +4 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

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