Results 81 to 90 of about 1,137,287 (295)
Entropy production in systems with long range interactions
On a fine grained scale the Gibbs entropy of an isolated system remains constant throughout its dynamical evolution. This is a consequence of Liouville's theorem for Hamiltonian systems and appears to contradict the second law of thermodynamics.
Levin, Yan, Pakter, Renato
core +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Topological Entanglement Entropy [PDF]
4 pages, 3 eps figures.
Kitaev, Alexei, Preskill, John
openaire +4 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Entropy, neutro-entropy and anti-entropy for neutrosophic information
This approach presents a multi-valued representation of the neutrosophic information. It highlights the link between the bifuzzy information and neutrosophic one. The constructed deca-valued structure shows the neutrosophic information complexity.
openaire +2 more sources
Entropies are expressed in terms of mean values, and not as weighted arithmetic means of their generating functions, which result in pseudo-additive entropies. The Shannon entropy corresponds to the logarithm of the inverse of the geometric mean, while the Rényi entropy, more generally, to the logarithm of the inverse of power means of order τ < 1 ...
openaire +2 more sources
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Contact-electro-catalysis at Dynamic Semiconductor–Water Junctions
Junctions are the fundamental elements of semiconductor devices, which are crucial for advancements in modern technology. However, most junctions involve static solid interfaces. Here, we studied a dynamic Schottky-like junction formed at a semiconductor–
Zhanqi Liu +7 more
doaj +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source

