Results 81 to 90 of about 449,947 (310)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

A generalized approach for enhancing contact-electro-catalysis of oxides in a broad temperature range by fluorination

open access: yesNature Communications
Contact-electro-catalysis (CEC) has emerged as a sustainable and effective strategy for promoting chemical reactions. While polymers are the mostly used CEC catalysts, their limited contact-electrification (CE) performance at high temperatures limits the
Ziming Wang   +8 more
doaj   +1 more source

A Comment on the Relation between Diffraction and Entropy

open access: yes, 2012
Baake M, Grimm U. A Comment on the Relation between Diffraction and Entropy. Entropy. 2012;14(12):856-864.Diffraction methods are used to detect atomic order in solids.
Uwe Grimm   +3 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Free entropy

open access: yesBulletin of the London Mathematical Society, 2000
Free entropy is the analogue of entropy in free probability theory. The paper is a survey of free entropy, its applications to von Neumann algebras and its connections to random matrix theory, as well as a discussion of open problems and of a basic variational problem, connected to random multimatrix models.
openaire   +3 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Electron Redistribution Drives Structural Ordering in Sulfate (SO4) Adlayers

open access: yesChemElectroChem
In this work, the coadsorption of SO4 and H2O at the Au(111)‐electrolyte interface is investigated. It is uncovered how electron redistribution between coadsorbates correlates with the formation of tightly packed (√3a) SO4‐adsorbate chains, which have ...
Marcus F. Nygaard   +4 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

The minimal entropy problem for 3-manifolds with zero simplicial volume [PDF]

open access: yes, 2003
In this note, we consider the minimal entropy problem, namely the question of whether there exists a smooth metric of minimal (topological) entropy, for certain classes of closed 3 ...
Anderson, J.W.   +3 more
core  

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